CLARITY News and Research

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The lipid-exchanged, anatomically rigid, imaging/immunostaining compatible, tissue hydrogel (CLARITY) method was initially designed in 2013 by Chung and Deisseroth at the Stanford University School of Medicine. Using this process, post-mortem organs can be labeled for proteins and nucleic acids, enabling analysis of intact samples to create detailed 3D images.

How women in England faced childbirth in the COVID-19 pandemic

Pregnant women have suffered considerable uncertainty during the COVID-19 pandemic. Not only were the effects of the virus on the baby unknown, but social restrictions in place threatened their ability to plan their delivery experience or have their birthing partners with them. This is the focus of a new paper, which illustrates the need to provide proper guidance and support to pregnant women during such periods, especially allowing them to feel supported and in control of their childbirth experience.

8 Jul 2021

B cell depleting agents can cause altered immune responses to COVID-19 vaccines, suggests study

A new preprint, available on the medRxiv* server, describes altered responses to the use of the highly effective messenger RNA (mRNA) vaccines from Pfizer/BioNTech and Moderna in patients with multiple sclerosis on anti-CD20 (MS-aCD20) monotherapy.

2 Jul 2021

New neuronal circuit may help control which sensory information is relayed to the auditory cortex

A team of neuroscientists at the Beckman Institute for Advanced Science and Technology led by Baher Ibrahim and Dr. Daniel Llano published a study in eLife that furthers our understanding of how the brain perceives everyday sensory inputs.

30 Jun 2021

A study on hospitalized COVID-19 patients who received plasma therapy

A new study has been published which focuses on the evaluation of the outcomes of infected COVID-19 patients who were treated with CCP therapy.

23 Jun 2021

Experts call on the government to suspend daily contact testing trials in schools

Daily contact testing trials in schools are unethical, and extending them to include the delta variant puts everyone at risk, warn experts in The BMJ today.

21 Jun 2021

Study: Patients with two SARS-CoV-2 variants are less likely to be asymptomatic compared to control group

Although two SARS-CoV-2 variants are associated with higher transmission, patients with these variants show no evidence of higher viral loads in their upper respiratory tracts compared to the control group, a Johns Hopkins School of Medicine study found.

21 Jun 2021

Indian WHO study examines COVID-19 susceptibility in children versus adults

Now, a group of researchers from India have explored this concept due to the lack of solid evidence and have undertaken a community and population-based serosurveillance study for the coronavirus infection under the World Health Organisation (WHO) Unity umbrella. In this study, participants older than two years old were compared to older adults in terms of seropositivity.

17 Jun 2021

New study pushes the memory clock back over a year

On average the earliest memories that people can recall point back to when they were just two-and-a-half years old, a new study suggests.

14 Jun 2021

Researchers demonstrate an alternative way to produce highly detailed images of the brain

The gold standard in functional brain imaging for over two decades, functional magnetic resonance imaging (fMRI) has transformed the landscape of research and clinical care. Yet, because of its cost and functional limitations, scientists have continued to look for new ways to see into the human brain.

14 Jun 2021

Can rapid antigen tests help screen for COVID-19?

The spread of SARS-CoV-2 is driven by the high proportion of asymptomatic and very mild infections, allowing people to move around and engage in public activity normally. There are many modeling studies that suggest that large-scale screening for the presence of this virus can help curb transmission at this point, from people with few or no symptoms. A new study points out the accuracy of SARS-CoV-2 antigen-detection rapid diagnostic tests for this purpose when used at the point-of-care.

14 Jun 2021

Statins associated with reduced COVID-19 mortality and decreased need for ventilator support

Statins are medications widely used in the management of cardiovascular diseases and metabolic syndrome. Statins help lower serum lipids by blocking HMG-CoA reductase (3-hydroxy-3-methyl-glutaryl-coenzyme A reductase), the rate-limiting enzyme of cholesterol biosynthesis.

11 Jun 2021

Review of COVID-19's long-term effects

In a recent study, Canadian researchers documented the prevalence of post-COVID-19 conditions 4-12 weeks (short-term) and >12 weeks (long-term), by conducting a systematic review of peer-reviewed literature. This work is posted to the medRxiv* preprint server.

9 Jun 2021

Having trouble falling asleep associated with cognitive impairment 14 years later

A study of nearly 2,500 adults found that having trouble falling asleep, as compared to other patterns of insomnia, was the main insomnia symptom that predicted cognitive impairment 14 years later.

9 Jun 2021

Natural products show promise against COVID-19 via iron chelation

Researchers at the University of Catania in Italy investigated whether natural compounds could prevent disease progression. Their study published in the Journal of Clinical Medicine found that iron chelators and protease inhibitors can counteract SARS-CoV-2 infection.

7 Jun 2021

CLARITY News and Research

Further Reading

How women in England faced childbirth in the COVID-19 pandemic

B cell depleting agents can cause altered immune responses to COVID-19 vaccines, suggests study

New neuronal circuit may help control which sensory information is relayed to the auditory cortex

A study on hospitalized COVID-19 patients who received plasma therapy

Experts call on the government to suspend daily contact testing trials in schools

Study: Patients with two SARS-CoV-2 variants are less likely to be asymptomatic compared to control group

Indian WHO study examines COVID-19 susceptibility in children versus adults

New study pushes the memory clock back over a year

Researchers demonstrate an alternative way to produce highly detailed images of the brain

Can rapid antigen tests help screen for COVID-19?

Statins associated with reduced COVID-19 mortality and decreased need for ventilator support

Review of COVID-19's long-term effects

Having trouble falling asleep associated with cognitive impairment 14 years later

Natural products show promise against COVID-19 via iron chelation

International coalition develops classification criteria for 25 subtypes of uveitis

MSU research reveals how the skin's immune cells organize themselves to ward off intruders

Study elucidates the use of anticoagulants to treat bleeding in patients with gastrointestinal cancers

Study could help scientists, policymakers communicate about zoonotic diseases

BMI may not be best obesity indicator to evaluate lung cancer risk, study suggests

From racial justice to dirty air, California’s new AG plots a progressive health care agenda

Latest eBooks

New horizons in drug discovery: High-throughput & target-to-therapy advances

A practical guide to lipid nanoparticle formulation and resizing

Editorial Focus eBook - Spatial and single-cell omics (1st edition)

Industry Focus eBook - Analytical Chemistry (3rd edition)

How Omics Technologies Are Transforming Biological Research and Drug Discovery

How microplastics and bacteria interact to drive antibiotic resistance

Single-cell proteomics: Revealing proteome diversity from cellular heterogeneity to non-canonical biology