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Blood journal publishes GMI-1070 pre-clinical data in sickle cell disease model

GlycoMimetics, Inc., a clinical stage biotechnology company developing a new class of glycobiology based therapies for a broad range of indications, today announced that the journal Blood has published pre-clinical data on the company's lead compound GMI-1070 in a model of sickle cell disease.

29 Sep 2010

Loss of INPP5A gene can predict cutaneous squamous cell carcinoma progression

The loss of a gene known as INPP5A could predict the onset, and track the progression, of an aggressive type of skin cancer, according to a study published today by the Mayo Clinic, Arizona Cancer Center, and the Translational Genomics Research Institute (TGen).

29 Sep 2010

Scientists discover way of shrinking tumours in cancers

Australian and American scientists have found a way of shrinking tumours in certain cancers - a finding that provides hope for new treatments.

29 Sep 2010

Tamir's compounds perform better than Ganciclovir for Cytomegalovirus disease: Study

Tamir Biotechnology, Inc. announced today that scientists supported by the National Institute of Allergy and Infectious Diseases (NIAID) reported test results confirming two of our lead compounds outperformed market leader Roche's drug Ganciclovir in cell culture and plaque reduction assay (the gold standard) for Cytomegalovirus (CMV) disease. Additionally, antiviral activity was also apparent against other human herpesviruses, namely, HSV-1 (cold sores), HSV-2 (genital herpes), and Varicella-Zoster Virus (VZV) (chicken-pox and shingles).

29 Sep 2010

Researchers discover new diagnostic test for prostate cancer

Researchers in England say they have discovered a set of biomarkers that can distinguish prostate cancer from benign prostate disease and healthy tissue with 90 percent accuracy.

From Oxford Gene Technology 29 Sep 2010

Covaris enters co-marketing partnership with Illumina for DNA shearing technologies

Covaris Inc. today announced that it has signed a co-marketing agreement with Illumina, Inc. making Covaris DNA shearing technologies the recommended method of shearing with Illumina next-generation sequencing product lines, including HiSeq, HiScanSQ, and Genome Analyzer.

From Illumina, Inc. 29 Sep 2010

New disposable, microfluidic PDMS device for identification of advanced breast cancer

A new disposable device based on advances in microfluidics may help identify advanced breast cancer patients who are candidates for therapy with the drug trastuzumab (Herceptin). The device is described in the American Institute of Physics' journal Biomicrofluidics.

29 Sep 2010

Saudi FDA approves Apligraf for treatment of diabetic foot ulcers, chronic wounds

Organogenesis, Inc. announced that its Apligraf® bilayered living cellular construct has been approved for the treatment of diabetic foot ulcers and other chronic wounds by the Saudi Food and Drug Authority (SFDA) of the Kingdom of Saudi Arabia. Apligraf is a living cell based product used by physicians to heal chronic wounds in patients in the U.S. and around the world.

29 Sep 2010

NCI awards A&G $1.2M Phase II SBIR grant for development of breast cancer drug candidate

A&G Pharmaceutical announced today that it has received $1.2 million in Phase II Small Business Innovation Research (SBIR) funding from the National Cancer Institute (NCI) for the program, "Novel Targeted Therapy for Breast Cancer," focused on the development of a neutralizing therapeutic antibody against a novel cancer-associated protein, GP88.

29 Sep 2010

Firefly stem cells may help doctors to heal damaged hearts: Research

Stem cells that glow like fireflies could someday help doctors heal damaged hearts without cutting into patients' chests.In his University of Central Florida lab, Steven Ebert engineered stem cells with the same enzyme that makes fireflies glow. The "firefly" stem cells glow brighter and brighter as they develop into healthy heart muscle, allowing doctors to track whether and where the stem cells are working.

29 Sep 2010

IsoRay reports increase revenue for 2010 fiscal year

IsoRay Inc. a medical isotope company and the exclusive manufacturer of Cesium-131 used in internal radiation therapy for the treatment of lung, colon, head and neck, and prostate cancers, ocular melanoma, and other malignant disease through the use of its proprietary radioisotope technology, announced its financial results for the year ended June 30, 2010.

28 Sep 2010

Researchers find genetic variants that cause arthritis in breast cancer patients taking aromatase inhibitors

Mayo Clinic researchers and their international colleagues have discovered genetic variants that lead to severe arthritis for a subset of women when taking aromatase inhibitors to treat their breast cancer. This serious side effect is so painful that many women halt their lifesaving medication. The findings appear today in the online issue of Journal of Clinical Oncology.

28 Sep 2010

Optogenetics helps to restore optimal movement in people with physical disabilities

Researchers at Stanford University were able to use light to induce normal patterns of muscle contraction, in a study involving bioengineered mice whose nerve-cell surfaces are coated with special light-sensitive proteins.

28 Sep 2010

Clinical study results for patient-specific vaccine therapy to treat metastatic melanoma announced

Hoag Memorial Hospital Presbyterian recently announced encouraging clinical study results for patient-specific vaccine therapy to treat metastatic melanoma. The study is ongoing, but the report concludes that patient-specific vaccines can sometimes induce durable complete regression of progressing soft-tissue melanoma metastases, as demonstrated in one particular patient who participated in the trial.

28 Sep 2010

Japanese Patent Office issues patent for ZIOPHARM Oncology's darinaparsin

ZIOPHARM Oncology, Inc. today announced that the Japanese Patent Office has issued a patent, Patent No. 4,571,408, with claims covering pharmaceutical compositions, including oral formulations, of various organic arsenic compounds, including darinaparsin (Zinapar or ZIO-101), and the use of these compositions and the organic arsenic compounds for the treatment of cancer, including as part of a combination therapy.

28 Sep 2010

Women & Infants Hospital receives $2.1M NIH grant to continue work under COBRE for Perinatal Biology

Women & Infants Hospital has recently received a $2.1 million grant from the National Institutes of Health to continue work under the Center of Biomedical Research Excellence for Perinatal Biology. Of the 108 COBREs across the country, Women & Infants is the only one specifically focused on developmental research.

28 Sep 2010

Bayer’s new oral contraceptive receives FDA approval

Bayer HealthCare Pharmaceuticals Inc. today announced that the U.S. Food and Drug Administration has approved a new oral contraceptive, Beyaz (drospirenone / ethinyl estradiol / levomefolate calcium tablets and levomefolate calcium tablets).

28 Sep 2010

NPL, Orla receives fund to improve detection methods for TB

Two UK companies have been awarded joint funding for a research project that could see significant advances in the quest to aid detection and eradication of Tuberculosis (TB), across the world.

28 Sep 2010

Onconova Therapeutics to present Ex-RAD radioprotectant data at RRS Annual Meeting

Onconova Therapeutics, Inc. is presenting new data in five posters and an oral presentation this week summarizing several studies with the company's radioprotectant Ex-RAD- at the 56th Annual Meeting of the Radiation Research Society (RRS), September 25-29 in Maui, Hawaii.

28 Sep 2010

Study may provide new developing approaches to treat age-related osteoporosis

Aging disrupts the balance between bone formation and bone destruction, resulting in osteoporosis, which is characterized by reduced bone mass and increased risk of fracture. Recent data have suggested that this imbalance is a result of a decrease in formation of bone forming osteoblast cells from mesenchymal cells upon aging.

28 Sep 2010

Cell News and Research

Blood journal publishes GMI-1070 pre-clinical data in sickle cell disease model

Loss of INPP5A gene can predict cutaneous squamous cell carcinoma progression

Scientists discover way of shrinking tumours in cancers

Tamir's compounds perform better than Ganciclovir for Cytomegalovirus disease: Study

Researchers discover new diagnostic test for prostate cancer

Covaris enters co-marketing partnership with Illumina for DNA shearing technologies

New disposable, microfluidic PDMS device for identification of advanced breast cancer

Saudi FDA approves Apligraf for treatment of diabetic foot ulcers, chronic wounds

NCI awards A&G $1.2M Phase II SBIR grant for development of breast cancer drug candidate

Firefly stem cells may help doctors to heal damaged hearts: Research

IsoRay reports increase revenue for 2010 fiscal year

Researchers find genetic variants that cause arthritis in breast cancer patients taking aromatase inhibitors

Optogenetics helps to restore optimal movement in people with physical disabilities

Clinical study results for patient-specific vaccine therapy to treat metastatic melanoma announced

Japanese Patent Office issues patent for ZIOPHARM Oncology's darinaparsin

Women & Infants Hospital receives $2.1M NIH grant to continue work under COBRE for Perinatal Biology

Bayer’s new oral contraceptive receives FDA approval

NPL, Orla receives fund to improve detection methods for TB

Onconova Therapeutics to present Ex-RAD radioprotectant data at RRS Annual Meeting

Study may provide new developing approaches to treat age-related osteoporosis

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