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Research roundup: Improving colon cancer screening; disparities in heart care; Medicaid expansion's effect on cities

This report estimated the effect of the Affordable Care Act (ACA) on 14 large and diverse cities: Los Angeles, Chicago, Houston, Philadelphia, Phoenix, Indianapolis, Columbus, Charlotte, Detroit, Memphis, Seattle, Denver, Atlanta, and Miami.

21 Jun 2014

Cubist Pharmaceuticals' SIVEXTRO receives FDA approval for treatment of ABSSSI

Cubist Pharmaceuticals, Inc. announced today the U.S. Food and Drug Administration approved SIVEXTRO (tedizolid phosphate) for the treatment of adult acute bacterial skin and skin structure infections (ABSSSI).

21 Jun 2014

SCLC tumours replicated in mice from patients' CTCs

Scientists have used circulating tumour cells taken from patients with small-cell lung cancer to grow explant tumours in mice that retain the original’s morphological and genetic characteristics.

20 Jun 2014

Telephone-based weight loss intervention is effective in breast cancer treatments

A series of simple telephone calls can make a profound difference in helping women to meet their treatment goals for breast cancer, according to a randomized trial of women who are also obese, published online today in Journal of Clinical Oncology by Dr. Pamela Goodwin of Mount Sinai Hospital and the Lunenfeld-Tanenbaum Research Institute.

20 Jun 2014

First Edition: June 20, 2014

Today's early morning highlights from the major news organizations, including reports about a new poll of showing a majority of those signing up for marketplace plans had been uninsured before and the Obama administration's decision to extend marriage benefits, including family leave, to same-sex couples.

20 Jun 2014

Alternative disposal process in optic nerve cells has implications for neurodegenerative diseases

Biologists have long considered cells to function like self-cleaning ovens, chewing up and recycling their own worn out parts as needed.

20 Jun 2014

Keratoprosthesis restores vision in patients blinded by corneal disease

A new review article in the June issue of Focal Points, a monthly publication of the American Academy of Ophthalmology, calls keratoprosthesis a viable alternative to standard corneal transplantation to help people suffering from corneal blindness.

20 Jun 2014

Researchers review effectiveness of RDTs in diagnosing visceral leishmaniasis

Researchers from the Cochrane Infectious Disease Group, co-ordinated through the editorial base in LSTM, conducted an independent review into the effectiveness of rapid diagnostic tests in diagnosing patients with visceral leishmaniasis (VL), published in The Cochrane Library today.

20 Jun 2014

UCLA study sheds light on the development of lung cancer

UCLA researchers led by Dr. Brigitte Gomperts have discovered the inner workings of the process thought to be the first stage in the development of lung cancer. Their study explains how factors that regulate the growth of adult stem cells that repair tissue in the lungs can lead to the formation of precancerous lesions.

20 Jun 2014

HIV infection emerges among PWID in the Middle East and North Africa

HIV epidemics are emerging among people who inject drugs in several countries in the Middle East and North Africa. Though HIV infection levels were historically very low in the Middle East and North Africa, substantial levels of HIV transmission and emerging HIV epidemics have been documented among people who inject drugs in at least one-third of the countries of this region, according to findings published today in PLOS Medicine.

20 Jun 2014

Researchers discover analgesic mechanism that prevents pain in Buruli ulcer patients

When the body receives an injury to the skin, a signal is sent to the brain, which generates a sensation of pain.

20 Jun 2014

FAK inhibitors prevent ovarian cancer progression

A team of scientists, led by principal investigator David D. Schlaepfer, PhD, professor in the Department of Reproductive Medicine at the University of California, San Diego School of Medicine report that small molecule inhibitors to a protein called focal adhesion kinase (FAK) selectively prevent the growth of ovarian cancer cells as tumor spheroids.

20 Jun 2014

Researchers develop tissue engineered bone grafts for healing large bone defects

Bone is one of the most frequently transplanted tissues. And the demand is rising. Transplants treat large defects like those caused by trauma, complicated fractures, tumour resection or osteoporosis.

20 Jun 2014

NIH receives $10 million grant for research on breast cancer metastasis

The American Cancer Society predicts that 40,000 American women will die from breast cancer this year. Most of those deaths will occur due to cells from the primary tumor that spread to other parts of the body-the process known as metastasis.

20 Jun 2014

Yap1 oncogene drives recurrence and progression of pancreatic cancer

Pancreatic cancer tumors addicted to mutant Kras signaling for their growth and progression have a ready-made substitute to tap if they're ever forced to go cold-turkey on the mutant oncogene, scientists at The University of Texas MD Anderson Cancer Center report in the journal Cell.

20 Jun 2014

New research reveals gene's role in type 1 diabetes

New research describes details of how a diabetes-related gene functions on a biological pathway that affects the release of insulin. The study authors say that finding drugs that act on that pathway may eventually lead to a new treatment for type 1 diabetes.

20 Jun 2014

Researchers shed new light on how gliomas cells migrate in brain and cause devastating tumors

Researchers at the University of Alabama at Birmingham have shed new light on how cells called gliomas migrate in the brain and cause devastating tumors.

20 Jun 2014

Arthritis drug promotes hair growth in hairless man

A man with almost no hair on his body has grown a full head of it after a novel treatment by doctors at Yale University.

20 Jun 2014

Men with prostate cancer achieve stronger muscles and remain active through playing football

Men with prostate cancer aged 43‒74 achieve bigger and stronger muscles, improve functional capacity, gain positive social experiences and the desire to remain active through playing football for 12 weeks.

20 Jun 2014

Susceptibility gene for type 1 diabetes regulates self-destruction of cell's energy factory

A team led by researchers from the Perelman School of Medicine at the University of Pennsylvania found that a susceptibility gene for type 1 diabetes regulates self-destruction of the cell's energy factory. They report their findings this week in Cell.

20 Jun 2014

Medicine News and Research

Research roundup: Improving colon cancer screening; disparities in heart care; Medicaid expansion's effect on cities

Cubist Pharmaceuticals' SIVEXTRO receives FDA approval for treatment of ABSSSI

SCLC tumours replicated in mice from patients' CTCs

Telephone-based weight loss intervention is effective in breast cancer treatments

First Edition: June 20, 2014

Alternative disposal process in optic nerve cells has implications for neurodegenerative diseases

Keratoprosthesis restores vision in patients blinded by corneal disease

Researchers review effectiveness of RDTs in diagnosing visceral leishmaniasis

UCLA study sheds light on the development of lung cancer

HIV infection emerges among PWID in the Middle East and North Africa

Researchers discover analgesic mechanism that prevents pain in Buruli ulcer patients

FAK inhibitors prevent ovarian cancer progression

Researchers develop tissue engineered bone grafts for healing large bone defects

NIH receives $10 million grant for research on breast cancer metastasis

Yap1 oncogene drives recurrence and progression of pancreatic cancer

New research reveals gene's role in type 1 diabetes

Researchers shed new light on how gliomas cells migrate in brain and cause devastating tumors

Arthritis drug promotes hair growth in hairless man

Men with prostate cancer achieve stronger muscles and remain active through playing football

Susceptibility gene for type 1 diabetes regulates self-destruction of cell's energy factory

Everything there is to know about biosimilars eBook

Improving healthcare sustainability through carbon data

Managing vibration in IVF laboratories

A New Approach to Preventing Bladder Cancer Recurrence

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