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Alkermes initiates FORWARD-3 and FORWARD-4 efficacy studies in pivotal clinical program for ALKS 5461

Alkermes plc today announced the initiation of FORWARD-3 and FORWARD-4, two of the three planned phase 3 core efficacy studies in the pivotal clinical program for ALKS 5461, a once-daily, oral investigational medicine with a novel mechanism of action for the adjunctive treatment of major depressive disorder (MDD).

10 Jun 2014

PaxVax partners with UC to develop combination vaccine to prevent genital HSV infections

PaxVax Inc., a specialty vaccine company with a commercial focus on travel and biodefense and a social mission to ensure global access to its vaccines, today announced that it has entered into a research and development collaboration with the University of California, San Diego to develop a combination vaccine to prevent genital herpes simplex virus (HSV) infections.

10 Jun 2014

Auxogyn receives clearance from FDA for Eeva System

Auxogyn, Inc. a leader in women's reproductive health, today announced that its first product, the Eeva System, received clearance from the U.S. Food and Drug Administration through its de novo classification process, a regulatory pathway for select novel, low- to moderate-risk medical devices that are first-of-a-kind.

10 Jun 2014

New therapeutic interventions could render addiction into manageable disease

Neuroscientists agree that abuse of drugs hijacks circuits in the brain that are crucial for decision-making, but society as a whole tends to stigmatize addicted people for lacking self-control.

10 Jun 2014

Professor opens new University of Leicester British Heart Foundation CRC on 11 June 2014

The new University of Leicester British Heart Foundation Cardiovascular Research Centre (CRC) will be officially opened on Wednesday 11 June 2014 by Vice-Chancellor Professor Sir Robert Burgess.

10 Jun 2014

Inovio evaluates responses of immunotherapy product in treating HPV linked head and neck cancer

Inovio Pharmaceuticals, Inc. (NYSE MKT: INO) today announced it has initiated a phase I/IIa clinical trial to evaluate safety, immunogenicity and clinical responses of its immunotherapy product, INO-3112, in treating human papillomavirus (HPV)- associated head and neck cancer.

10 Jun 2014

Synthetic, Enterome partner to study effects of beta-lactam antibiotics on gastrointestinal microflora

Synthetic Biologics, Inc., a developer of novel anti-infective biologic and drug candidates targeting specific pathogens that cause serious infections and diseases, and Enterome Bioscience SA, a pioneer in the development of innovative disease management solutions based on a deep understanding of the gut microbiome, today announced that they have entered into an agreement to conduct metagenomic research on the effects of beta-lactam antibiotics on the gastrointestinal microflora (microbiome) of human patients.

10 Jun 2014

Research on viral RNA may help scientists develop treatments against infectious diseases

In an article published in the scientific journal Nature, a University of Colorado School of Medicine researcher and colleagues explain how RNA molecules found in certain viruses mimic the shape of other molecules as part of a strategy to 'hijack' the cell and make more viruses.

10 Jun 2014

Groundbreaking molecular imaging agent developed to trace advanced prostate cancer

Anti-androgen hormonal therapy, also called chemical castration, can be an important defense against further disease progression for patients with prostate cancer that has traveled and grown in other areas, or metastasized-but some cases simply do not respond to this treatment.

10 Jun 2014

Researchers reveal mysterious behavior of individual cells using radioluminescence microscopy

With a new molecular imaging system powerful enough to peer down to 20-micrometer resolution, researchers can now use radioluminescence to examine the characteristics of single, unconnected cells. The result is a fascinating picture of diversity among cells previously assumed to behave the same, revealed researchers at the Society of Nuclear Medicine and Molecular Imaging's 2014 Annual Meeting.

10 Jun 2014

REM sleep disorder: A sign of impending neurodegenerative disease

How many millions of people suffer from sleep disturbance? One sleep disorder in particular, called REM behavior disorder, could be a sign of impending neurodegenerative disease, including Parkinson's and dementia, say scientists presenting their research at the Society of Nuclear Medicine and Molecular Imaging's 2014 Annual Meeting.

10 Jun 2014

Researchers solve structure of key protein that drives DNA copying in plasmids

Staph infections that become resistant to multiple antibiotics don't happen because the bacteria themselves adapt to the drugs, but because of a kind of genetic parasite they carry called a plasmid that helps its host survive the antibiotics.

10 Jun 2014

State highlights: Improving chronic care in Las Vegas; standoff over Medicaid in N.C.

Now, Las Vegas is emerging as a test of how much a community can improve chronically poor health by expanding insurance coverage and using models of medical care pioneered in healthier places. "We are a prime example of what people see as problematic about the American healthcare system," said Larry Matheis, the former longtime head of the Nevada State Medical Assn. "That makes a lot of the ideas in health reform very attractive. … The challenge is going to be figuring out how to make it all work" (Levey, 6/7).

10 Jun 2014

Children who undergo complex imaging tests may have increased risk of cancer

Children with heart disease are exposed to low levels of radiation during X-rays, which do not significantly raise their lifetime cancer risk.

10 Jun 2014

Ohio State doctors treat heart failure patients with new wireless, implantable hemodynamic monitor

Doctors at The Ohio State University Wexner Medical Center are the first in the country to begin treating some heart failure patients with a new wireless, implantable hemodynamic monitor that was just approved by the U.S. Food and Drug Administration. The monitor will help physicians observe pulmonary artery pressures, optimize treatment and prevent hospitalizations.

10 Jun 2014

Targeting popular kids for fighting obesity may not be effective

In the fight against teenage obesity, some researchers have proposed targeting popular teens, in the belief that such kids would have an outsize influence on their peers.

10 Jun 2014

Tobacco smoking linked to nearly 2 million deaths among Asian adults in recent years

A new study estimates that tobacco smoking has been linked to approximately 2 million deaths among adult men and women in Asia in recent years and predicts a rising death toll.

10 Jun 2014

Protein may be key to maintaining health of aging blood stem cells

A protein may be the key to maintaining the health of aging blood stem cells, according to work by researchers at the Icahn School of Medicine at Mount Sinai recently published online in Stem Cell Reports.

10 Jun 2014

Combined MMRV vaccine slightly increases risk of febrile seizures in children

The combined measles-mumps-rubella-varicella (MMRV) vaccine shows a slightly increased risk of febrile seizures in children, compared with the previously separate vaccines for MMR and varicella (chickenpox) (MMR+V), according to an article in CMAJ (Canadian Medical Association Journal).

10 Jun 2014

Combined chemo and radionuclide therapy stops neuroendocrine tumors

Advanced cancer of the neuroendocrine system can lead to dismal prognoses, but a novel therapy is packing a punch by uniting powerful radionuclide treatment and chemotherapy drugs, revealed researchers at the Society of Nuclear Medicine and Molecular Imaging's 2014 Annual Meeting.

10 Jun 2014

Medicine News and Research

Alkermes initiates FORWARD-3 and FORWARD-4 efficacy studies in pivotal clinical program for ALKS 5461

PaxVax partners with UC to develop combination vaccine to prevent genital HSV infections

Auxogyn receives clearance from FDA for Eeva System

New therapeutic interventions could render addiction into manageable disease

Professor opens new University of Leicester British Heart Foundation CRC on 11 June 2014

Inovio evaluates responses of immunotherapy product in treating HPV linked head and neck cancer

Synthetic, Enterome partner to study effects of beta-lactam antibiotics on gastrointestinal microflora

Research on viral RNA may help scientists develop treatments against infectious diseases

Groundbreaking molecular imaging agent developed to trace advanced prostate cancer

Researchers reveal mysterious behavior of individual cells using radioluminescence microscopy

REM sleep disorder: A sign of impending neurodegenerative disease

Researchers solve structure of key protein that drives DNA copying in plasmids

State highlights: Improving chronic care in Las Vegas; standoff over Medicaid in N.C.

Children who undergo complex imaging tests may have increased risk of cancer

Ohio State doctors treat heart failure patients with new wireless, implantable hemodynamic monitor

Targeting popular kids for fighting obesity may not be effective

Tobacco smoking linked to nearly 2 million deaths among Asian adults in recent years

Protein may be key to maintaining health of aging blood stem cells

Combined MMRV vaccine slightly increases risk of febrile seizures in children

Combined chemo and radionuclide therapy stops neuroendocrine tumors

Everything there is to know about biosimilars eBook

Improving healthcare sustainability through carbon data

Managing vibration in IVF laboratories

A New Approach to Preventing Bladder Cancer Recurrence

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