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Parkinson’s disease discoveries

Genes that affect the immune system and link it to Parkinson’s disease have been uncovered. This paves the way for new drug development in Parkinson’s disease – a serious, degenerative disease of the nerves that leads to tremors and muscle stiffness and eventually complete loss of movements. There is currently no cure for PD.

31 Aug 2010

CORDIS reports positive results from 10-year follow-up of CYPHER Sirolimus-eluting coronary stent study

Cordis Corporation, a worldwide leader in the development and manufacture of interventional vascular technology, announced today at European Society of Cardiology in Stockholm that the results of follow-up tests undertaken ten years after the first patient was treated with a CYPHER(R) Sirolimus-eluting coronary stent have proven outstanding long-term efficacy and safety and were published earlier this year in "JACC: Cardiovascular Interventions".

31 Aug 2010

Social interaction reduces physical damage to brain by heart attack: Research

A new study in mice shows how social support can help minimize some of the worst physical damages to the brain caused by a heart attack.

31 Aug 2010

Final regulation to aid Veterans exposed to herbicides published in 'Federal Register'

Veterans exposed to herbicides while serving in Vietnam and other areas will have an easier path to access quality health care and qualify for disability compensation under a final regulation that will be published on August 31, 2010 in the Federal Register by the Department of Veterans Affairs (VA). The new rule expands the list of health problems VA will presume to be related to Agent Orange and other herbicide exposures to add two new conditions and expand one existing category of conditions.

31 Aug 2010

Advanced Life Sciences scientific publication demonstrates triterpenoids' potential as anticancer agents

Advanced Life Sciences Holdings, Inc.,a biopharmaceutical company engaged in the discovery, development and commercialization of novel drugs in the therapeutic areas of infection, oncology and respiratory diseases, today announced the publication of a research paper in the journal Bioorganic and Medicinal Chemistry Letters that reports data using the Company's core triterpenoid platform technology in the discovery and development of new cancer therapeutic agents.

31 Aug 2010

Phase 3 EINSTEIN-DVT clinical trial data can transform deep vein thrombosis treatment

Johnson & Johnson Pharmaceutical Research & Development, announced today that the investigational, oral anticoagulant rivaroxaban successfully demonstrated non-inferiority compared to the standard of care for the prevention of recurrent venous thromboembolism (VTE) in patients with acute symptomatic deep vein thrombosis (DVT), with a comparable safety profile.

31 Aug 2010

Bioheart's MyoCell adult stem cell therapy shows effective for heart failure patients: Study

Bioheart, Inc., The mission of the Cell Therapy Foundation is to improve public health through the support of effective adult stem cell research and education. The Foundation aims to promote basic and applied knowledge, processes and cell therapies.

31 Aug 2010

New hybrid proteins may lead to better gene replacement and editing therapies

An Iowa State University team of researchers has developed a type of hybrid proteins that can make double-strand DNA breaks at specific sites in living cells, possibly leading to better gene replacement and gene editing therapies.

31 Aug 2010

MGH scientists develop new microfluidic tool for accurate isolation of neutrophils

A team led by Massachusetts General Hospital (MGH) scientists has developed a new microfluidic tool for quickly and accurately isolating neutrophils - the most abundant type of white blood cell - from small blood samples, an accomplishment that could provide information essential to better understanding the immune system's response to traumatic injury. The system, described in a Nature Medicine paper that received advance online release, also can be adapted to isolate almost any type of cell.

31 Aug 2010

Research on trypanosomes can open way for African sleeping sickness drug development

Trypanosomes are parasites responsible for many human and animal diseases, primarily in tropical climates. One disease these parasites cause, African sleeping sickness, results from the bite of infected tsetse flies, putting over 60 million Africans at risk in 36 sub-Saharan countries. The recent 1998-2001 sleeping sickness epidemics in South Sudan, Angola, Democratic Republic of Congo and Uganda killed tens of thousands of people and resulted in over a half million infected individuals.

31 Aug 2010

Disruption of structural component in heart muscle cells occurs before decline in heart function

The disruption of a structural component in heart muscle cells, which is associated with heart failure, appears to occur even before heart function starts to decline, according to a new study by researchers at the University of Iowa Roy J. and Lucille A. Carver College of Medicine.

31 Aug 2010

Advanced Cell Technology updates transdifferentiation plans to enhance regenerative medicine

Advanced Cell Technology, Inc. provides an update today on its plans to utilize its transdifferentiation platform to enhance regenerative medicine.

31 Aug 2010

RXR-alpha protein helps to protect pigment cells from invasive melanoma: Research

New research on how skin cancer begins has identified adjacent cancer cells that scientists are calling "co-conspirators" in the genesis of melanoma, in findings that could someday hold the key to predicting, preventing and stopping this hard-to-treat cancer before it spreads.

31 Aug 2010

Amino acid arginine vital in fighting infection

Richard Lamb and his post doctoral fellow Virginie Mieulet, in the Faculty of Medicine & Dentistry, may be able to explain why proper nutrition is so vital in fighting infection.

31 Aug 2010

Cell Therapy Foundation analysis calls for funding in medical research

Some of the most promising medical research conducted to treat diseases of the brain, heart, and circulatory system is moving too slowly to help millions of patients, according to the Cell Therapy Foundation, which advocates the use of adult stem cells to dramatically impact and improve the condition of patients who suffer from a variety of conditions.

31 Aug 2010

Cognizant Communication launches 'Cell Medicine' open access journal

A new and unique journal on cell transplantation aimed at helping translate laboratory findings into clinical applications is being launched by Cognizant Communication Corporation as a companion journal to Cell Transplantation. Cell Medicine, an online-only, open access journal, publishes research papers that promise to have direct clinical relevance. The journal is freely accessible at: http://www.ingentaconnect.com/content/cog/cm.

30 Aug 2010

Reactivation of CDX2 gene may halt progression of colon cancer

The intestines have to work properly if we are to benefit from the food we eat. Digestive juices must be secreted, the food broken down into smaller components and then transported through the gut wall and onwards to muscles and organs. The lining of the gut is coated in epithelial cells, a specialised layer that produces mucous and hormones while keeping dangerous bacteria and toxins at bay. Close contact with pathogenic microbes and toxins means that the epithelial cells may mutate to form cancer.

30 Aug 2010

ThermoGenesis sells two BioArchive Systems to HealthBanks Biotech

ThermoGenesis Corp., a leading supplier of innovative products and services that process and store adult stem cells, said today it has sold two BioArchive® Systems to HealthBanks Biotech Company, Ltd..

30 Aug 2010

BioMarin's BMN-701 receives FDA orphan drug designation for treatment of Pompe disease

BioMarin Pharmaceutical Inc. announced today that it has received orphan drug designation from the U.S. Food and Drug Administration (FDA) for BMN-701, a novel fusion of insulin-like growth factor 2 and alpha glucosidase (IGF2-GAA) in development for the treatment of Pompe disease. An investigational new drug application (IND) for BMN-701 has been submitted, investigational material has been manufactured and a Phase I/II study is expected to start in the first quarter of 2011.

30 Aug 2010

Perfadex improves survival in lung tranplant patients: Study

A recently published study in The Journal of Heart and Lung Transplantation shows that the patients who are most seriously ill before lung tranplantation have better one-year survival when Perfadex is used as the preservation solution for donor lungs compared with UW solution. Furthermore, the patients who received lungs preserved in Perfadex ran a significantly lower risk of being affected by rejection reactions requiring treatment.

30 Aug 2010

Cell News and Research

Parkinson’s disease discoveries

CORDIS reports positive results from 10-year follow-up of CYPHER Sirolimus-eluting coronary stent study

Social interaction reduces physical damage to brain by heart attack: Research

Final regulation to aid Veterans exposed to herbicides published in 'Federal Register'

Advanced Life Sciences scientific publication demonstrates triterpenoids' potential as anticancer agents

Phase 3 EINSTEIN-DVT clinical trial data can transform deep vein thrombosis treatment

Bioheart's MyoCell adult stem cell therapy shows effective for heart failure patients: Study

New hybrid proteins may lead to better gene replacement and editing therapies

MGH scientists develop new microfluidic tool for accurate isolation of neutrophils

Research on trypanosomes can open way for African sleeping sickness drug development

Disruption of structural component in heart muscle cells occurs before decline in heart function

Advanced Cell Technology updates transdifferentiation plans to enhance regenerative medicine

RXR-alpha protein helps to protect pigment cells from invasive melanoma: Research

Amino acid arginine vital in fighting infection

Cell Therapy Foundation analysis calls for funding in medical research

Cognizant Communication launches 'Cell Medicine' open access journal

Reactivation of CDX2 gene may halt progression of colon cancer

ThermoGenesis sells two BioArchive Systems to HealthBanks Biotech

BioMarin's BMN-701 receives FDA orphan drug designation for treatment of Pompe disease

Perfadex improves survival in lung tranplant patients: Study

What are the challenges of cell line development? eBook

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