Cell News and Research

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BioMarin Pharmaceutical acquires ZyStor Therapeutics, furthers development of ZC-701 for Pompe disease

BioMarin Pharmaceutical Inc. announced today that it has acquired ZyStor Therapeutics, Inc. (ZyStor), a privately-held biotechnology company developing enzyme replacement therapies (ERT) for the treatment of lysosomal storage disorders. ZyStor's lead product candidate is ZC-701, a novel fusion of insulin-like growth factor 2 and alpha glucosidase (IGF2-GAA) in development for Pompe disease.

18 Aug 2010

ImmunoCellular Therapeutics raises $6.5 million in second quarter 2010

ImmunoCellular Therapeutics today announced second quarter results for the period ended June 30, 2010. The Company utilized $1.13 million of cash in its operations during the quarter. The increase in net burn is reflective of increased personnel costs as well as increase in Research and Development costs associated with the planned phase II clinical trial for ICT-107.

18 Aug 2010

Aastrom Bioscience fourth quarter net loss decreases to $0.18 per share

Aastrom Biosciences, Inc., the leading developer of autologous cellular therapies for the treatment of severe cardiovascular diseases, today reported operating results for the fourth quarter and fiscal year ended June 30, 2010.

18 Aug 2010

Economically dependent males likely to cheat female partners: Research

The more economically dependent a man is on his female partner, the more likely he is to cheat on her, according to research to be presented at the 105th Annual Meeting of the American Sociological Association."But for women, economic dependency seems to have the opposite effect: the more dependent they are on their male partners, the less likely they are to engage in infidelity," said Christin Munsch, a sociology Ph.D. candidate at Cornell University, and author of the study, "The Effect of Relative Income Disparity on Infidelity for Men and Women."

17 Aug 2010

Tecan, Miltenyi Biotec partner to develop magnetic bead technology based automated solutions for cell biology

Tecan is working with Miltenyi Biotec, a leading provider of cell biology solutions, to develop a range of automated solutions for cell biology, based on the powerful MACS(R) Magnetic bead technology. This new agreement will allow customers to benefit from the advanced capabilities of Tecan's Freedom EVO(R) liquid handling platforms when performing a wide range of separation, cultivation and analysis processes for cells and biomolecules.

From Tecan 17 Aug 2010

Adults who have Internet access at home prone to romantic relationships: Research

Adults who have Internet access at home are much more likely to be in romantic relationships than adults without Internet access, according to research to be presented at the 105th Annual Meeting of the American Sociological Association.

17 Aug 2010

Rice receives Defense Threat Reduction Agency grant to develop genomic test for cultivated pathogens

Researchers at Rice University have won federal support to develop a genomic test that can quickly determine whether a disease outbreak is caused by a natural pathogen or one that was grown in a lab by terrorists.

17 Aug 2010

Study discovers multiple effects of SSRIs on cells

A new discovery about selective serotonin reuptake inhibitors (SSRIs) suggests that these drugs, which are used to treat mental health disorders like depression and anxiety, have multiple effects on our cells. In a research report published in the August 2010 issue of GENETICS, researchers used yeast cells to identify secondary drug targets or pathways affected by SSRIs. Such secondary pathways could help explain why different people taking the same drug may experience different effects, and could also lead to new types of drugs altogether.

17 Aug 2010

NSF awards Georgia Institute of Technology $3 million for stem cell bio-manufacturing research program

The National Science Foundation (NSF) has awarded $3 million to the Georgia Institute of Technology to fund a unique research program on stem cell bio-manufacturing. The program is specifically focused on developing engineering methods for stem cell production, in order to meet the anticipated demand for stem cells. The award comes through the NSF's Integrative Graduate Education and Research Traineeship (IGERT) Program, which supports innovation in graduate education in fields that cross academic disciplines and have broad societal impact.

17 Aug 2010

Nanoparticle-based gene silencing system inhibits angiogenesis process in tumor growth

A protein associated with cancer progression when abundant inside of tumors also unexpectedly regulates the creation of new blood vessels that feed the tumor outside, a research team led by scientists at The University of Texas MD Anderson Cancer Center reports in the August edition of Cancer Cell.

17 Aug 2010

MMV joins Pool for Open Innovation against neglected tropical diseases

The Medicines for Malaria Venture (MMV) today became the first product development partnership (PDP) to contribute intellectual property to the Pool for Open Innovation against Neglected Tropical Diseases. MMV joins GlaxoSmithKline (GSK), Alnylam Pharmaceuticals, and the Massachusetts Institute of Technology (MIT) in contributing to the Pool, which is administered by BIO Ventures for Global Health (BVGH).

17 Aug 2010

Studies provide evidence for new approach to MRSA vaccines

Two recent studies provide evidence for a new approach to vaccines to prevent infections caused by drug-resistant Staphylococcus aureus -- better known as MRSA - the leading cause of skin and soft tissue, bloodstream and lung infections in the United States. One demonstrates a way to counteract the bacteria's knack for evading the immune system. The other shows how to disrupt the germ's tissue-damaging mechanism.

17 Aug 2010

Ancient discovery holds key to joint tissue regeneration

Osteoarthritis is a crippling disease worldwide, with an estimated eight million sufferers in the UK alone. It has been described as like "wearing a suit of rusty armour," with unrelenting, razor-like pain.

17 Aug 2010

Human induced pluripotent stem cells help to treat Parkinson’s disease: Research

Researchers at the Buck Institute for Age Research have successfully used human induced pluripotent stem cells (iPSCs) to treat rodents afflicted with Parkinson's Disease (PD). The research, which validates a scalable protocol that the same group had previously developed, can be used to manufacture the type of neurons needed to treat the disease and paves the way for the use of iPSC's in various biomedical applications. Results of the research, from the laboratory of Buck faculty Xianmin Zeng, Ph.D., are published August 16, 2010 in the on-line edition of the journal Stem Cells.

17 Aug 2010

Scientists create nanoscale coating to eradicate methicillin resistant bacteria

Building on an enzyme found in nature, researchers at Rensselaer Polytechnic Institute have created a nanoscale coating for surgical equipment, hospital walls, and other surfaces which safely eradicates methicillin resistant Staphylococcus aureus (MRSA), the bacteria responsible for antibiotic resistant infections.

17 Aug 2010

Key scientific work in Cardio3 BioSciences' C-Cure stem cell heart failure treatment published in JACC

Cardio3 BioSciences, a leading Belgian biotechnology company specialising in regenerative therapies for the treatment of cardiovascular disease, today announces that the key scientific work underlying its lead pharmaceutical product C-Cure(R), a revolutionary stem cell treatment for heart failure, has been published in the Journal of the American College of Cardiology (JACC). The findings were described as "landmark work" in the accompanying editorial in today's publication.

17 Aug 2010

BAC, Octapharma enter licence agreement for G-CSF CaptureSelect custom affinity ligand

BAC BV, the leading provider of antibody-based affinity purification technology, today announced that it has entered into a licence agreement with Octapharma (Lachen, Switzerland), an independent, global provider of human proteins for life-threatening diseases.

17 Aug 2010

Scientists experiment with three proteins that impact preadipocytes contribute to fat cell determination

Just what causes the birth of a human fat cell is a mystery, but scientists using mathematics to tackle the question have come up with a few predictions about the proteins that influence this process.The research is intended to increase understanding of how and why preadipocytes, or pre-fat cells, either lie dormant, copy themselves or turn into fat. But the findings eventually could lead to a way to freeze these early cells in their current state before they can ever become the basis of fat tissue, according to Ohio State University researchers.

17 Aug 2010

Scientists identify possible therapeutic strategy for reducing leukemia risk from chemotherapy

A UCSF-led team has discovered at least one key reason why blood stem cells are susceptible to developing the genetic mutations that can lead to adult leukemia. Their finding also may explain, they say, why some other age-related hematological disorders develop.The study, reported in "Cell Stem Cell" and reviewed in Cell Stem Cell and Cell, opens a new frontier for studying the molecular underpinnings of adult leukemia.

17 Aug 2010

Study finds abnormal expression of miRNAs can contribute to human diseases

Researchers at Tufts University School of Medicine and Tufts Medical Center have identified an RNA sequence that promotes increased numbers of specific microRNAs (miRNAs), molecules that regulate cell growth, development, and stress response. The discovery helps researchers understand the links between miRNA expression and disease, including heart disease and cancer. The findings are published in the August 13 issue of Molecular Cell.

17 Aug 2010

Cell News and Research

BioMarin Pharmaceutical acquires ZyStor Therapeutics, furthers development of ZC-701 for Pompe disease

ImmunoCellular Therapeutics raises $6.5 million in second quarter 2010

Aastrom Bioscience fourth quarter net loss decreases to $0.18 per share

Economically dependent males likely to cheat female partners: Research

Tecan, Miltenyi Biotec partner to develop magnetic bead technology based automated solutions for cell biology

Adults who have Internet access at home prone to romantic relationships: Research

Rice receives Defense Threat Reduction Agency grant to develop genomic test for cultivated pathogens

Study discovers multiple effects of SSRIs on cells

NSF awards Georgia Institute of Technology $3 million for stem cell bio-manufacturing research program

Nanoparticle-based gene silencing system inhibits angiogenesis process in tumor growth

MMV joins Pool for Open Innovation against neglected tropical diseases

Studies provide evidence for new approach to MRSA vaccines

Ancient discovery holds key to joint tissue regeneration

Human induced pluripotent stem cells help to treat Parkinson’s disease: Research

Scientists create nanoscale coating to eradicate methicillin resistant bacteria

Key scientific work in Cardio3 BioSciences' C-Cure stem cell heart failure treatment published in JACC

BAC, Octapharma enter licence agreement for G-CSF CaptureSelect custom affinity ligand

Scientists experiment with three proteins that impact preadipocytes contribute to fat cell determination

Scientists identify possible therapeutic strategy for reducing leukemia risk from chemotherapy

Study finds abnormal expression of miRNAs can contribute to human diseases

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