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New method efficiently converts stem cells to endothelial cells for cardiovascular research

The innermost layer of blood vessels is formed by endothelial cells, which in turn play a role in the development of diseases of the cardiovascular system.

31 Jul 2024

Wildlife species show high SARS-CoV-2 exposure linked to human activity

Researchers found SARS-CoV-2 RNA in six wildlife species and higher seroprevalence in high human activity areas. Seven new human-to-animal transmission events of the Omicron variant were identified.

30 Jul 2024

Targeting oncogenic transcription factors to develop potential new cancer treatments

A new study from the University of Michigan Health Rogel Cancer Center furthers research that suggests the potential of developing new cancer treatments to target oncogenic transcription factors by indirectly affecting their ability to access enhancer DNA in chromatin.

30 Jul 2024

Review highlights the interplay of TGF-β and HIPPO pathways in liver regeneration and disease

The liver's ability to communicate with other organs is crucial for maintaining homeostasis, particularly through signaling pathways.

30 Jul 2024

ACE technology enhances single-cell protein detection with advanced signal amplification

Since the 1950s, researchers have used a famous method invented by Wallace Coulter known as "flow cytometry" to characterize different types of immune cells in research studies and in blood samples from human individuals.

30 Jul 2024

Garlic as a potent weapon against atherosclerosis

Researchers identified garlic's potential to treat atherosclerosis by regulating ferroptosis and reducing lipid peroxidation, offering a safer alternative to current treatments.

29 Jul 2024

Advancing hepatic cell carcinoma treatment through mitochondrial DNA targeting

Hepatic cell carcinoma (HCC), the fifth most prevalent malignancy worldwide and the fourth leading cause of cancer-related mortality, poses significant therapeutic challenges.

29 Jul 2024

Understanding iron overload in β-thalassemia: Mechanisms, diagnosis, and treatments

β-Thalassemia is a genetic disorder characterized by reduced or absent synthesis of the beta chains of hemoglobin, leading to ineffective erythropoiesis and severe anemia.

29 Jul 2024

Cytomegalovirus in breast milk linked to changes in infant growth and gut microbiome

Research shows human cytomegalovirus (CMV) reactivation in breast milk affects milk composition, infant gut microbiome, and growth, with potential impacts on neonatal health.

28 Jul 2024

Understanding Global Harmonization of Regulatory CMC within Veterinary Medicine with Tammy Newbold

In this interview, News Med talks to Tammy Newbold about Global Harmonization of Regulatory CMC within Veterinary Medicine.

From DSI, a PLG Company 26 Jul 2024

Understanding the epigenetic regulation of hepatic stellate cells in NAFLD

Non-alcoholic fatty liver disease (NAFLD) has emerged as a leading cause of chronic liver disease worldwide, affecting approximately 38% of the global population from 2016 to 2019.

25 Jul 2024

Associations between gut microbes and Alzheimer’s disease

Researchers reviewed existing data on the role of the gut microbiome in Alzheimer’s disease (AD) pathogenesis.

24 Jul 2024

Exploring non-coding RNAs as regulators of notch signaling in breast cancer

Breast cancer (BC) remains one of the most challenging cancers to treat, primarily due to its heterogeneity and propensity for metastasis.

23 Jul 2024

Unraveling the role of TAL1 and miR-146b-5p in T-cell acute lymphoblastic leukemia

T-cell acute lymphoblastic leukemia (T-ALL) is an aggressive form of leukemia that arises from the malignant transformation of T-cell progenitors.

23 Jul 2024

Deciphering the role of RET in cancer and breakthroughs in targeted treatments

Xueqing Hu , Ujjwol Khatri , Tao Shen , and Jie Wu, at University of Oklahoma Health Sciences Center, USA, provides a comprehensive review of the role of the RET (REarranged during Transfection) receptor tyrosine kinase in cancer development and the advancements in RET-targeted cancer therapies.

19 Jul 2024

Breakthrough in aging research: Blocking IL-11 extends lifespan and improves health in mice

Blocking IL-11 signaling extends lifespan and healthspan in mice, reducing age-related metabolic decline, frailty, and cancer incidence.

18 Jul 2024

Study uncovers how OTX2 drives aggressive childhood brain cancer

In a report published in Nature Cell Biology, researchers at Baylor College of Medicine, Texas Children's Hospital, the University of Manitoba and collaborating institutions revealed an unexpected way in which the protein OTX2 drives the progression of medulloblastoma – the most common aggressive childhood brain cancer.

18 Jul 2024

Study finds dairy cows vulnerable to flu strains from birds, humans, and pigs

Researchers compared the distribution of sialic acid receptors in the respiratory tract and mammary glands of dairy cattle naturally infected with the highly pathogenic avian influenza A(H5N1) virus.

18 Jul 2024

Study links circadian rhythm disruption to obesity and diabetes

Disruption of circadian rhythms and clock gene expression is linked to adverse metabolic health outcomes, including obesity and diabetes. Further research is needed to understand these relationships and their implications for treatment and prevention.

17 Jul 2024

Harnessing cell's natural delivery system for targeted drug delivery

Each cell in the body has its own unique delivery system that scientists are working on harnessing to move revolutionary biological drugs - molecules like proteins, RNA and combinations of the two - to specific diseased parts of the body.

17 Jul 2024

Transcription News and Research

New method efficiently converts stem cells to endothelial cells for cardiovascular research

Wildlife species show high SARS-CoV-2 exposure linked to human activity

Targeting oncogenic transcription factors to develop potential new cancer treatments

Review highlights the interplay of TGF-β and HIPPO pathways in liver regeneration and disease

ACE technology enhances single-cell protein detection with advanced signal amplification

Garlic as a potent weapon against atherosclerosis

Advancing hepatic cell carcinoma treatment through mitochondrial DNA targeting

Understanding iron overload in β-thalassemia: Mechanisms, diagnosis, and treatments

Cytomegalovirus in breast milk linked to changes in infant growth and gut microbiome

Understanding Global Harmonization of Regulatory CMC within Veterinary Medicine with Tammy Newbold

Understanding the epigenetic regulation of hepatic stellate cells in NAFLD

Associations between gut microbes and Alzheimer’s disease

Exploring non-coding RNAs as regulators of notch signaling in breast cancer

Unraveling the role of TAL1 and miR-146b-5p in T-cell acute lymphoblastic leukemia

Deciphering the role of RET in cancer and breakthroughs in targeted treatments

Breakthrough in aging research: Blocking IL-11 extends lifespan and improves health in mice

Study uncovers how OTX2 drives aggressive childhood brain cancer

Study finds dairy cows vulnerable to flu strains from birds, humans, and pigs

Study links circadian rhythm disruption to obesity and diabetes

Harnessing cell's natural delivery system for targeted drug delivery

Event guide: 4th Extra-Hepatic Lipid-Based Nanoparticles Delivery Summit eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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