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Alkermes initiates pivotal clinical development program for treatment of MDD

Alkermes plc today announced the initiation of the pivotal clinical development program for ALKS 5461, a once-daily, oral investigational medicine with a novel mechanism of action for the adjunctive treatment of major depressive disorder (MDD).

6 Mar 2014

Safeguard Scientifics reports net income of $24 million for fourth quarter 2013

Safeguard Scientifics, Inc. today announced fourth quarter and full-year 2013 financial results. For the three months ended December 31, 2013, Safeguard's net income was $24.0 million, or $1.10 per share, compared to net loss of $10.8 million, or $0.51 per share for the same period in 2012. For the year ended December 31, 2013, Safeguard's net loss was $35.5 million, or $1.66 per share, compared to $39.4 million, or $1.88 per share for the same period in 2012.

6 Mar 2014

Research to identify exact mechanisms behind preterm birth and fetal brain injury

An inflammatory protein that triggers a pregnant mouse's immune response to an infection or other disease appears to cause brain injury in her fetus, but not the premature birth that was long believed to be linked with such neurologic damage in both rodents and humans, new Johns Hopkins-led research suggests.

6 Mar 2014

Scientists develop reliable way of detecting prostate and bladder cancers

A new licence announced today between the University of Surrey and Randox, will bring to market a new test that will help with the early detection of prostate and bladder cancers.

From Randox Laboratories Ltd. 6 Mar 2014

New guidelines developed to help patients better understand cancer consultations

The experiences of doctors, patients and carers of initial cancer consultations have informed new guidelines developed at the University of Leicester, in collaboration with University Hospitals of Leicester NHS Trust and Imperial College London, to help patients better understand their cancer consultations.

6 Mar 2014

ASTRO white paper recommends specific guidance to follow in the delivery of HDR brachytherapy

The American Society for Radiation Oncology has issued a new white paper, "A review of safety, quality management, and practice guidelines for high-dose-rate brachytherapy," that recommends specific guidance to follow in the delivery of high-dose-rate (HDR) brachytherapy to improve quality and patient safety, according to the manuscript published in the March-April 2014 print issue of Practical Radiation Oncology, the official clinical practice journal of ASTRO.

6 Mar 2014

New drug is effective against superbug MRSA

"I routinely call hospitals and request their yearly antibiotic susceptibility testing data," said Washington University in St. Louis' Timothy Wencewicz. "The log might say, for example, that they've treated hundreds of patients for Acinetobacter baumanni, a bacterium brought into U.S. hospitals by soldiers wounded in the Iraq war, with 30 different antibiotics.

6 Mar 2014

Study finds long-term reduction in mortality for young men who undergo radical prostatectomy

More than 230,000 men will be diagnosed with prostate cancer this year in the United States, but determining their course of treatment remains a source of considerable debate. A new study by researchers from Uppsala University Hospital, Sweden, Harvard School of Public Health and colleagues—which draws from one of the few randomized trials conducted to directly address this issue—finds a substantial long-term reduction in mortality for men with localized cancer who undergo a radical prostatectomy.

6 Mar 2014

UCLA experts offer tips to help protect colon health

With colorectal cancer the second leading cause of cancer death, it's a great time to take a look at the health of your colon.

6 Mar 2014

Viewpoints: Obama's budget punts on entitlements; Medicaid debate rankles states

There is a lesson in this unexpected juxtaposition nevertheless: No nation can safely base its tax and spending plans on inflexible commitments. Political life, both domestic and international, is too unpredictable. Yet U.S. government spending is mostly on autopilot. The government is scheduled to lay out $3.8 trillion this fiscal year - 70 percent of which will go to mandatory-spending programs, chiefly Social Security, Medicare, Medicaid and interest on the federal debt. Mr. Obama's plan for fiscal 2015 does not change this; it would increase overall spending slightly, paying for it with selected tax increases, while shifting money among priorities here and there. But these tweaks would take place within the same 30 percent of discretionary spending that the current budget contains (3/4).

6 Mar 2014

Calcium and vitamin D supplements can improve cholesterol profiles in postmenopausal women

Calcium and vitamin D supplements after menopause can improve women's cholesterol profiles. And much of that effect is tied to raising vitamin D levels, finds a new study from the Women's Health Initiative just published online in Menopause, the journal of The North American Menopause Society.

6 Mar 2014

New study uses Lumosity games to detect subtle cognitive impairments in patients with cirrhosis

A new study from the University of Washington has found that performance on Lumosity games can distinguish between patients with cirrhosis of the liver, pre-cirrhotic patients, and healthy controls. The study used Lumosity games as psychometric tests to detect subtle cognitive impairments in patients with cirrhosis. The study is published in the March issue of the American Journal of Gastroenterology.

6 Mar 2014

Verastem presents preliminary data from VS-6063 Phase 1 trial in Japanese patients with solid tumors

Verastem, Inc., focused on discovering and developing drugs to treat cancer by the targeted killing of cancer stem cells, today presented preliminary data from an ongoing First-in-Asia Phase 1 trial of VS-6063 in Japanese patients with advanced solid tumors, including one patient with mesothelioma. The Phase 1 study assessed the safety and pharmacokinetics of single agent VS-6063.

5 Mar 2014

Treating cystic fibrosis: an interview with Simon Bedson, Senior Vice President and International General Manager at Vertex

Cystic fibrosis is a rare, life-shortening genetic disease for which there is no cure. It affects more than 75,000 people worldwide. In CF, thick, sticky mucus blocks the passages in many organs, leading to a variety of symptoms. In particular, mucus builds up and clogs airways in the lungs making it easier for bacteria to grow.

5 Mar 2014

POZEN reports total revenue of $4.7 million for fourth quarter 2013

POZEN Inc., a pharmaceutical company committed to transforming medicine that transforms lives, today announced results for the fourth quarter and year ended December 31, 2013.

5 Mar 2014

Minimally invasive surgery outcomes show favorable results in low back pain patients

Beaumont research findings published in the February online issue of Spine shows that patients who have a low back surgery called minimally invasive transforaminal lumbar interbody fusion, end up better off in many ways than patients who have more invasive surgery to alleviate debilitating pain.

5 Mar 2014

Research shows depletion of cholesteryl ester impairs prostate cancer aggressiveness

Researchers have discovered a link between prostate cancer aggressiveness and the accumulation of a compound produced when cholesterol is metabolized in cells, findings that could bring new diagnostic and treatment methods.

5 Mar 2014

$Meta-analysis study shows association between BTMs s-CTX, s-PINP and risk of future fractures$

Meta-analysis study shows association between BTMs s-CTX, s-PINP and risk of future fractures

A new study by an International Osteoporosis Foundation (IOF) and International Federation of Clinical Chemistry and Laboratory Medicine (IFCC) scientific working group summarizes the clinical performance of serum procollagen type I N propeptide (s-PINP) and serum C-terminal cross-linking telopeptide of type I collagen (s-CTX) in fracture risk prediction in untreated individuals in prospective cohort studies.

5 Mar 2014

Transfusion Evidence Library provides evidence-based information for blood transfusion-related research

A recent systematic review conducted by the Collaboration for Evidence Based Healthcare in Africa on evidence-based healthcare treatment (EBHC) has shown that EBHC teaching and learning strategies on the African continent should focus on implementing multifaceted, clinically integrated approaches and assessment.

5 Mar 2014

New study shows male hormones play important role; may enhance IVF therapy in women

Several fertility clinics across the country are beginning to administer testosterone, either through a patch or a gel on the skin, to increase the number of eggs produced by certain women undergoing in vitro fertilization (IVF).

5 Mar 2014

Medicine News and Research

Alkermes initiates pivotal clinical development program for treatment of MDD

Safeguard Scientifics reports net income of $24 million for fourth quarter 2013

Research to identify exact mechanisms behind preterm birth and fetal brain injury

Scientists develop reliable way of detecting prostate and bladder cancers

New guidelines developed to help patients better understand cancer consultations

ASTRO white paper recommends specific guidance to follow in the delivery of HDR brachytherapy

New drug is effective against superbug MRSA

Study finds long-term reduction in mortality for young men who undergo radical prostatectomy

UCLA experts offer tips to help protect colon health

Viewpoints: Obama's budget punts on entitlements; Medicaid debate rankles states

Calcium and vitamin D supplements can improve cholesterol profiles in postmenopausal women

New study uses Lumosity games to detect subtle cognitive impairments in patients with cirrhosis

Verastem presents preliminary data from VS-6063 Phase 1 trial in Japanese patients with solid tumors

Treating cystic fibrosis: an interview with Simon Bedson, Senior Vice President and International General Manager at Vertex

POZEN reports total revenue of $4.7 million for fourth quarter 2013

Minimally invasive surgery outcomes show favorable results in low back pain patients

Research shows depletion of cholesteryl ester impairs prostate cancer aggressiveness

Meta-analysis study shows association between BTMs s-CTX, s-PINP and risk of future fractures

Transfusion Evidence Library provides evidence-based information for blood transfusion-related research

New study shows male hormones play important role; may enhance IVF therapy in women

Everything there is to know about biosimilars eBook

Improving healthcare sustainability through carbon data

Managing vibration in IVF laboratories

A New Approach to Preventing Bladder Cancer Recurrence

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