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Smoking turns on genes

Smoking tobacco is no longer considered sexy, but it may prove a permanent turn on for some genes.

26 Aug 2007

Avastin approved in Europe for advanced lung cancer

Avastin (bevacizumab), Roche's innovative anti-cancer drug, was approved today in Europe for the first-line treatment of patients with advanced non-small cell lung cancer (NSCLC), in combination with platinum-based chemotherapy.

26 Aug 2007

Blocking angiogenesis signaling from inside cell may lead to serious health problems

Angiogenesis inhibitors that block a tumor's development of an independent blood supply have been touted as effective cancer fighters that result in fewer side effects than traditional chemotherapy.

24 Aug 2007

Link between diabetes and high-fructose corn syrup in soft drinks

Researchers have found new evidence that soft drinks sweetened with high-fructose corn syrup (HFCS) may contribute to the development of diabetes, particularly in children.

24 Aug 2007

Networking in living cells may hold key to fighting diseases

Scientists in Manchester are working to change the social habits of living cells an innovation that could bring about cleaner and greener fuel and help fight diseases such as cancer and diabetes.

From The University of Manchester 24 Aug 2007

Binding up iron in the brain to combat Parkinson's and Alzheimer's

Duke University chemists are developing ways to bind up iron in the brain to combat the neurological devastation of Parkinson's and Alzheimer's diseases.

24 Aug 2007

Nanoparticle drug delivery system for brain tumor therapy shows promise

A nanoparticle drug delivery system designed for brain tumor therapy has shown promising tumor cell selectivity in a novel cell culture model devised by University of Nottingham scientists.

24 Aug 2007

Potential new leukemia drug

In a new study, Danilo Perrotti and colleagues from Ohio State University, Columbus, show that treatment with a drug known as FTY720 prevents disease in a mouse model of many leukemias caused by the cancer protein BCR-ABL (nearly all cases of blast crisis chronic myeloid leukemia [CML-BC] and some cases of acute lymphocytic leukemia [ALL]).

24 Aug 2007

Light may play a much more important role in bacterial life than has previously thought

The bacteria that cause brucellosis can sense light and use the information to regulate their virulence, according to a study in the August 24 issue of the journal Science.

24 Aug 2007

Nuclear nanocapsules to target tiny tumors

Rice University chemists have found a way to package some of nature's most powerful radioactive particles inside DNA-sized tubes of pure carbon -- a method they hope to use to target tiny tumors and even lone leukemia cells.

24 Aug 2007

In the junk lies treasure when it comes to DNA

Three micro RNA genes appear to be key partners of protective gene p53; their loss is linked to common type of lung cancer

24 Aug 2007

New options in treating pigmentation disorders

Melanocytes are not the only cells responsible for differences in skin coloration. New research from the University of Cincinnati (UC) has shown that some of the most basic cells on the skin's surface influence pigment production and help regulate skin coloration.

24 Aug 2007

Discovery of new gene family essential for embryonic development

The family controls the expression of genes crucial for stem cell maintenance and differentiation, and the results may contribute sig-nificantly to the understanding of the development of cancer.

24 Aug 2007

First large-scale study of proteins inside human cells called Jurkat T cells

The study, which appears in the August issue of Molecular & Cellular Proteomics, could lead to a better understanding of how proteins inside a specific type of cell work together and may pave the way for future detailed studies of how proteins work in other types of cells.

24 Aug 2007

All eukaryotic kinases share 1 common set of substrates

Kinase mediated phosphorylation is generally recognised as the major regulator of virtually all metabolic activities in eukaryotic cells including proliferation, gene expression, motility, vesicular transport and programmed cell death.

24 Aug 2007

Insight into autism's origin in the brain

In the first study of its kind, researchers have discovered that in autistic individuals, connections between brain cells may be deficient within single regions, and not just between regions, as was previously believed.

23 Aug 2007

Rapamycin study is first stage in development of new treatment

Rapamycin isn't your ordinary potential anti-cancer drug…It had a long and somewhat exotic history before undergoing preclinical (laboratory-based) studies at St. Jude as part of a national Pediatric Preclinical Testing Program (PPTP) investigation of its anticancer activity.

23 Aug 2007

Study helps predict anesthesia-linked risks for children with chest tumors

Children with mediastinal masses - tumors in their chest outside the lungs - are at special risk for developing breathing problems when they undergo anesthesia. These young patients are of special concern to clinicians who must anesthetize them as part of their medical treatment.

23 Aug 2007

Cancer stem cell scientists get $1.7 million to develop new leukemia drugs

"Modern cancer treatments fail to get to the root of the cancer - the stem cells - which is why many cancers recur despite aggressive treatment."

23 Aug 2007

Kidney removed through belly button

Surgeons specializing in laparoscopic procedures at UT Southwestern Medical Center have successfully removed a patient's kidney by performing a unique nephrectomy entirely through the belly button.

23 Aug 2007