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Glioblastoma multiforme patients treated with experimental vaccine show improved survival

Patients with recurrent glioblastoma multiforme treated with an experimental vaccine made from the patient's own resected tumor tissue showed an improved survival compared with historical patients who received the standard of care alone, according to an analysis of a phase 2 trial of this vaccine that was recently published in the journal Neuro-Oncology and accompanied by an editorial highlighting the importance of the trial.

16 Dec 2013

First Edition: December 16, 2013

Today's headlines include findings from an Associated Press poll probing Americans thoughts about the health law.

16 Dec 2013

Experimental drug that targets macrophages decreases cancer's growth

An experimental drug that targets macrophages, a type of immune cells, in the microenvironment surrounding the lethal brain tumor glioblastoma multiforme decreased the cancer's growth and extended survival of laboratory mice with the cancer, scientists will report on Tuesday Dec. 17, at the American Society for Cell Biology annual meeting in New Orleans.

16 Dec 2013

Queen's University professor wins Gold Award for Innovation for research on male infertility

A Queen's University Professor has received international recognition for her research into male infertility.

16 Dec 2013

Stem cell technology: an interview with Professor Igor Slukvin, University of Wisconsin-Madison and scientific founder of CDI and Cynata

Stem cells have a potential to develop into multiple cell types and divide without limit to replenish cells in human body throughout the life of individual.

16 Dec 2013

Data show that HCV genotype-1 infected patients may benefit from faldaprevir

Data show that Boehringer Ingelheim’s second-generation protease inhibitor faldaprevir, when used in combination with pegylated interferon and ribavirin, was effective even with the presence of naturally-occurring mutant variants of the hepatitis C virus, such as the NS3 Q80K polymorphism

16 Dec 2013

Drug abuse appears to foster brain changes that resemble schizophrenia

Teens who were heavy marijuana users -- smoking it daily for about three years -- had abnormal changes in their brain structures related to working memory and performed poorly on memory tasks, reports a new Northwestern Medicine- study.

16 Dec 2013

Research roundup: Long-term care use varies dramatically by state; health spending slowdown explained

In 2012, about 58,500 paid, regulated long-term care services providers served about 8 million people in the United States. Long-term care services were provided by 4,800 adult day services centers, 12,200 home health agencies, 3,700 hospices, 15,700 nursing homes, and 22,200 assisted living and similar residential care communities. Each day in 2012, there were 273,200 participants enrolled in adult day services centers, 1,383,700 residents in nursing homes, and 713,300 residents in residential care communities; in 2011, about 4,742,500 patients received services from home health agencies, and 1,244,500 patients received services from hospices. Provider sectors differed in ownership, and average size and supply varied by region (Harris-Kojetin et al., 12/12).

16 Dec 2013

Robotic trolley system helps overcome falling fear for patients who recovering from stroke, brain injury

The risk and fear of falling often affects patients who are recovering from a stroke, spinal cord or brain injury, and orthopaedic injuries, and that fear may inhibit their progress in rehabilitation.

16 Dec 2013

Adding drug to presurgery chemotherapy improves results for women with triple-negative breast cancer

The I-SPY 2 trial, an innovative, multidrug, phase II breast cancer trial, has yielded positive results with the first drug to complete testing in the trial. Adding the chemotherapy carboplatin and the molecularly targeted drug veliparib to standard presurgery chemotherapy improved outcomes for women with triple-negative breast cancer, according to results from the I-SPY 2 trial presented here at the 2013 San Antonio Breast Cancer Symposium, held Dec. 10-14.

16 Dec 2013

NIH Stroke Trials Network includes UC San Diego Health System as grant recipient

A network of 25 nationally recognized stroke centers has been created to rapidly address the three core features of stroke research and care: prevention, treatment and recovery. The regional coordinating centers, working with nearby satellite facilities, will span the country and have teams of researchers representing every stroke-related medical specialty, with the primary goal of bringing new therapies and strategies to the stroke community more rapidly.

16 Dec 2013

Pregnant women, infants should avoid unpasteurized milk products, urge pediatricians

Pregnant women, infants and young children should avoid raw or unpasteurized milk and milk products and only consume pasteurized products, according to a new policy statement from the American Academy of Pediatrics.

16 Dec 2013

Findings could point the way to new vaccines to prevent Mycobacterium tuberculosis

The lung lesions in an individual infected with tuberculosis are surprisingly variable and independent of each other, despite whether the patient has clinically active or latent disease, according to a new animal study led by researchers at the University of Pittsburgh School of Medicine. The findings, published online today in Nature Medicine, could point the way to new vaccines to prevent the hard-to-treat infection.

16 Dec 2013

Research suggests new way of treating asthma in obese people

Research conducted at Boston Children's Hospital indicates that obesity might cause asthma via factors in the immune system and suggests a new way of treating asthma in obese people—who often respond poorly to standard asthma medications. The study, conducted in a mouse model of asthma and in human lung fluid, was published online Dec. 15 by Nature Medicine.

16 Dec 2013

Researchers identify new method to predict outcomes in heart failure patients

Researchers at the George Washington University School of Medicine and Health Sciences (SMHS) and Johns Hopkins University School of Medicine have identified a new method to determine whether a patient's heart will fail, which in the future may help physicians better treat patients and tailor therapeutic interventions.

16 Dec 2013

Public, patients and doctors confuse palliative care with end of life care, says new review

A new review says palliative care's association with end of life has created an "identity problem" that means the majority of patients facing a serious illness do not benefit from treatment of the physical and psychological symptoms that occur throughout their disease.

16 Dec 2013

Study could lead towards a personalised medicine for chemoresistant lymphomata

To date, tests have only been carried out on cells, but a piece of research conducted by the Department of Genetics at the UPV/EHU's Faculty of Medicine in collaboration with MD Anderson and the CNIO is opening up the door for the treatment of lymphoma types that have a lower survival rate. The study of the molecular characteristics of the tumours would enable molecules that are altered in a specific way to be identified and turned into new therapeutic targets that would improve the prognosis of patients with chemoresistant lymphomata.

16 Dec 2013

CHOP scientist receives 2013 E. Donnall Thomas Prize for scientific, clinical research in hemophilia

Katherine A. High, M.D., of The Children's Hospital of Philadelphia (CHOP) was honored for her trailblazing scientific and clinical research in the bleeding disorder hemophilia when she received the 2013 E. Donnall Thomas Prize from the American Society of Hematology (ASH) at its annual meeting on Dec. 9 in New Orleans.

15 Dec 2013

UTHealth professor wins Founders' Laurel Award for exceptional service in the field of medical education

Arthur L. Day, M.D., professor of neurosurgery at The University of Texas Health Science Center at Houston and a neurosurgeon at the Mischer Neuroscience Institute at Memorial Hermann-Texas Medical Center, has received one of the top honors awarded by the Congress of Neurological Surgeons.

14 Dec 2013

Scientists reveal how two genes interact to kill broad range of cancer cells

Scientists from Virginia Commonwealth University Massey Cancer Center have revealed how two genes interact to kill a wide range of cancer cells. Originally discovered by the study's lead investigator Paul B. Fisher, M.Ph., Ph.D., the genes known as mda-7/IL-24 and SARI could potentially be harnessed to treat both primary and metastatic forms of brain, breast, colon, lung, ovary, prostate, skin and other cancers.

14 Dec 2013

Medicine News and Research

Glioblastoma multiforme patients treated with experimental vaccine show improved survival

First Edition: December 16, 2013

Experimental drug that targets macrophages decreases cancer's growth

Queen's University professor wins Gold Award for Innovation for research on male infertility

Stem cell technology: an interview with Professor Igor Slukvin, University of Wisconsin-Madison and scientific founder of CDI and Cynata

Data show that HCV genotype-1 infected patients may benefit from faldaprevir

Drug abuse appears to foster brain changes that resemble schizophrenia

Research roundup: Long-term care use varies dramatically by state; health spending slowdown explained

Robotic trolley system helps overcome falling fear for patients who recovering from stroke, brain injury

Adding drug to presurgery chemotherapy improves results for women with triple-negative breast cancer

NIH Stroke Trials Network includes UC San Diego Health System as grant recipient

Pregnant women, infants should avoid unpasteurized milk products, urge pediatricians

Findings could point the way to new vaccines to prevent Mycobacterium tuberculosis

Research suggests new way of treating asthma in obese people

Researchers identify new method to predict outcomes in heart failure patients

Public, patients and doctors confuse palliative care with end of life care, says new review

Study could lead towards a personalised medicine for chemoresistant lymphomata

CHOP scientist receives 2013 E. Donnall Thomas Prize for scientific, clinical research in hemophilia

UTHealth professor wins Founders' Laurel Award for exceptional service in the field of medical education

Scientists reveal how two genes interact to kill broad range of cancer cells

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

Improving healthcare sustainability through carbon data

Managing vibration in IVF laboratories

A New Approach to Preventing Bladder Cancer Recurrence

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