Immune Response News and Research

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A promising, effective vaccine for common respiratory disease

Skin vaccination using a microneedle patch that contains the inactivated respiratory syncytial virus (RSV) and a compound that stimulates immune responses to the virus has been found to enhance protection against this serious disease and reduce inflammation in the body after exposure to the virus, according to a study led by Georgia State University.

18 Dec 2018

Russian scientists identify molecular 'switch' that could be target for treatment of allergic asthma

A team of Russian scientists identified the role of the interleukin-6 molecule in the development of allergic asthma. Now it can be a new target for the treatment of this disease. The results are published in Frontiers in Immunology.

17 Dec 2018

Researchers reveal how key transcription factor keeps the immune system in check

Our immune systems defend our bodies against dangerous invaders and help clean up when damage is done. But if our bold protectors are left unsupervised, they sometimes do their jobs too well and end up harming healthy tissues.

17 Dec 2018

Recurrence of urinary tract infection may depend on bacterial strain, study shows

Genetically diverse bacterial strains that cause urinary tract infections differ in their ability to trigger protective immune responses in mice, potentially explaining why these infections frequently recur in many patients, according to a study published December 13 in the open-access journal PLOS Pathogens by Thomas Hannan and Scott Hultgren of Washington University School of Medicine, and colleagues.

14 Dec 2018

Study shows septin proteins detect and kill gut pathogen, Shigella

Using state-of-the art technologies to image human cells and study infection at the level of a single bacterial cell, the research team, led by the London School of Hygiene & Tropical Medicine, has uncovered the strongest evidence yet that septins take Shigella prisoner.

13 Dec 2018

Butantan Institute signs collaboration agreement with MSD to develop dengue vaccines

On Wednesday, December 12, 2018, Brazil's Butantan Institute signed a collaboration agreement with Merck Sharp & Dohme (MSD) to develop dengue vaccines.

12 Dec 2018

Scientists discover cellular mechanism that triggers pneumonia in humans

The situation is relatively common, especially in winter. You come down with the flu, which lasts longer than usual. A few days later, you discover you have pneumonia.

10 Dec 2018

Insights into protein-protein interactions and methods for designing small molecule inhibitors

Proteins are polymers of amino acids that are linked by peptide bonds and they are one of the major classes of bio-molecules existing in a living organism. Proteins are involved in various cellular functions and events like cell signaling, cell adhesion, metabolic reactions, in the generation of immune response and many more.

10 Dec 2018

VCU researchers test vaccine against opioid abuse

Virginia Commonwealth University researchers are testing a vaccine against opioid abuse developed by the Scripps Research Institute in California. The vaccine is meant to block the effects of heroin and fentanyl in patients with opioid use disorder.

7 Dec 2018

New way of controlling HIV latency to completely eradicate the virus

A new study suggests that a genetic switch that causes latent HIV inside cells to begin to replicate can be manipulated to completely eradicate the virus from the human body. Cells harboring latent HIV are "invisible" to the natural defenses of the immune system.

7 Dec 2018

Study sheds new light on microtubule binding proteins and microtubule dynamics

When bacteria or viruses enter the body, proteins on their surfaces are recognized and processed to activate T cells, white blood cells with critical roles in fighting infections.

6 Dec 2018

Researchers aim to demystify bladder immunity

We know that the bladder is a poorly understood organ, critical for storing metabolic waste. What we don’t know is how this unique environment impacts bladder immunity to common diseases such as urinary tract infections and bladder cancer.

6 Dec 2018

New CU Boulder study shows how spinal injury impacts circadian rhythms

In the hours and days following a spinal cord injury, the gears that control the body's internal clocks fall profoundly out of sync, impacting body temperature, hormone fluctuation, immunity and the timing of a host of other bodily processes, according to new University of Colorado Boulder research.

5 Dec 2018

Montana State-led research project wins $10 million grant to prevent bat-borne diseases

In an effort to prevent some of the world's most lethal diseases, an international research team spanning five continents and led by Montana State University will study bats in Australia, Bangladesh, Madagascar and Ghana.

5 Dec 2018

Eliminating microglia can reverse some aspects of stress sensitization, study shows

Using an animal model of chronic stress, researchers at The Ohio State University have shown that the immune cells of the brain, called microglia, hold unique signatures of chronic stress that leave the animal more sensitive to future stressful experiences, evident by increased anxiety and immune responses.

4 Dec 2018

CAR-T cell therapy appears to be promising option for treating large B-cell lymphoma

So-called CAR-T cell therapy is a promising option for treating around a fifth of patients with diffuse large B-cell lymphoma.

4 Dec 2018

Researchers aim to develop a functional cure for HIV using therapeutic vaccines

EU-funded researchers are leading efforts to develop a functional cure for HIV using innovative therapeutic vaccines to halt the progression of the devastating virus, increase the availability and affordability of treatment, and improve patients' quality of life.

30 Nov 2018

Scientists create mini-placenta's to study early stages of pregnancy

Researchers at the University of Cambridge have used organoid culture techniques to create a cellular model of the early stages of the placenta.

29 Nov 2018

Researchers find how skin cancer cells avoid attack by the immune system

Researchers at the Mainz University Medical Center discovered a new signal pathway employed by skin cancer cells to avoid attack by the immune system. In an animal model and through analysis of human tissue samples, Dr. Toszka Bohn, Dr. Steffen Rapp and Professor Tobias Bopp were able to demonstrate the significant role played by a specific protein called ICER.

29 Nov 2018

Platelets grown from stem cells could reduce the reliance on donated platelets

Researchers have developed a way to grow human platelets in the laboratory from stem cells derived from fat tissue. The achievement, reported today in the journal Blood, suggests manufactured platelets could eventually reduce the reliance on donated platelets to help patients with cancer and other disorders.

29 Nov 2018

Immune Response News and Research

A promising, effective vaccine for common respiratory disease

Russian scientists identify molecular 'switch' that could be target for treatment of allergic asthma

Researchers reveal how key transcription factor keeps the immune system in check

Recurrence of urinary tract infection may depend on bacterial strain, study shows

Study shows septin proteins detect and kill gut pathogen, Shigella

Butantan Institute signs collaboration agreement with MSD to develop dengue vaccines

Scientists discover cellular mechanism that triggers pneumonia in humans

Insights into protein-protein interactions and methods for designing small molecule inhibitors

VCU researchers test vaccine against opioid abuse

New way of controlling HIV latency to completely eradicate the virus

Study sheds new light on microtubule binding proteins and microtubule dynamics

Researchers aim to demystify bladder immunity

New CU Boulder study shows how spinal injury impacts circadian rhythms

Montana State-led research project wins $10 million grant to prevent bat-borne diseases

Eliminating microglia can reverse some aspects of stress sensitization, study shows

CAR-T cell therapy appears to be promising option for treating large B-cell lymphoma

Researchers aim to develop a functional cure for HIV using therapeutic vaccines

Scientists create mini-placenta's to study early stages of pregnancy

Researchers find how skin cancer cells avoid attack by the immune system

Platelets grown from stem cells could reduce the reliance on donated platelets

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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