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Antibody-toxin compound shows compelling antitumor activity in non-Hodgkin lymphomas patients

A toxin linked to a targeted monoclonal antibody has shown "compelling" antitumor activity in patients with non-Hodgkin lymphomas who were no longer responding to treatment, according to a report from Dana-Farber Cancer Institute.

11 Dec 2013

GW Pharmaceuticals receives U.S. patent for treating glioma

GW Pharmaceuticals plc, a biopharmaceutical company focused on discovering, developing and commercializing novel therapeutics from its proprietary cannabinoid product platform, announced that the United States Patent and Trademark Office (USPTO) has issued a Notice of Allowance for U.S. Application Serial Number 12/996,124, a patent which covers the use of cannabinoids for treating glioma.

11 Dec 2013

Study looks at brain imaging data in veterans who suffered combat-related head injuries

In preliminary findings, Saint Louis University researchers report that veterans who suffered blast injuries have changes in brain tissue that are still apparent in images years after the blast. The data, presented at the annual meeting of the Radiological Society of North America, represents a small but intriguing look at brain imaging in those who suffered combat-related head injuries.

11 Dec 2013

Pharmacyclics presents ibrutinib trial data for B-cell malignancies at ASH meeting

Pharmacyclics, Inc. today announced results of 40 clinical, non-clinical and pre-clinical presentations on ibrutinib (IMBRUVICA™) at the 55TH Annual meeting of the American Society of Hematology (ASH) held in New Orleans, Dec 7 - 10, 2013.

11 Dec 2013

High cholesterol fuels growth and spread of breast Cancer

Researchers at Duke Medicine conclude that high cholesterol may make breast cancer worse when they found that a byproduct of cholesterol functions like the hormone estrogen, leading to increases in the growth and spread of breast cancer. Studies have previously shown the link between obesity and breast cancer, but the exact cause of the increased risk had not been identified.

11 Dec 2013

Beta-carotene: An important and safe precursor for vitamin A

A Case Western Reserve University School of Medicine study in the November 22 issue of Journal of Biological Chemistry, explains how vitamin A is generated from beta carotene, its dietary precursors. The discovery sheds new light into how beta carotene’s enzymes are utilized differently contributing to the vitamin’s production. This insight will help guide solutions for vitamin A deficiency, a global public health problem affecting more than half of all countries, according to the World Health Organization.

11 Dec 2013

Baxter seeks FDA approval of OBI-1 for adults with acquired hemophilia A

Baxter International Inc. today announced that the company has submitted a biologics license application (BLA) to the U.S. Food and Drug Administration (FDA) for the approval of OBI-1, a recombinant antihemophilic porcine sequence factor VIII, in patients with acquired hemophilia A.

From Baxter International Inc. 11 Dec 2013

Discovery could lead to new way to combat cancer

One way to defeat an opponent is to cut off its supply lines. Tumors are no different. The supply lines for tumors are the blood vessels that ferry oxygen and nutrients to the cells. Restricting the blood vessels that feed tumor cells can shrink the tumor. A cross-institutional international team of scientists recently discovered a new, important step of the process that grows new blood vessels, a discovery that could lead to a new way to combat cancer.

11 Dec 2013

Duke University receives $2.9M grant to develop HIV vaccine candidate

Duke University has received a grant of up to $2.9 million from the Bill & Melinda Gates Foundation to produce an HIV vaccine candidate that will be tested in humans.

10 Dec 2013

Endocrinologist suggests parents to check their child's blood sugar more often during holidays

Indulgences abound during the holidays—from family gatherings to parties with friends and even stockings stuffed with goodies from Santa. For children with diabetes, overindulging on the delicacies of the season could result in more than a stomach ache, it could mean a trip to the emergency room.

10 Dec 2013

Tips to relieve dry skin

Dry skin is a common problem during the winter and its effects can be painful - causing the skin to flake, itch, crack and even bleed. Yet dermatologists say there are ways people can find relief by implementing a few changes to their daily lives.

10 Dec 2013

FoundationOne Heme identifies clinically actionable genomic alterations in multiple myeloma cases

Foundation Medicine today announced new data from a pilot study demonstrating that its fully informative genomic profile for hematologic malignancies, FoundationOne Heme, identified both novel and previously reported clinically actionable genomic alterations in multiple myeloma cases. These data were presented in an oral presentation titled Pilot Study To Evaluate The Prevalence Of Actionable Oncogenic Mutations In Patients With Relapsed Refractory Multiple Myeloma (abstract number 755) by Alexander Lesokhin, M.D., medical oncologist, Memorial Sloan-Kettering Cancer Center, at the 55th American Society of Hematology Annual Meeting in New Orleans.

10 Dec 2013

Scientists unveil novel piece of puzzle of cancer cell DNA repair mechanisms

Research with a Finnish background facilitates the development of more effective cancer medication. Cancer cells have an exceptional ability to repair damage to their DNA caused during uncontrolled cell division.

10 Dec 2013

COC launches first clinic on London's Harley Street for specialised cancer treatment

Care Oncology Clinic, an independent, private organisation providing oncology treatments, announces today the launch of its first clinic on London's Harley Street. Delivered by leading oncologists and palliative care doctors, the clinic is the first of its kind, specifically set up to offer a specialised cancer treatment by targeting the energy requirements of cancer cells using existing medicines that are already licensed for this purpose, have an acceptable safety profile and are low cost. Designed for patients for whom the standard oncology treatment regime is not available, viable, tolerable or providing benefit, this is a new option for treating these cancer patients.

10 Dec 2013

Eurofins successfully completes genetic and forensic research project on twins

Eurofins Scientific, one of the global leaders in Genomics Services, announces a research breakthrough in genetic discrimination between identical monozygotic twins.

10 Dec 2013

Article outlines new approach for reviewing potential downsides of screening recommendation

Screening to detect medical conditions has become standard practice for many diseases, but insufficient attention has been paid to the potential for harm, according to research conducted at the University of North Carolina.

10 Dec 2013

Many Americans still tend to avoid addressing own end-of-life issues

During the past two decades, high-profile legal cases surrounding end-of-life decisions have received widespread attention in the United States, prompting increased media focus and numerous debates on the subject.

10 Dec 2013

State highlights: Union, Calif. Hospital Assn. at odds over organization, ballot issues; Ind. hospital cuts worry nurses; N.C. Medicaid overhaul changes

Duane Dauner, president of the California Hospital Assn., emailed the group's board in September with a warning: The leader of the state's largest health care workers' union had told him that if hospitals did not pave the way for the organizing of 20,000 workers, the union would launch ballot measures taking aim at hospital pricing and executive pay. But negotiations on organizing agreements between the two sides stalled. In November, the union, SEIU-United Healthcare Workers West, filed two initiatives for the 2014 ballot that would limit hospital prices and cap executive compensation at nonprofit hospitals (Mason, 12/6).

10 Dec 2013

Studies expose high prevalence of epilepsy and other neurological disorders in US Veterans

Three studies coming out of the American Epilepsy Society's 67th Annual Meeting in Washington DC expose the high prevalence of epilepsy and other neurological disorders in US Veterans who served in Operation Enduring Freedom, Operation Iraqi Freedom and Operation New Dawn. The research conducted from these studies indicate that veterans are at a particularly high risk for traumatic brain injury, post traumatic stress disorder, psychological non-epileptic seizures and epileptic seizure diagnoses.

10 Dec 2013

Drugs that enhance oxidative stress kill rhabdomyosarcoma tumor cells

Drugs that enhance a process called oxidative stress were found to kill rhabdomyosarcoma tumor cells growing in the laboratory and possibly bolstered the effectiveness of chemotherapy against this aggressive tumor of muscle and other soft tissue. The findings are the latest from the St. Jude Children's Research Hospital-Washington University Pediatric Cancer Genome Project and appear in the December 9 edition of the scientific journal Cancer Cell.

10 Dec 2013

Medicine News and Research

Antibody-toxin compound shows compelling antitumor activity in non-Hodgkin lymphomas patients

GW Pharmaceuticals receives U.S. patent for treating glioma

Study looks at brain imaging data in veterans who suffered combat-related head injuries

Pharmacyclics presents ibrutinib trial data for B-cell malignancies at ASH meeting

High cholesterol fuels growth and spread of breast Cancer

Beta-carotene: An important and safe precursor for vitamin A

Baxter seeks FDA approval of OBI-1 for adults with acquired hemophilia A

Discovery could lead to new way to combat cancer

Duke University receives $2.9M grant to develop HIV vaccine candidate

Endocrinologist suggests parents to check their child's blood sugar more often during holidays

Tips to relieve dry skin

FoundationOne Heme identifies clinically actionable genomic alterations in multiple myeloma cases

Scientists unveil novel piece of puzzle of cancer cell DNA repair mechanisms

COC launches first clinic on London's Harley Street for specialised cancer treatment

Eurofins successfully completes genetic and forensic research project on twins

Article outlines new approach for reviewing potential downsides of screening recommendation

Many Americans still tend to avoid addressing own end-of-life issues

State highlights: Union, Calif. Hospital Assn. at odds over organization, ballot issues; Ind. hospital cuts worry nurses; N.C. Medicaid overhaul changes

Studies expose high prevalence of epilepsy and other neurological disorders in US Veterans

Drugs that enhance oxidative stress kill rhabdomyosarcoma tumor cells

Everything there is to know about biosimilars eBook

Improving healthcare sustainability through carbon data

Managing vibration in IVF laboratories

A New Approach to Preventing Bladder Cancer Recurrence

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