Immune Response News and Research

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Researchers report first randomized trial results of 'kick and kill' approach to treat HIV

Researchers have reported the results of the first randomized clinical trial to test a novel strategy involving waking up and then killing the 'sleeping' HIV that is hiding in the body using an experimental approach known as 'kick and kill'.

24 Jul 2018

UVA researchers discover how obesity may trigger harmful inflammation

New research from the University of Virginia School of Medicine explains why obesity causes harmful inflammation that can lead to diabetes, clogged arteries and other health problems. Doctors may be able to use this knowledge to battle these chronic diseases and others driven by damaging inflammation.

24 Jul 2018

New study provides important clues to developing more effective Ebola vaccines

Scientists conducting the first comprehensive study of key immune system cells - collected from West African Ebola survivors that kill Ebola infected cells have made a surprising discovery that provides important clues to developing effective vaccines against the infection.

24 Jul 2018

Study finds new enzyme that lays foundations for allergic immune response

While in search of the causes of allergies and asthma, a chance discovery has yielded new clues: researchers led by Dr Marcus Peters have ascertained that the enzyme guanylate cyclase in cells lays the foundations for the type of immune response.

23 Jul 2018

Study uncovers new protein complex that shields broken DNA ends

Scientists have made a major discovery about how cells repair broken strands of DNA that could have huge implications for the treatment of cancer.

19 Jul 2018

Mother's microbiome determines offspring's risk of developing autism

The risk of developing autism-spectrum disorders is determined by the mother's microbiome - the collection of microorganisms that naturally live inside us - during pregnancy, new research from the University of Virginia School of Medicine suggests.

18 Jul 2018

Deleting single gene in gut bacteria affects metabolism, reduces weight gain in mice

Scientists have found that deleting a single gene in a particular strain of gut bacteria causes changes in metabolism and reduced weight gain in mice, according to a study in the journal eLife.

18 Jul 2018

New review examines cannabinoids' potential for direct treatment of cancer

Previous research has shown that cannabinoids can help lessen side effects of anti-cancer therapies. Now a new British Journal of Pharmacology review has examined their potential for the direct treatment of cancer.

18 Jul 2018

Early childhood adversity increases sensitivity of the body's immune response to cocaine

Childhood adversity permanently alters the peripheral and central immune systems, increasing the sensitivity of the body's immune response to cocaine, reports a study by researchers at the IRCCS Santa Lucia Foundation and University of Rome "La Sapienza", Italy.

17 Jul 2018

Immune T cells are built to react as fast as possible, shows study

Without T cells, we could not survive. They are a key component of our immune system and have highly sensitive receptors on their surface that can detect pathogens.

17 Jul 2018

Researchers reduce size of tumors in mice by artificially activating the brain's reward system

By artificially activating the brain's reward system, researchers at the Technion-Israel Institute of Technology have dramatically reduced the size of cancerous tumors in mice. The findings were published recently in the journal Nature Communications.

16 Jul 2018

Researchers describe key role of enzyme in regulating immune response against Chagas disease parasite

In an article published recently in the journal Nature Communications, researchers affiliated with the University of São Paulo in Brazil describe the central role played by an enzyme called phosphatidylinositol 3-kinase gamma in regulating the immune response against Trypanosoma cruzi, the protozoan parasite that causes Chagas disease.

16 Jul 2018

Fruit fly research leads to potential drug for debilitating diseases caused by parasitic worms

River blindness and elephantiasis are debilitating diseases caused by parasitic worms that infect as many as 150 million people worldwide.

13 Jul 2018

Researchers create vaccine that protects against malaria in mouse models

A Yale-led team of researchers have created a vaccine that protects against malaria infection in mouse models, paving the way for the development of a human vaccine that works by targeting the specific protein that parasites use to evade the immune system.

13 Jul 2018

Study: Negative selection plays major role in cancer evolution

Natural selection shapes genomes to evolve and to adapt but, are the rules of natural selection also applying to cancer genome evolution?

13 Jul 2018

Researchers find experimental compound to treat fibrotic diseases

Normal scar tissue forms to heal an internal wound and quietly retreats when the job is done. But in many common diseases - kidney, liver and lung fibrosis -- the scar tissue goes rogue and strangles vital organs. These diseases are largely untreatable and ultimately fatal.

13 Jul 2018

Researchers decipher key component behind rising epidemic of pathogens in West Africa

A research team from several institutions being led by the University of California San Diego has deciphered a key component behind a rising epidemic of pathogens that the World Health Organization (WHO) recently added to its list of critical emerging diseases.

13 Jul 2018

Georgia State professor receives federal grant to study virus similar to Ebola virus

Dr. Christopher Basler, a professor in the Institute for Biomedical Sciences at Georgia State University, director of the university's Center for Microbial Pathogenesis and a Georgia Research Alliance Eminent Scholar in Microbial Pathogenesis, has received a two-year, $419,100 federal grant to study a virus similar to Ebola virus that causes disease in animals but not in humans.

12 Jul 2018

New clinical trial to evaluate virotherapy and immunotherapy combination for ovarian, colorectal cancers

Ludwig Cancer Research and the Cancer Research Institute announce the initiation of a clinical trial to evaluate the combination of ONCOS-102, an experimental anti-tumor virotherapy, with the checkpoint blockade antibody IMFINZI (durvalumab) for advanced ovarian and colorectal cancers.

12 Jul 2018

Study reveals link between gastrointestinal flora and acute lung injury after blood transfusions

Knowledge that the gastrointestinal flora affects both healthy physiological processes and various disease mechanisms has increased in recent years.

11 Jul 2018

Immune Response News and Research

Researchers report first randomized trial results of 'kick and kill' approach to treat HIV

UVA researchers discover how obesity may trigger harmful inflammation

New study provides important clues to developing more effective Ebola vaccines

Study finds new enzyme that lays foundations for allergic immune response

Study uncovers new protein complex that shields broken DNA ends

Mother's microbiome determines offspring's risk of developing autism

Deleting single gene in gut bacteria affects metabolism, reduces weight gain in mice

New review examines cannabinoids' potential for direct treatment of cancer

Early childhood adversity increases sensitivity of the body's immune response to cocaine

Immune T cells are built to react as fast as possible, shows study

Researchers reduce size of tumors in mice by artificially activating the brain's reward system

Researchers describe key role of enzyme in regulating immune response against Chagas disease parasite

Fruit fly research leads to potential drug for debilitating diseases caused by parasitic worms

Researchers create vaccine that protects against malaria in mouse models

Study: Negative selection plays major role in cancer evolution

Researchers find experimental compound to treat fibrotic diseases

Researchers decipher key component behind rising epidemic of pathogens in West Africa

Georgia State professor receives federal grant to study virus similar to Ebola virus

New clinical trial to evaluate virotherapy and immunotherapy combination for ovarian, colorectal cancers

Study reveals link between gastrointestinal flora and acute lung injury after blood transfusions

Exploring Strategies for Targeting Kinases in Innate Immunity eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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