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Estrogen found to promote tumor growth in breast cancers without receptors

Estrogens are known to drive tumor growth in breast cancer cells that carry its receptors, but a new study by Duke Cancer Institute researchers unexpectedly finds that estrogens play a role in fueling the growth of breast cancers without the receptors, as well as numerous other cancers.

27 Sep 2024

New study reveals growing disparities in preterm birth rates

Preterm births have increased by more than 10 percent over the past decade, with racial and socioeconomic disparities persisting over time, according to a new study analyzing more than five million births.

27 Sep 2024

UN declaration addresses antibiotic pollution and resistance

In 2007, researchers at University of Gothenburg, Sweden published the first in a series of studies showing massive pollution with antibiotics from pharmaceutical factories in India.

27 Sep 2024

Why hypoglycemia-induced glucagon secretion becomes impaired in diabetes

Findings indicate that excessive somatostatin inhibits glucagon secretion in type 1 diabetes, offering a novel target for hypoglycemia management strategies.

27 Sep 2024

A few rural towns are bucking the trend and building new hospitals

There's a new morning ritual in Pinedale, Wyoming, a town of about 2,000 nestled against the Wind River Mountains.

27 Sep 2024

12-week coffee compound study shows promising results for weight and fat reduction in at-risk individuals

Cafestol may aid in reducing body weight and visceral fat, but its impact on insulin sensitivity and glucose tolerance remains limited, according to the study.

27 Sep 2024

Epigenetic switch controls renin production in unexpected cell type

University of Virginia School of Medicine researchers have discovered how certain cells have the amazing ability to transform their function to help our bodies control our blood pressure.

26 Sep 2024

Scientists unravel the process of pore formation in cells

The formation of pores by a particular protein, gasdermin D, plays a key role in inflammatory reactions. During its activation, an inhibitory part is split off. More than 30 of the remaining protein fragments then combine to form large pores in the cell membrane, which allow the release of inflammatory messengers.

26 Sep 2024

Study uncovers hidden proteins fueling heart disease and stroke

Researchers identified key proteins linked to cardiovascular disease, highlighting new targets for drug development using genetic and observational analyses in UK and China biobanks.

26 Sep 2024

Iron deficiency common among pregnant women despite supplements

When a woman becomes pregnant, her iron requirements increase almost tenfold to support fetal development as well as her own increased iron needs.

26 Sep 2024

New drug MED6-189 shows promise against drug-resistant malaria

In 2022, nearly 619,000 global deaths due to malaria were caused by Plasmodium falciparum, the most virulent, prevalent, and deadly human malaria parasite.

26 Sep 2024

Review highlights evolving role of endovascular therapy in treating ischemic stroke

Stroke related to large vessel occlusion (LVO) is a leading cause of disability and death worldwide. Endovascular therapy (minimally invasive procedures like catheterization done inside the blood vessels) has transformed the management of these patients.

26 Sep 2024

Perceived stress can directly trigger psoriasis relapse

Innovative research has provided compelling evidence that perceived stress can directly trigger the relapse of psoriatic skin lesions. The study, presented today at the European Academy of Dermatology and Venereology (EADV) Congress 2024, is the first to scientifically validate this connection in vivo.

26 Sep 2024

Patient-derived gut organoids reveal new insights into Crohn's disease subtypes

Crohn's disease - an autoimmune disorder - is characterized by chronic inflammation of the digestive tract, resulting in a slew of debilitating gastrointestinal symptoms that vary from patient to patient.

26 Sep 2024

Global surge in childhood obesity signals an urgent health crisis

Since 1990, the rise in childhood overweight and obesity has surged across every continent, almost doubling in prevalence. While the United States has the highest prevalence, other nations are not far behind.

26 Sep 2024

Study reveals positive correlation between type 2 immunity and long-term cancer remission

Results from a preclinical study in mice, led by EPFL, and a collaborative clinical study in patients show that the type 2 immune response – associated with parasitic infection and thought to play a negative role in cancer immunity – is positively correlated with long-term cancer remission.

26 Sep 2024

Purine metabolism disruptions highlighted as crucial in Parkinson’s disease development

Parkinson's disease (PD), the second most common neurodegenerative disorder globally, has long baffled scientists with its progressive nature and debilitating effects on motor function.

26 Sep 2024

Pilot trial aims to reduce rapid weight gain and obesity risk among Latine infants

With $784,369 from the NIH, UNCG researchers will implement a pilot trial that aims to reduce rapid weight gain and obesity risk among Latine infants by supporting mothers in breastfeeding.

26 Sep 2024

Ultra-processed foods are silently altering your metabolism, scientists warn

Researchers from Germany and France uncover how ultra-processed foods impact metabolism in adolescents and young adults by analyzing urine and plasma biomarkers. Their findings suggest potential health risks linked to frequent consumption of processed foods.

26 Sep 2024

Insufficient sleep during pregnancy associated with neurodevelopmental risks in offspring

Pregnant women who do not get enough sleep may be at higher risk of having children with neurodevelopmental delays, according to new research published in the Endocrine Society's Journal of Clinical Endocrinology & Metabolism.

26 Sep 2024