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Study measures viral antigen and inflammatory biomarkers in CSF of COVID-19 patients in relation to neurologic symptoms and disease severity

Researchers investigated the impact of coronavirus disease 2019 (COVID-19) on biomarkers in the cerebrospinal fluid (CSF).

25 May 2022

Gut microbiota linked to immunocompromised people's variable response to SARS-CoV-2 vaccination

In a recent study posted to the Research Square* preprint server, researchers assessed whether disturbances in the gut microbiota weaken the serological response to the coronavirus disease 2019 (COVID-19) vaccine in inflammatory bowel disease (IBD) patients.

25 May 2022

Immunogenicity of BNT162b2 COVID-19 vaccine in melanoma patients receiving immunotherapy

In a recent study under review at the Scientific Reports journal and posted to the Research Square* preprint server, researchers evaluated the efficacy of messenger ribonucleic acid (mRNA)-based coronavirus disease 2019 (COVID-19) vaccine BNT162b2 in cancer patients under treatment with immune checkpoint inhibitors (ICIs).

25 May 2022

Biologic medications used by IBD patients boost COVID-19 vaccine response

Getting the COVID-19 vaccination strengthened one type of immune response to the SARS-CoV-2 virus in inflammatory bowel disease (IBD) patients even though they were taking immunosuppressant medication, according to investigators at Cedars-Sinai.

23 May 2022

SARS-CoV-2 mRNA vaccines do not stimulate interferon stimulatory gene expression in Aicardi Goutières Syndrome patients

A new study aimed to evaluate the immunostimulatory potential of mRNA vaccines in AGS patients.

23 May 2022

Repurposed drug clofoctol blocks SARS-CoV-2 replication in mouse study

A new paper presents the results of a mouse study using the repurposed antibacterial drug clofoctol against this virus.

23 May 2022

Olverembatinib a potent inhibitor of Omicron NTD-mediated cytokine release

Researchers determine whether mutations in the Omicron NTD influence its potential to stimulate myeloid cells and enhance inflammatory cytokine release.

22 May 2022

Evaluating serum levels of S100A9 as an inflammatory marker of unfavorable outcomes in patients with COVID-19

Investigators demonstrated S100A9 as an inflammatory biomarker among hospitalized SARS-CoV-2 patients.

20 May 2022

SARS-CoV-2 Omicron found to be more immune evasive than other variants among mild COVID-19 convalescent patients

Researchers evaluated the humoral and T lymphocyte immune responses against SARS-CoV-2 variants of concern among mild COVID-19 convalescent patients in South Australia.

19 May 2022

Study explores polyfunctionality of BNT162b2 COVID-19 vaccine-induced memory T-cells

Researchers assessed the impact of the BNT162b2 SARS-CoV-2 vaccine-induced memory T cells on the SARS-CoV-2 Omicron variant.

19 May 2022

In-depth characterization of the BA.2 versus BA.1 variant

In a recent study published in the journal Nature, researchers evaluated the pathogenicity and infectivity of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron BA.2 variant in hamsters and mice.

19 May 2022

How does diet affect COVID-19?

Scientists review the current research on how changes in diet can affect infection with SARS-CoV-2.

19 May 2022

Exosomes derived from γδ-T cells synergized with radiotherapy can control nasopharyngeal carcinoma

A research team at LKS Faculty of Medicine, The University of Hong Kong discovered that exosomes derived from γδ-T cells (γδ-T-Exos) synergised with radiotherapy can control nasopharyngeal carcinoma (NPC) by overcoming the radioresistance of NPC cancer stem cells (CSCs) and preserve their tumor-killing and T cell-promoting activities in the immunosuppressive NPC microenvironment.

18 May 2022

Scientists explore triggers associated with transplacental transmission of SARS-CoV-2

A new study examines the risk of fetal SARS-CoV-2 infection following infection of a pregnant mother with the virus.

17 May 2022

Exploring age-associated differences in T lymphocyte immune responses after BNT162b2 vaccination

Researchers compared the immunogenicity of or and reactogenicity to the BNT162b2 vaccine in Japanese adults and elders.

16 May 2022

Direct infection and replication of influenza virus in cardiomyocytes is a primary determinant of cardiac pathology associated with severe influenza

Researchers generated a recombinant influenza virus expressing micro ribonucleic acid (miRNAs) expressed in cardiomyocytes to infect mice, which served as a model to study the etiology of influenza-associated cardiac pathology.

13 May 2022

Necrosis News and Research

Study measures viral antigen and inflammatory biomarkers in CSF of COVID-19 patients in relation to neurologic symptoms and disease severity

Gut microbiota linked to immunocompromised people's variable response to SARS-CoV-2 vaccination

Immunogenicity of BNT162b2 COVID-19 vaccine in melanoma patients receiving immunotherapy

Biologic medications used by IBD patients boost COVID-19 vaccine response

SARS-CoV-2 mRNA vaccines do not stimulate interferon stimulatory gene expression in Aicardi Goutières Syndrome patients

Repurposed drug clofoctol blocks SARS-CoV-2 replication in mouse study

Olverembatinib a potent inhibitor of Omicron NTD-mediated cytokine release

Evaluating serum levels of S100A9 as an inflammatory marker of unfavorable outcomes in patients with COVID-19

SARS-CoV-2 Omicron found to be more immune evasive than other variants among mild COVID-19 convalescent patients

Study explores polyfunctionality of BNT162b2 COVID-19 vaccine-induced memory T-cells

In-depth characterization of the BA.2 versus BA.1 variant

How does diet affect COVID-19?

Exosomes derived from γδ-T cells synergized with radiotherapy can control nasopharyngeal carcinoma

Scientists explore triggers associated with transplacental transmission of SARS-CoV-2

Exploring age-associated differences in T lymphocyte immune responses after BNT162b2 vaccination

Direct infection and replication of influenza virus in cardiomyocytes is a primary determinant of cardiac pathology associated with severe influenza

Study reveals serum proteomic signatures of long COVID patients

Cost-effective ovine antibody-based therapy against SARS-CoV-2 infection

Pathogenicity and transmissibility of SARS-CoV-2-related pangolin coronavirus

Study assesses the efficacy and safety of lithium treatment in patients infected with severe SARS-CoV-2

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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