Immune Response News and Research

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The brain discovers and avoids disease much better than previously thought

The human brain is much better than previously thought at discovering and avoiding disease, a new study led by researchers at Karolinska Institutet in Sweden reports.

24 May 2017

Study findings could lead to quick and new way for predicting efficacy of cancer treatments

Once hailed as a breakthrough in cancer treatment, immunotherapies are now raising concerns as doctors note new side effects like severe allergic reactions, acute-onset diabetes and heart damage.

23 May 2017

Seattle Children’s opens first clinical trial to study IBD and GVHD in pediatric patients

In an effort to find new strategies to personalize treatment for pediatric patients, Seattle Children's has opened the first clinical trial applying next-generation T-cell receptor sequencing and single-cell gene expression analysis to better understand how the immune system drives both inflammatory bowel disease in pediatric autoimmunity patients and graft-versus host disease in pediatric bone marrow transplant patients.

From 10x Genomics, Inc. 23 May 2017

FAU researchers use robot technology to gain insights into development of malignant melanoma

Malignant melanoma is one of the most common and dangerous types of cancer. Researchers at Friedrich-Alexander Universität Erlangen-Nürnberg investigated how and why brown pigmented moles turn into malignant melanoma using innovative robot technology.

23 May 2017

UT Southwestern research shows potential of new DNA vaccine in preventing Alzheimer’s disease

A new DNA vaccine when delivered to the skin prompts an immune response that produces antibodies to protect against toxic proteins associated with Alzheimer's disease – without triggering severe brain swelling that earlier antibody treatments caused in some patients.

23 May 2017

Study identifies two T cell biomarkers that may predict survival trajectory of IPF patients

Two T cell biomarkers appear to predict the survival trajectory of patients with idiopathic pulmonary fibrosis (IPF), a lung disease that has a varied, but ultimately devastating, impact on patients, according to new research presented at the ATS 2017 International Conference.

22 May 2017

Researchers discover how the injured brain alerts immune system

Johns Hopkins researchers say they have identified a new way that cells in the brain alert the rest of the body to recruit immune cells when the brain is injured. The work was completed in mouse models that mimic infection, stroke or trauma in humans.

18 May 2017

Researchers identify antibodies that hold promise as Ebola treatments

The fight to contain the 2013-16 Ebola outbreak in West Africa was hampered by the lack of an effective treatment or vaccine. Researchers funded in part by the National Institute of Allergy and Infectious Diseases, part of the National Institutes of Health, have studied the blood of an Ebola survivor, searching for human antibodies that might effectively treat not only people infected with Ebola virus, but those infected with related viruses as well.

18 May 2017

Biochemical self-destruct trigger guards brain cells when fighting against West Nile virus

In a turnabout, a biochemical self-destruct trigger found in many other types of cells appears to guard the lives of brain cells during an infection with West Nile virus.

18 May 2017

Tumor mutation load in patient's biopsy varies by age and type of cancer

A team of investigators led by researchers at Georgetown Lombardi Comprehensive Cancer Center has found that the tumor mutation load, or TML, in a patient's cancer biopsy varied by age and the type of cancer, along with several other factors.

18 May 2017

Researchers identify many dangerous strains of TB pathogens

Researchers from the Vavilov Institute of General Genetics of the Russian Academy of Sciences (VIGG) and the Moscow Institute of Physics and Technology have established a catalog of mutations in 319 virulence genes of mycobacteria that cause tuberculosis.

16 May 2017

Scientists unravel mystery of T cell signaling process vital to immune response

The immune system cells known as T cells play a central role in the body's ability to fight infections and cancer. For decades, however, details of the molecular signaling process that leads to T cell activation have remained a mystery.

16 May 2017

Study reveals unique retinal scar in Ebola survivors

Researchers from the University of Liverpool have conducted a study of Ebola survivors to determine if the virus has any specific effects on the back on the eye using an ultra widefield retinal camera.

16 May 2017

Composition, function of intestinal bacteria could predict response to biologic drugs in IBD patients

Analysis of a patient's gut microbiome - the microbial population of the gastrointestinal tract - may be able to predict the likelihood of successful treatment for inflammatory bowel disease with biologic drugs that target immune system activity.

16 May 2017

IBM scientists identify new way to trigger the body's immune response to fight diseases

IBM announced its researchers have identified a new way to trigger the body's immune response by using polymer-coated graphene sheets. The research was recently published in Nature Communications.

16 May 2017

Research findings provide insight into mechanisms underlying differences in efficacy of anti-TNF drugs

Osaka University-led researchers identified differences in how three drugs bind to tumor necrosis factor, a key mediator of inflammatory disease. The team used sedimentation velocity analytical ultracentrifugation to investigate drug-target binding in a physiological environment and at clinically-relevant concentrations.

15 May 2017

Study findings could pave way for better drugs to fight against parasitic infections

Immune cells, called macrophages, may rely on a compound to signal an attack to beat back attacks from parasitic worms, according to an international team of researchers, including Zissis C. Chroneos, associate professor of pediatrics, and microbiology and immunology at Penn State College of Medicine.

12 May 2017

Phase 1 clinical studies reveal safety, tolerability of therapeutic vaccine in celiac disease patients

ImmusanT, Inc., a clinical-stage company developing Nexvax2, a therapeutic vaccine intended to protect against the effects of gluten exposure while maintaining a gluten-free diet in HLA-DQ2.5+ patients with celiac disease, today announced the publication of positive data from two Phase 1 clinical trials of Nexvax2 in celiac disease.

12 May 2017

Discovery of key signals in the lungs and liver could pave way for immune disorder treatments

The discovery of key signals that help tissues repair after injury could pave the way for new treatments for asthma and organ scarring, a study suggests.

12 May 2017

Scientists reveal how immune cells activate to kill parasitic worms

An international team of researchers including Zissis C. Chroneos, associate professor of pediatrics, and microbiology and immunology at Penn State College of Medicine, reveals how immune cells called macrophages activate to kill parasitic worms.

11 May 2017

Immune Response News and Research

The brain discovers and avoids disease much better than previously thought

Study findings could lead to quick and new way for predicting efficacy of cancer treatments

Seattle Children’s opens first clinical trial to study IBD and GVHD in pediatric patients

FAU researchers use robot technology to gain insights into development of malignant melanoma

UT Southwestern research shows potential of new DNA vaccine in preventing Alzheimer’s disease

Study identifies two T cell biomarkers that may predict survival trajectory of IPF patients

Researchers discover how the injured brain alerts immune system

Researchers identify antibodies that hold promise as Ebola treatments

Biochemical self-destruct trigger guards brain cells when fighting against West Nile virus

Tumor mutation load in patient's biopsy varies by age and type of cancer

Researchers identify many dangerous strains of TB pathogens

Scientists unravel mystery of T cell signaling process vital to immune response

Study reveals unique retinal scar in Ebola survivors

Composition, function of intestinal bacteria could predict response to biologic drugs in IBD patients

IBM scientists identify new way to trigger the body's immune response to fight diseases

Research findings provide insight into mechanisms underlying differences in efficacy of anti-TNF drugs

Study findings could pave way for better drugs to fight against parasitic infections

Phase 1 clinical studies reveal safety, tolerability of therapeutic vaccine in celiac disease patients

Discovery of key signals in the lungs and liver could pave way for immune disorder treatments

Scientists reveal how immune cells activate to kill parasitic worms

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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