Necrosis News and Research

RSS

Researchers visualize molecular organization of TNFα receptor molecules

Whether a sick cell dies, divides, or travels through the body is regulated by a sophisticat-ed interplay of signal molecules and receptors on the cell membrane.

17 Jan 2020

Loss of stress hormone is a hallmark of pancreatitis, shows study

In work that could have clinical implications, UT Southwestern researchers find that humans and mice with pancreatitis are deficient in a stress hormone called FGF21.

9 Jan 2020

Updated guideline for management of osteoarthritis of the hand, hip and knee released

Today, the American College of Rheumatology, in partnership with the Arthritis Foundation, released the 2019 ACR/AF Guideline for the Management of Osteoarthritis of the Hand, Hip and Knee.

7 Jan 2020

Study finds new drivers of destructive inflammation

Scientists describe in Nature Immunology an entirely new molecular process in mice that triggers T cell-driven inflammation and causes different auto-immune diseases.

17 Dec 2019

New tool gives more reliable and precise results in cancer research

Every cell contains a vast number of proteins, each of which has a specific function, for example as a receptor for another molecule or an enzyme that catalyzes chemical reactions.

16 Dec 2019

Award to help advance development of diagnostic test for necrotizing enterocolitis

The Eunice Kennedy Shriver National Institute of Child Health and Human Development of the National Institutes of Health has awarded Chosen Diagnostics Inc, a spin-out company, a $299,641 Phase I Small Business Technology Transfer award.

9 Dec 2019

New technology gives Aussies more prawns to enjoy for Christmas

Australians will be enjoying more Aussie-grown prawns this Christmas thanks to a new prawn health check developed by Australia’s national science agency, CSIRO.

6 Dec 2019

Researchers design new antitumoral drug release strategy for breast cancer treatment

The local release of antitumoral drugs through bacterial proteins in the treatment of breast cancer can mark a before and after in precision medicine.

21 Nov 2019

Subpopulations of tumor cells may exhibit diverging behaviors from bulk tumor

Subpopulations of tumor cells may exhibit diverging behaviors from the bulk tumor due to an alternate stress response that diverts tumor cells from apoptotic death.

20 Nov 2019

Researchers discover new pathway to 'reprogram' killer cells

Killer cells of the immune system detect and kill infected cells or cancer cells. Researchers at the Institute of Pathology at the University of Bern have now discovered that the mechanism by which certain immune cells kill their target cells can also be used to control the killer cells themselves.

19 Nov 2019

Study finds vitamin B12 deficiency in pregnancy may induce obesity

A new study which was presented at the annual conference of Society for Endocrinology reports that vitamin B12 deficiency could disrupt the normal metabolism of fat and could indirectly contribute to weight gain and obesity in pregnancy. This emphasizes the need supplement this vitamin during pregnancy, because obesity in pregnancy is linked to a number of adverse health outcomes over the long term, including diabetes.

12 Nov 2019

Juvenile immune arthritis – new treatments wanted

Juvenile immune arthritis (JIA) is a severely undertreated condition, and new medications are badly needed to relieve the signs and symptoms of the illness, according to a new study presented at the 2019 ACR/ARP Annual Meeting.

11 Nov 2019

Acute kidney injury on the rise in hospitalized pregnant women

A study presented at ASN Kidney Week 2019 (November 5 to November 10) shows that the rate of acute kidney injury (AKI) is rising among US women who are hospitalized in pregnancy. The highest risk is in pregnant diabetic women. Women who suffer acute damage to the kidney while pregnant have 260 times the risk of death while in hospital compared to other pregnant women, at 2.6% vs 0.01%. Both mother and baby are at risk of increased illness and death if the woman has kidney injury during pregnancy.

11 Nov 2019

Tocilizumab more effective than rituximab in achieving low disease activity in RA patients

New research discovered that tocilizumab is more effective than rituximab in achieving low disease activity in patients with rheumatoid arthritis whose synovial tissue show a low level of B cell infiltration and did not respond to conventional synthetic disease-modifying anti-rheumatic drugs (conventional synthetic DMARDs) or tumor necrosis factor inhibitors first.

11 Nov 2019

Study provides first data on infectious risk in children exposed to non-TNFi biologics and tofacitinib

A new study found that very few serious infections were seen in children born to mothers with chronic inflammatory diseases who used non-TNFi biologics or tofacitinib during pregnancy compared to children not exposed to these drugs and children exposed to TNFi biologics in utero.

10 Nov 2019

Study reveals safety, efficacy of live zoster vaccine for people taking TNF inhibitors

According to new research findings presented this week at the 2019 ACR/ARP Annual Meeting, the live zoster virus vaccine is safe for people who are currently receiving tumor necrosis factor inhibitor (TNFi) biologic therapies for various indications.

10 Nov 2019

Study finds reliable biomarker for noninvasive detection of deadly infant disease

A diagnostic study of 136 premature infants found that a protein involved in managing harmful bacteria in the human intestine is a reliable biomarker for the noninvasive detection of necrotizing enterocolitis.

8 Nov 2019

Vitamin D and omega-3 fatty acids are not effective at reducing systemic inflammation

Vitamin D and marine omega-3 fatty acids -- also known as fish oil -- are purported to have many health benefits, including reducing systemic inflammation.

7 Nov 2019

UK aims to lead with cutting-edge radiation therapy

The UK is all set to launch its run into the future as the undisputed leader in the field of personalized and effective radiation therapy. The proposal is undergirded by a whopping £56 million, which will be used to set up and fund advanced radiation therapy research by a new collaborative setup, Cancer Research UK RadNet, over five years. This is the largest sum ever invested by this organization into radiotherapy research.

4 Nov 2019

Study: MIB2 improves inflammation by degrading CYLD enzyme

The tumor suppressor CYLD lysine 63 deubiquitinase (CYLD) is a deubiquitinating enzyme that suppresses polyubiquitin-dependent signaling pathways, including the proinflammatory and cell growth-promoting NF-κB pathway.

30 Oct 2019

Necrosis News and Research

Researchers visualize molecular organization of TNFα receptor molecules

Loss of stress hormone is a hallmark of pancreatitis, shows study

Updated guideline for management of osteoarthritis of the hand, hip and knee released

Study finds new drivers of destructive inflammation

New tool gives more reliable and precise results in cancer research

Award to help advance development of diagnostic test for necrotizing enterocolitis

New technology gives Aussies more prawns to enjoy for Christmas

Researchers design new antitumoral drug release strategy for breast cancer treatment

Subpopulations of tumor cells may exhibit diverging behaviors from bulk tumor

Researchers discover new pathway to 'reprogram' killer cells

Study finds vitamin B12 deficiency in pregnancy may induce obesity

Juvenile immune arthritis – new treatments wanted

Acute kidney injury on the rise in hospitalized pregnant women

Tocilizumab more effective than rituximab in achieving low disease activity in RA patients

Study provides first data on infectious risk in children exposed to non-TNFi biologics and tofacitinib

Study reveals safety, efficacy of live zoster vaccine for people taking TNF inhibitors

Study finds reliable biomarker for noninvasive detection of deadly infant disease

Vitamin D and omega-3 fatty acids are not effective at reducing systemic inflammation

UK aims to lead with cutting-edge radiation therapy

Study: MIB2 improves inflammation by degrading CYLD enzyme

Discover how SciY empowers scientists

Why use light scattering to analyze proteins and viral vectors?

Changing the landscape of R&D to build clinical success from the ground up

Latest News