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NVX-CoV2373 vaccine found to induce functional SARS-CoV-2-specific T cell responses

In a recent study researchers evaluated the T cell responses elicited by full-length severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike (S) protein vaccine NVX-CoV2373.

12 Apr 2022

Nanocell COVID-19 vaccine elicits potent neutralizing response

A new study describes the high level of neutralizing antibodies elicited by a nanocell vaccine against SARS-CoV-2 in vitro, in vivo, and human studies.

11 Apr 2022

Chromatin accessibility as an early marker of severe COVID-19

A new study explores the possible use of chromatin remodeling in predicting a severe clinical trajectory for COVID-19.

11 Apr 2022

Challenges, unmet needs and future opportunities in COVID-19 therapeutics

In a recent article published in the journal Proceedings of the National Academy of Sciences (PNAS), researchers reviewed the present-day therapeutic landscape of coronavirus disease 2019 (COVID-19) and addressed future opportunities to overcome challenges that hinder drug development and improve the global preparedness for future pandemics.

10 Apr 2022

Shared gene expression signatures in type 1 diabetics treated with IL-2 and COVID-19 patients

Researchers assess the impact of interval administration of LD-IL-2 was examined in 18 T1D patients who received a three-day dosing interval.

10 Apr 2022

Novel therapy advances to clinical trial for the treatment of glioblastoma

A novel therapy studied at the Medical College of Wisconsin (MCW) Cancer Center has led to a clinical trial for the treatment of glioblastoma, a rare and aggressive form of brain cancer, yet the most common primary brain tumor in adults.

10 Apr 2022

Substantial SARS-CoV-2 infection in perivascular cells of inflamed blood vessels

A new study demonstrated that vascular inflammation leads to heightened SARS-CoV-2 infection in perivascular cells.

8 Apr 2022

Study investigates biochemical, biophysical, and immunological profile of COVID-19 respiratory secretions

A new study assessed the biophysical, immunological, and biochemical characteristics of respiratory secretions in acute SARS-CoV-2 infections.

7 Apr 2022

Transcriptional reprogramming of monocytes in COVID-19

In a recent study posted to the bioRxiv* server, researchers examined the functionality of cluster of differentiation 14-positive (CD14+) monocytes in patients with mild or moderate coronavirus disease 2019 (COVID-19).

7 Apr 2022

Researchers discover over 40 new genetic markers for Alzheimer’s disease

A new Nature Genetics study describes over 70 gene markers that appear to be significantly associated with AD risk using translational genomics.

6 Apr 2022

Phenotypic changes in monocytes from COVID-19 patients

Researchers investigate monocytes to better understand how infection with SARS-CoV-2 can cause dysfunction in these immune cells.

5 Apr 2022

Study generates a picture of the myocardial transcriptional landscape of COVID-19

Researchers profiled cardiac tissue transcriptomes of COVID-19 patients.

5 Apr 2022

Higher cereal fiber intake associated with lower inflammation

A new study assesses the association between dietary fiber intake with inflammatory markers associated with cardiovascular disease.

4 Apr 2022

Study explores molecular mechanisms underlying SARS-CoV-2 infection of macrophages and the induction of pro-inflammatory cytokines

Researchers examined the role of sialic acid-binding immunoglobulin-type lectins-1, a myeloid cell-specific receptor, in facilitating SARS-CoV-2 infection of ACE2-deficient macrophages and its effect on pro-inflammatory cytokine expression.

1 Apr 2022

Necrosis News and Research

NVX-CoV2373 vaccine found to induce functional SARS-CoV-2-specific T cell responses

Nanocell COVID-19 vaccine elicits potent neutralizing response

Chromatin accessibility as an early marker of severe COVID-19

Challenges, unmet needs and future opportunities in COVID-19 therapeutics

Shared gene expression signatures in type 1 diabetics treated with IL-2 and COVID-19 patients

Novel therapy advances to clinical trial for the treatment of glioblastoma

Substantial SARS-CoV-2 infection in perivascular cells of inflamed blood vessels

Study investigates biochemical, biophysical, and immunological profile of COVID-19 respiratory secretions

Transcriptional reprogramming of monocytes in COVID-19

Researchers discover over 40 new genetic markers for Alzheimer’s disease

Phenotypic changes in monocytes from COVID-19 patients

Study generates a picture of the myocardial transcriptional landscape of COVID-19

Higher cereal fiber intake associated with lower inflammation

Study explores molecular mechanisms underlying SARS-CoV-2 infection of macrophages and the induction of pro-inflammatory cytokines

Liposomes tailored for pulmonary delivery for treating acute respiratory distress syndrome

Messenger ribonucleic acid boosters shown to be effective against Omicron infections in mice

Role of SARS-CoV-2 S1 subunit in severe COVID-19

Durability and functionality of the humoral and T-cell response to SARS-CoV-2 and its variants in recovered patients

Tuberculosis infection protects mice against COVID-19

Study explores macrophage susceptibility to SARS-CoV-2 virions

Industry Focus eBook - Forensics & toxicology (2nd edition) eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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