CLARITY News and Research

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The lipid-exchanged, anatomically rigid, imaging/immunostaining compatible, tissue hydrogel (CLARITY) method was initially designed in 2013 by Chung and Deisseroth at the Stanford University School of Medicine. Using this process, post-mortem organs can be labeled for proteins and nucleic acids, enabling analysis of intact samples to create detailed 3D images.

What does recovery from COVID-19 look like? It depends. A pulmonologist explains.

Reports of recovery from serious illness caused by the coronavirus have been trickling in from around the world.

9 Apr 2020

Metrion Biosciences and International Scientific Consortium publish data and new recommendations for in vitro risk assessment of the cardiac safety of new medicines

Metrion today announced it has contributed to two new peer-reviewed papers under the U.S. FDA CiPA (Comprehensive in vitro Proarrhythmia Assay) initiative.

From Metrion Biosciences Limited 7 Apr 2020

California lawmakers struggle to conduct business amid COVID-19 lockdown

The weekend before California shuttered its Capitol building, Senate leader Toni Atkins spent hours on the phone - taking the roles of a student learning from epidemiologists and a legislator discussing with colleagues how the country's most populous state should respond to the COVID-19 crisis.

25 Mar 2020

Cryo-electron microscopy helps visualize ball-and-chain inactivation of ion channels

Ion channels, which allow potassium and sodium ions to flow in and out of cells, are crucial in neuronal 'firing' in the central nervous system and for brain and heart function.

19 Mar 2020

New understanding of signaling molecule interleukin-2 can guide drug discovery efforts

The signaling molecule interleukin-2 (IL-2) has long been known to have powerful effects on the immune system, but efforts to harness it for therapeutic purposes have been hampered by serious side effects.

17 Mar 2020

Former federal virus hunter says U.S. needs to act before new germs ‘kick your door in’

When the federal government decided to investigate the threat viruses in animals posed to humans, Dennis Carroll helped lead the charge.

16 Mar 2020

A miRNA signature linked to local-regional failure and overall survival after pancreatic cancer resection

The cover for issue 10 of Oncotarget features Figure 3, "Overall survival (OS) for high (red) versus low (black) risk groups in the (A) OSU, (B) TCGA, and (C) SNU resected cohorts," by Wolfe, et al.

13 Mar 2020

Preserving kidney function in patients with diabetic kidney disease

Diabetic kidney disease, which affects between 20 to 40 percent of people with diabetes, is a serious complication that can ultimately lead to end-stage kidney disease--a life-threatening condition that requires either dialysis or kidney transplant.

13 Mar 2020

Microbial DNA in the blood could help identify who has cancer

When Gregory Poore was a freshman in college, his otherwise healthy grandmother was shocked to learn that she had late-stage pancreatic cancer. The condition was diagnosed in late December. She died in January.

11 Mar 2020

FAIR Health launches website feature to aid shared decision making for palliative care

Today FAIR Health launched a groundbreaking website feature that combines clinical and cost information to support seriously and chronically ill patients and their caregivers in the process of shared decision making with clinicians for three palliative care scenarios.

10 Mar 2020

Pence leaves out key details about health coverage of coronavirus testing

Amid ongoing concern about the new coronavirus, Vice President Mike Pence sought to assure Americans that their health insurance will cover the tests needed for diagnosis.

6 Mar 2020

Public health experts call for coordinated communication and outreach on COVID-19

On Thursday in the National Academy of Medicine's Perspectives, public health leaders including CUNY Graduate School of Public Health and Health Policy Distinguished Lecturer Scott Ratzan, MD called for informed and active public policy leadership to employ strategically coordinated health communication and outreach on COVID-19 and other emerging global health threats.

5 Mar 2020

During a pandemic, states’ patchwork of crisis plans could mean uneven care

A possible coronavirus pandemic could overwhelm the nation's hospitals and force doctors into difficult decisions about how to allocate limited resources. Yet, experts say, only a handful of states have done the work necessary to prepare for such worst-case scenarios.

5 Mar 2020

Readers and tweeters dive into debate over ‘Medicare for All’

Your criticism about former Vice President Joe Biden’s "Medicare for All" cost estimates is spot-on but leaves out important savings.

28 Feb 2020

SEER: A better tool to image disease

Scientists from the University of South California (USC) report the development of a novel technique to image living cells in greater detail and increased clarity. The study, published in the journal Nature Communications, describes a technology which can confer the ability to actually see things going wrong – a great advantage in the study of health and disease.

5 Feb 2020

Good rehab is hard to find

Pattie Vargas saw with frightening clarity that her son Joel, 25 at the time, had a life-threatening drug problem. He came home one day in 2007 "high as a kite," went to bed and slept four days straight, Vargas, now a 65-year-old resident of Vacaville, California, recalls.

5 Feb 2020

Expert genomics panel disputes certain genes linked to a dangerous heart condition

A panel of experts have said that nine genes linked to a dangerous heart disorder called long QT syndrome, are not associated with the condition.

27 Jan 2020

ClinGen expert panel disputes nine genes linked to long QT syndrome

Geneticists and heart specialists around the world had previously reported 17 genes to cause long QT syndrome, a little-known inherited heart condition. However, the Clinical Genome Resource's expert panel has critically reevaluated the scientific evidence for all 17 reported genes, disputing nine of the genes and revealing only three of the genes to be definitively associated with the most common form of the disease.

27 Jan 2020

People with acquired paralysis later in life report higher rates of depression, anxiety

People with facial paralysis are more likely to face depression and anxiety than the general population, especially if the paralysis occurs later in life rather than at birth, according to a recent study from Oregon State University.

23 Jan 2020

Experts highlight safety and role of low/no calorie sweeteners in helping reduce sugar intake

The International Sweeteners Association welcomes the publication this month of a new scientific report by Ashwell et al. in Nutrition Research Reviews.

23 Jan 2020

CLARITY News and Research

Further Reading

What does recovery from COVID-19 look like? It depends. A pulmonologist explains.

Metrion Biosciences and International Scientific Consortium publish data and new recommendations for in vitro risk assessment of the cardiac safety of new medicines

California lawmakers struggle to conduct business amid COVID-19 lockdown

Cryo-electron microscopy helps visualize ball-and-chain inactivation of ion channels

New understanding of signaling molecule interleukin-2 can guide drug discovery efforts

Former federal virus hunter says U.S. needs to act before new germs ‘kick your door in’

A miRNA signature linked to local-regional failure and overall survival after pancreatic cancer resection

Preserving kidney function in patients with diabetic kidney disease

Microbial DNA in the blood could help identify who has cancer

FAIR Health launches website feature to aid shared decision making for palliative care

Pence leaves out key details about health coverage of coronavirus testing

Public health experts call for coordinated communication and outreach on COVID-19

During a pandemic, states’ patchwork of crisis plans could mean uneven care

Readers and tweeters dive into debate over ‘Medicare for All’

SEER: A better tool to image disease

Good rehab is hard to find

Expert genomics panel disputes certain genes linked to a dangerous heart condition

ClinGen expert panel disputes nine genes linked to long QT syndrome

People with acquired paralysis later in life report higher rates of depression, anxiety

Experts highlight safety and role of low/no calorie sweeteners in helping reduce sugar intake

Industry Focus eBook - Neurology/Neuroscience - 2nd edition eBook

Latest eBooks

New horizons in drug discovery: High-throughput & target-to-therapy advances

A practical guide to lipid nanoparticle formulation and resizing

Editorial Focus eBook - Spatial and single-cell omics (1st edition)

Industry Focus eBook - Analytical Chemistry (3rd edition)

How Omics Technologies Are Transforming Biological Research and Drug Discovery

How microplastics and bacteria interact to drive antibiotic resistance

Single-cell proteomics: Revealing proteome diversity from cellular heterogeneity to non-canonical biology