Immune Response News and Research

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Personalized DXM-loaded leukosomes may help treat inflammation

Nanosized Trojan horses created from a patient's own immune cells have successfully treated inflammation by overcoming the body's complex defense mechanisms, perhaps leading to broader applications for treating diseases characterized by inflammation, such as cancer and cardiovascular diseases.

24 May 2016

Heart failure patients who receive influenza vaccine less likely to develop dementia

Influenza vaccination is associated with a lower risk of dementia in patients with heart failure, according to a study in more than 20 000 patients presented today at Heart Failure 2016 and the 3rd World Congress on Acute Heart Failure by Dr Ju-Chi Liu, director of the Division of Cardiovascular Medicine, Department of Medicine, Taipei Medical University - Shuang Ho Hospital, in New Taipei City, Taiwan.

24 May 2016

Flu jab linked to reduced hospitalisation risk in heart failure patients

The flu jab is associated with a reduced risk of hospitalisation in patients with heart failure, according to research presented today in a late breaking trial session at Heart Failure 2016 and the 3rd World Congress on Acute Heart Failure.

24 May 2016

Ongoing treatment with nivolumab shows benefit in advanced kidney cancer patients

Only 12% of kidney cancer patients with advanced disease survive five years after their initial treatment. In a Roswell Park Cancer Institute-led study, scientists report that some patients with advanced kidney cancer who continued to receive a novel immunotherapy drug after their disease progressed saw clinical benefit.

24 May 2016

Researchers identify trigger for immune cells' inflammatory response

Scientists at the University of Bristol have identified the trigger for immune cells' inflammatory response - a discovery that may pave the way for new treatments for many human diseases.

23 May 2016

New collaborative research center to investigate promising aspects of mucosal immunology

Immunology - and the idea that many diseases can best be addressed by boosting the body's own immune response - is one of the hottest areas in medical research and clinical treatment.

22 May 2016

Wresting back control of CHI3L1 protein could stave off cancer spread in mice

For cancer to spread, the cells that take off into the bloodstream must find a tissue that will permit them to thrive. They don't just go looking, though. Instead, they actively prepare the tissue, in one case by co-opting a protein that suppresses defenses the body would otherwise mount.

21 May 2016

NS5 viral protein could be promising vaccine target against Zika virus

A viral protein known as NS5 is a promising target for vaccines against Zika and related viruses, according to National Institutes of Health scientists and colleagues at Mount Sinai's Icahn School of Medicine.

20 May 2016

Borrowed immune system may help combat cancer

A new step in cancer immunotherapy: researchers from the University of Oslo/Oslo University Hospital and the Netherlands Cancer Institute show that even if one's own immune cells cannot recognize and fight their tumors, someone else's immune cells might.

20 May 2016

New skin test for TB infection proves safe, effective in clinical trials

A new skin test for tuberculosis infection has proven safe, easy to administer and accurate in two Phase III clinical trials, according to research presented at the ATS 2016 International Conference.

19 May 2016

Study shows expression of high-affinity TCRs linked with spontaneous control of HIV infection

A small number of patients infected by HIV spontaneously control viral replication without antiretroviral therapy, and do not develop the disease. The ability of these rare patients, known as "HIV controllers", to suppress HIV replication appears to be down to a highly effective immune response.

19 May 2016

Landmark study characterizes evolution of symptoms, signs of acute HIV infection

Acute HIV infection (AHI) contributes significantly to HIV transmission and may be important for intervention strategies seeking to reduce incidence and achieve a functional cure.

19 May 2016

Crtc switch activated during fasting helps halt spread of intestinal bacteria into bloodstream

A molecular pathway that is activated in the brain during fasting helps halt the spread of intestinal bacteria into the bloodstream, according to a new study by a team of researchers at the Salk Institute.

18 May 2016

Food components can have significant influence on immune system

An international team of researchers under the leadership of the LIMES Institute and the excellence cluster ImmunoSensation of the University of Bonn unraveled a new regulatory mechanism how food components and environmental factors influence the immune system.

18 May 2016

Could worm infection counter IBD? An interview with Dr Loke and Dr Cadwell

The hygiene hypothesis refers to the idea that decreased exposure to certain infectious agents (because of better hygiene) is the reason why we have seen an increase in inflammatory diseases in the developed world.

17 May 2016

Researchers reveal new mechanism that helps breast cancer cells engage MDSCs

Not every breast cancer tumor follows the same path to grow. Some tumors have the assistance of myeloid-derived suppressor cells (MDSCs), a diverse type of immune cell involved in the suppression of the body's response against tumors.

17 May 2016

Potential vaccine that resembles sugar structures may help fight against gut bacterium C. difficile

A vaccine against one of the most dangerous hospital germs may soon be available. Scientists from the Max Planck Institute of Colloids and Interfaces in Potsdam and the Freie Universität Berlin have developed a substance that elicits an immune response against the gut bacterium Clostridium difficile.

13 May 2016

Mouse models of Zika virus infection in pregnancy provide basis to develop vaccines, treatments

Two mouse models of Zika virus infection in pregnancy have been developed by a team of researchers at Washington University School of Medicine in St. Louis. In them, the virus migrated from the pregnant mouse's bloodstream into the placenta, where it multiplied, then spread into the fetal circulation and infected the brains of the developing pups.

12 May 2016

Simultaneous DNA, RNA and protein analysis to enhance cancer immunology studies: an interview with Dr Joseph Beechem

Cancer immunology is all about how your immune cells are going to fight and kill your tumor cells. If you look at the pure genetic code of a T-cell that's going to kill your tumor compared to the same cell that has been “put-to-sleep” (by the tumor), the pure genetic DNA content of those two cells are identical.

From NanoString Technologies 11 May 2016

lncRNA in placenta may help protect unborn baby from invading pathogens

The human placenta is an organ unlike any other. During the course of nine months it is formed by the embryo, sustains life and then is shed.

10 May 2016

Immune Response News and Research

Personalized DXM-loaded leukosomes may help treat inflammation

Heart failure patients who receive influenza vaccine less likely to develop dementia

Flu jab linked to reduced hospitalisation risk in heart failure patients

Ongoing treatment with nivolumab shows benefit in advanced kidney cancer patients

Researchers identify trigger for immune cells' inflammatory response

New collaborative research center to investigate promising aspects of mucosal immunology

Wresting back control of CHI3L1 protein could stave off cancer spread in mice

NS5 viral protein could be promising vaccine target against Zika virus

Borrowed immune system may help combat cancer

New skin test for TB infection proves safe, effective in clinical trials

Study shows expression of high-affinity TCRs linked with spontaneous control of HIV infection

Landmark study characterizes evolution of symptoms, signs of acute HIV infection

Crtc switch activated during fasting helps halt spread of intestinal bacteria into bloodstream

Food components can have significant influence on immune system

Could worm infection counter IBD? An interview with Dr Loke and Dr Cadwell

Researchers reveal new mechanism that helps breast cancer cells engage MDSCs

Potential vaccine that resembles sugar structures may help fight against gut bacterium C. difficile

Mouse models of Zika virus infection in pregnancy provide basis to develop vaccines, treatments

Simultaneous DNA, RNA and protein analysis to enhance cancer immunology studies: an interview with Dr Joseph Beechem

lncRNA in placenta may help protect unborn baby from invading pathogens

Understanding the DNA Damage Response in Innate Immunity eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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