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Altered amino acid metabolism could contribute to diabetes-associated peripheral neuropathy

Approximately half of people with type 1 or type 2 diabetes experience peripheral neuropathy - weakness, numbness, and pain, primarily in the hands and feet.

25 Jan 2023

Genetically increasing omega-3 fatty acid production improves glucose balance in obese mice

A new study from researchers at Laval University in Quebec, Canada, shows that genetically increasing omega-3 fatty acid production, without direct gut microbiota contact, improves the balance of insulin and glucagon (glucose balance) in obese mice.

25 Jan 2023

Injectable hydrogel composite loaded with stem cells shows success in treating perianal fistulas

In a new study using a rat model of Crohn's disease, a biodegradable hydrogel composite loaded with stem cells, developed by Johns Hopkins Medicine researchers, in a collaborative effort with the Whiting School of Engineering, has shown significant success in treating perianal fistulas (PAF) — one of the many complications of Crohn's disease.

25 Jan 2023

Rural-dwelling Americans at higher risk of developing heart failure compared to their urban counterparts

Adults living in rural areas of the United States have a 19% higher risk of developing heart failure compared to their urban counterparts, and Black men living in rural areas have an especially higher risk - 34%, according to a large observational study supported by the National Institutes of Health.

25 Jan 2023

Ospemifene and systemic hormone therapy improve vulvovaginal atrophy symptoms, study suggests

As women age, they are more susceptible to vaginal dryness and pain during intercourse because of vulvovaginal atrophy (VVA).

25 Jan 2023

Study finds link between self-stigma and glycated hemoglobin in people with type 1 diabetes

Individuals with chronic medical conditions may experience self-stigma, or negative beliefs, emotional reactions, and behaviors towards themselves as a result of their illness.

25 Jan 2023

E-cigarette aerosols can cause cellular and molecular changes in the lungs

New research published in The FASEB Journal indicates that e-cigarettes can cause cellular and molecular changes in the lungs.

25 Jan 2023

The efficacy of clarithromycin versus levofoxacin-based regimens for H.pylori treatment in naïve patients after the COVID-19 pandemic misuse of antibiotics

Researchers explored the eradication rates of Helicobacter pylori utilizing levofloxacin and clarithromycin-based regimens in patients with prior COVID-19 therapy.

25 Jan 2023

Targeting newly discovered signaling pathway could boost the potency of cancer therapeutics

Cells zealously protect the integrity of their genomes, because damage can lead to cancer or cell death. The genome - a cell's complete set of DNA - is most vulnerable while it is being duplicated before a cell divides. Cancer cells constantly are dividing, so their genomes are constantly in jeopardy.

24 Jan 2023

Unfavorable healthcare experiences may increase the likelihood of caregivers to self-medicate

Caregivers need care, too. And now, researchers from Japan have found that their experience with healthcare professionals while caring for someone else affects their own healthcare choices.

24 Jan 2023

Neurons in a bow-shaped brain region become hyperactive after chronic stress exposure

It's clear that chronic stress can impact our behavior, leading to problems like depression, reduced interest in things that previously brought us pleasure, even PTSD.

24 Jan 2023

Study finds link between physical activity levels and susceptibility to upper respiratory tract infections in children

Higher levels of daily physical activity are associated with reduced susceptibility to upper respiratory tract infections such as the common cold, suggests a study of 104 Polish children published in Pediatric Research.

24 Jan 2023

Researchers compare high- and low-dose exercise therapy in patients with knee osteoarthritis

Researchers from Karolinska Institutet have compared high dose exercise therapy versus low dose in patients with symptomatic knee osteoarthritis.

24 Jan 2023

Researchers review the association between endogenous retrovirus reactivation and aging

Researchers explored the role of endogenous retrovirus (ERV) reactivation in the aging process.

24 Jan 2023

Researchers uncover new mechanism that plays key role in the progression of alcohol-related liver disease

Alcohol-related liver disease is among the most common causes of morbidity and mortality worldwide. Due to an incomplete understanding of the factors contributing to disease development, liver transplantation is still the only available cure.

24 Jan 2023

Exercising with others offers greater benefits to older people

Exercise is beneficial in obvious ways like getting a leaner and stronger body, yet its benefits can also improve the brain, including in older adults.

24 Jan 2023

Study shows the effectiveness of web-based interventions for promoting weight loss

Being obese and overweight can cause serious chronic diseases, which include type 2 diabetes mellitus, cardiovascular disease, hypertension, sleep apnea, osteoarthritis, and certain types of cancer.

24 Jan 2023

Modulating the lipid composition to treat bronchial asthma

Bronchial asthma, a chronic inflammatory disease of the airways that is reversible in certain cases, usually presents with cough, difficulty of breathing, and wheezing.

24 Jan 2023

Care management processes for people with chronic conditions increased from 2019 to 2021

Although primary care clinics were disrupted by the COVID-19 pandemic, a study by Minnesota researchers showed that care management processes for chronic disease care in the primary care setting generally increased from 2019 to 2021.

23 Jan 2023

Mitochondrial dysfunction and endothelial impairment linked to many cardiovascular diseases

Many cardiovascular diseases, such as atherosclerosis, or 'hardening of the arteries,' correlate to mitochondrial dysfunction and endothelial impairment in the tissues of the heart and blood vessels.

23 Jan 2023

Chronic News and Research

Altered amino acid metabolism could contribute to diabetes-associated peripheral neuropathy

Genetically increasing omega-3 fatty acid production improves glucose balance in obese mice

Injectable hydrogel composite loaded with stem cells shows success in treating perianal fistulas

Rural-dwelling Americans at higher risk of developing heart failure compared to their urban counterparts

Ospemifene and systemic hormone therapy improve vulvovaginal atrophy symptoms, study suggests

Study finds link between self-stigma and glycated hemoglobin in people with type 1 diabetes

E-cigarette aerosols can cause cellular and molecular changes in the lungs

The efficacy of clarithromycin versus levofoxacin-based regimens for H.pylori treatment in naïve patients after the COVID-19 pandemic misuse of antibiotics

Targeting newly discovered signaling pathway could boost the potency of cancer therapeutics

Unfavorable healthcare experiences may increase the likelihood of caregivers to self-medicate

Neurons in a bow-shaped brain region become hyperactive after chronic stress exposure

Study finds link between physical activity levels and susceptibility to upper respiratory tract infections in children

Researchers compare high- and low-dose exercise therapy in patients with knee osteoarthritis

Researchers review the association between endogenous retrovirus reactivation and aging

Researchers uncover new mechanism that plays key role in the progression of alcohol-related liver disease

Exercising with others offers greater benefits to older people

Study shows the effectiveness of web-based interventions for promoting weight loss

Modulating the lipid composition to treat bronchial asthma

Care management processes for people with chronic conditions increased from 2019 to 2021

Mitochondrial dysfunction and endothelial impairment linked to many cardiovascular diseases

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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