in vitro News and Research

RSS

Valsartan might help prevent Alzheimer's disease

Alzheimer disease (AD), a neurodegenerative disease that is the most common form of dementia, is characterized by the formation in the brain of plaques containing misfolded beta-amyloid protein.

25 Oct 2007

New target for Hepatocellular carcinoma therapy

Hepatocellular carcinoma (HCC) is a major health problem worldwide. Currently, the only chance for obtaining a cure in patients with HCC is by either a surgical resection or liver transplantation.

25 Oct 2007

Potential new ways to treat ulcers

The alarming truth is more than 14.5 million people suffer from ulcers worldwide due to factors such as stress and the use of non-steroidal anti-inflammatory drugs (NSAIDS).

24 Oct 2007

Increased intestinal permeability by exogenous sphingomyelinase

Many signaling molecules involved in the pathogenesis of IBD, such as TNF or IFN, infections with bacteria or viruses and ionizing radiation, may cause an alteration of the lipid composition in the cell membrane by activation of sphingomyelinases (SMases).

24 Oct 2007

Experimental cancer pharmaceuticals under trial

A potent and selective inhibitor of the mitotic kinesin CENP-E (GSK923295A) demonstrates a novel mechanism of inhibiting tumor cell proliferation and shows activity against a broad panel of human tumor cell lines in vitro: Abstract A 111.

24 Oct 2007

Low-dose aspirin for in vitro fertilisation

Although it is inexpensive, easy to obtain and poses little health risk, women undergoing in vitro fertilization (IVF) cannot rely upon aspirin to help them become pregnant, according to a systematic review of nine studies.

23 Oct 2007

Experts warn women about experimental fertility options

The American Society for Reproductive Medicine (ASRM) has warned women that two experimental fertility procedures currently being offered remain unproven.

22 Oct 2007

New links in the cystic fibrosis chain uncover potential therapeutics

Cystic fibrosis (CF) is an inherited disease caused by mutations in the CFTR gene.

19 Oct 2007

New insight into mechanisms by which E. coli colonize the intestines

Food poisoning caused by the bacteria enterohemorrhagic Eschericia coli (EHEC) O157:H7A results in severe abdominal cramps and bloody diarrhea.

19 Oct 2007

In vitro models will minimize animal use in arthritis studies

It's hard to think of scientists in laboratories working toward solutions for medical problems without mice or other laboratory animals, but animals' roles in at least one major research laboratory may soon be minimal.

18 Oct 2007

Baicalin shows promise for severe acute pancreatitis

¡°Qingyitang¡±, a representative prescription of Traditional Chinese Medicine for SAP was widely used in the orients countries.

18 Oct 2007

In-vitro fertilization improved with 3-D/4-D-guided embryo transfer and new placement target

The pregnancy rate for patients undergoing in-vitro fertilization (IVF) is improved when doctors use advanced 3D/4D imaging to guide the placement of embryos to the point where the endometrium is most receptive to implantation, according to a study presented at the 63rd Annual Meeting of the American Society for Reproductive Medicine (ASRM).

17 Oct 2007

AngioGenex files patent on first small molecule Id-inhibitors

AngioGenex Inc. has identified and filed a patent application on small molecules that are potent inhibitors of the Id proteins.

17 Oct 2007

New insight into Herceptin resistance in breast cancer

A new study provides important insight into the mechanisms involved in resistance to treatment of breast cancer patients with trastuzumab (Herceptin). The research, published by Cell Press in the October issue of the journal Cancer Cell , identifies markers that may help to identify patients who are unlikely to respond to trastuzumab treatment and provides a potential strategy for treating these patients.

16 Oct 2007

HiFi DNA Tech files lawsuit against FDA

A lawsuit was filed Oct. 12 in U.S. District Court against the U.S. Department of Health and Human Services (HHS) and the U.S. Food and Drug Administration (FDA) related to reclassification of HPV DNA tests from class III to class II devices. The inaction by both agencies hinders introduction of new and affordable HPV testing to improve women’s health care.

15 Oct 2007

AMDL submits data to FDA for clearance to market its diagnostic test to monitor colorectal cancer patients

AMDL, Inc., developer and marketer of tests for the early detection of cancer and other serious diseases, announced today that it has filed with the U.S. Food & Drug Administration (FDA) for clearance to market its unique, proprietary DR-70 (FDP) ELISA tumor marker test for use as an aid in monitoring patients previously diagnosed with colorectal cancer. AMDL used the guidance provided at the meeting they had with the FDA on January 25, 2007.

15 Oct 2007

Feline virus, antiviral drug studied to understand drug resistance

Researchers at Ohio State will spend the next two years testing their theories about just how an AIDS-like virus in cats is able to resist the powerful medicines that are thrown against it.

10 Oct 2007

Dual action anthrax vaccine-antitoxin combination developed

The immune response generated in rats by the new agent protects against lethal toxin exposure after only one injection, and is faster and stronger than any currently available vaccine.

8 Oct 2007

Fraunhofer pharmaceutical agent speeds drug development

It takes a great deal of time and money to develop a new drug. At Biotechnica in Hanover from October 9 to 11, the Fraunhofer Life Sciences Alliance will demonstrate how a pharmaceutical agent can make its way more quickly from the research laboratory to the pharmacy.

8 Oct 2007

40,000 computers used to tackle bird flu in search for new anti-viral drug discoveries

Last month a collaboration of European and Asian researchers launched a new attack against the deadly bird flu virus, harnessing the combined power of more than 40,000 computers across 45 countries to boost the pace of anti-viral drug discovery.

4 Oct 2007