Cytokine News and Research

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Early safety and efficacy results on a contraceptive vaginal film that inactivates sperm

The current study aimed to explore the contraceptive potential of the human contraceptive antibody-containing vaginal film called ZB-06.

7 Mar 2023

Symptomatic COVID-19 is associated with deficits in task-related cognitive function and psychiatric symptoms

Researchers conducted a prospective population survey, functional brain imaging, and a cognitive task performance test to determine whether a history of symptomatic coronavirus disease 2019 (COVID-19) was associated with psychiatric and neurocognitive symptoms.

7 Mar 2023

Study identifies the essential genetic and immunologic perturbations occurring in patients with long COVID lung fibrosis

Researchers elucidated immunologic and genetic perturbations in long COVID patients with pulmonary fibrosis.

3 Mar 2023

Study identifies renalase as a novel independent predictor of COVID-19-related mortality

Researchers assessed the role of renalase as an independent predictor of COVID-19-related mortality.

2 Mar 2023

Researchers use spatial single-cell transcriptome technique to examine immune signatures of SARS-CoV-2-infected lungs

The study findings demonstrate the power of spatial single-cell transcriptomics in studying COVID-19 lung pathology and other health and disease conditions.

1 Mar 2023

Study reveals synergistic impact of estrogen and intestinal dysbiosis on pulmonary fibrosis

In a recent study published in Cells, researchers evaluated idiopathic pulmonary fibrosis (IPF) pathophysiological differences by sex and intestinal microbiome.

1 Mar 2023

Exploring the neuroprotective potential of cell-penetrating peptides, extracellular vesicles, and micro ribonucleic acids

In a recent review published in Biomedicines, researchers explored extracellular vesicles (EVs), cell-penetrating peptides (CPPs), and micro ribonucleic acids (miRNAs) as therapies for neurodegenerative diseases such as Alzheimer’s disease (AD) and Parkinson’s disease (PD).

1 Mar 2023

Study supports the concept of atherosclerosis as a T-cell autoimmune disease targeting the arterial wall

Researchers assessed T-cell tolerance checkpoints observed in atherosclerosis.

27 Feb 2023

A study of the effects of beta-alanine supplements on soldiers' performance

Researchers review the effects of β-alanine supplementation on soldiers’ performance, cognition, and resilience.

22 Feb 2023

First clinical trial of GABA/GAD focused exclusively on children with recent onset Type 1 diabetes

For the first time, humans with newly diagnosed Type 1 diabetes, or T1D, have received two treatments called GABA and GAD that have shown promise in animal studies and in isolated human pancreas islets. This investigator-initiated clinical trial, published in Nature Communications, focused exclusively on children with recent onset T1D.

22 Feb 2023

Dietary polyphenols may play a role in regulating inflammatory immune responses

PCB2DG, a polyphenol with anti-inflammatory properties, works by targeting and directly interacting with the major glutamine transporter protein, alanine serine cysteine transporter 2 (ASCT2), to inhibit the uptake of glutamine, an important amino acid found in the blood.

22 Feb 2023

A growing burden of alcoholic hepatitis

A recent study published in the journal Medical Clinics of North America discussed the diagnosis, treatment, and pathophysiology of alcoholic hepatitis (AH).

21 Feb 2023

Exploring the potential of betalain-engineered vegetables in conferring anti-inflammatory properties

Metabolic engineering is a field of plant biotechnology that seeks to genetically modify plant metabolic pathways to generate plant varieties with improved health benefits.

17 Feb 2023

Small molecule inhibitor reverses malignant hyper-editing by an inflammation-induced protein isoform

Researchers at University of California San Diego School of Medicine, Sanford Stem Cell Institute and Moores Cancer Center report that a late-stage, pre-clinical small molecule inhibitor, called rebecsinib, reverses malignant hyper-editing by an inflammation-induced protein isoform, known as ADAR1 p150.

16 Feb 2023

Delayed presentation of MIS-C following COVID-19

Researchers elucidate the pathophysiology of MIS-C and describe the probable reasons for the delayed presentation of the condition following COVID-19.

15 Feb 2023

Comparative study on retinoic acid-inducible gene-I of humans and bats

In a recent study posted to the bioRxiv* preprint server, researchers cloned and functionally characterized the virus ribonucleic acid (RNA) sensor, retinoic acid-inducible gene-I (RIG-I), from the microbat Myotis daubentonii (Yangochiroptera suborder) and the megabat Rousettus aegyptiacus (Yinpterochiroptera suborder), and compared them to the human ortholog.

15 Feb 2023

Cytokine News and Research

Early safety and efficacy results on a contraceptive vaginal film that inactivates sperm

Symptomatic COVID-19 is associated with deficits in task-related cognitive function and psychiatric symptoms

Study identifies the essential genetic and immunologic perturbations occurring in patients with long COVID lung fibrosis

Study identifies renalase as a novel independent predictor of COVID-19-related mortality

Researchers use spatial single-cell transcriptome technique to examine immune signatures of SARS-CoV-2-infected lungs

Study reveals synergistic impact of estrogen and intestinal dysbiosis on pulmonary fibrosis

Exploring the neuroprotective potential of cell-penetrating peptides, extracellular vesicles, and micro ribonucleic acids

Study supports the concept of atherosclerosis as a T-cell autoimmune disease targeting the arterial wall

A study of the effects of beta-alanine supplements on soldiers' performance

First clinical trial of GABA/GAD focused exclusively on children with recent onset Type 1 diabetes

Dietary polyphenols may play a role in regulating inflammatory immune responses

A growing burden of alcoholic hepatitis

Exploring the potential of betalain-engineered vegetables in conferring anti-inflammatory properties

Small molecule inhibitor reverses malignant hyper-editing by an inflammation-induced protein isoform

Delayed presentation of MIS-C following COVID-19

Comparative study on retinoic acid-inducible gene-I of humans and bats

New insights into the role of T-cells during long COVID

Casein-based diet found to protect diabetic mice against autoimmunity

Can lifestyle and nutrition be the answer for metabolic syndrome and type 2 diabetes remission?

Pregnancy outcomes after monoclonal antibodies infusion for COVID-19

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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