Immune Response News and Research

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MD Anderson Cancer Center's Jim Allison to receive Science of Oncology Award at ASCO 2015

The world's leading organization of oncologists will honor Jim Allison, Ph.D., for his pioneering research that led to a new way to treat cancer by unleashing an immune system attack rather than targeting tumors directly.

30 May 2015

Monoclonal antibody nivolumab improves survival rates of melanoma patients

The monoclonal antibody nivolumab has shown promise as a therapeutic agent, particularly by improving the survival rates of melanoma patients. Jeffrey S. Weber, M.D., Ph.D., director of the Donald A. Adam Comprehensive Melanoma Research Center at Moffitt Cancer Center will be presenting data from a retrospective analysis of the safety of nivolumab in 4 ongoing phase I-III studies in melanoma patients at the 2015 American Society of Clinical Oncology Annual Meeting in Chicago.

29 May 2015

MEDI4736 and tremelimumab combination shows acceptable safety, potential efficacy in NSCLC patients

Advanced non-small cell lung cancer (NSCLC) patients have few effective treatment options and low 5-year survival rates. The checkpoint inhibitors MEDI4736 and tremelimumab have both demonstrated acceptable safety and potential efficacy when used as single-agents in several different types of cancer.

29 May 2015

Novel discovery offers new insight into why women more likely than men to develop MS

An innocent mistake made by a graduate student in a Northwestern Medicine lab (she accidentally used male mice instead of female mice during an experiment) has led scientists to a novel discovery that offers new insight into why women are more likely than men to develop autoimmune diseases such as multiple sclerosis (MS).

28 May 2015

Researchers suggest new target for treating BRAF inhibitor-resistant melanoma tumors

A new collaborative study led by researchers at Sanford-Burnham Medical Research Institute, published today in Cell Reports, provides new insight into the molecular changes that lead to resistance to a commonly prescribed group of drugs called BRAF inhibitors.

28 May 2015

Novel survey shows high rates of tattoo-related infection, itching and swelling in New Yorkers

In what they believe to be the first survey of its kind in the United States, researchers at NYU Langone Medical Center have found that as many as 6 percent of adult New Yorkers who get "inked" — in other words, those who get a tattoo — have experienced some form of tattoo-related rash, severe itching or swelling that lasted longer than four months and, in some cases, for many years.

28 May 2015

Study: Drugs that block NPC1 protein could be used to treat Ebola virus disease

A new study has demonstrated that a protein called Niemann-Pick C1 (NPC1) is critical for the Ebola virus to infect a host. The study, published in the May/June issue of mBio, the online open-access journal of the American Society for Microbiology, suggests that drugs that block NPC1 could be used to treat this deadly disease.

27 May 2015

TGen and Baylor partnership set to increase treatment options for cancer patients

The Translational Genomics Research Institute (TGen) and Baylor Research Institute (BRI) at Dallas today announce an agreement that will focus on accelerating early detection and treatments for patients with a broad range of cancers.

22 May 2015

Study explores how our intestinal tract changes as we age

Scientists and clinicians on the Norwich Research Park have carried out the first detailed study of how our intestinal tract changes as we age, and how this determines our overall health.

22 May 2015

Johns Hopkins scientists safely use immune cells to treat multiple myeloma

In a report on what is believed to be the first small clinical trial of its kind, researchers at the Johns Hopkins Kimmel Cancer Center say they have safely used immune cells grown from patients' own bone marrow to treat multiple myeloma, a cancer of white blood cells.

21 May 2015

Research shows how immune system controls biological clock in times of inflammation, infection

Researchers at Trinity College Dublin and the University of Pennsylvania have uncovered an important link between our body clock and the immune system that will have relevance to the treatment of inflammatory and infectious diseases.

20 May 2015

Researchers uncover major link between human body clock and immune system

An important link between the human body clock and the immune system has relevance for better understanding inflammatory and infectious diseases, discovered collaborators at the Perelman School of Medicine at the University of Pennsylvania and Trinity College, Dublin.

19 May 2015

Machine learning can predict emerging infectious diseases

Machine learning can pinpoint rodent species that harbor diseases and geographic hotspots vulnerable to new parasites and pathogens. So reports a new study in the Proceedings of the National Academy of Sciences led by Barbara A. Han, a disease ecologist at the Cary Institute of Ecosystem Studies.

19 May 2015

MIT researchers find way to develop implantable devices that can avoid scar-tissue buildup

Biomedical devices that can be implanted in the body for drug delivery, tissue engineering, or sensing can help improve treatment for many diseases. However, such devices are often susceptible to attack by the immune system, which can render them useless.

19 May 2015

Men with a history of asthma less likely to have aggressive prostate cancer

In what they are calling a surprising finding in a large study of men who completed questionnaires and allowed scientists to review their medical records, Johns Hopkins researchers report that men with a history of asthma were less likely than those without it to develop lethal prostate cancer.

19 May 2015

Men with asthma less likely to develop lethal prostate cancer

Scientists found that men with a history of asthma were 29 percent less likely to have been diagnosed with prostate cancer that spread or to have died of their prostate cancer...

14 May 2015

TSRI researchers find interferon beta protein as prime suspect in persistent viral infections

Interferon proteins are normally considered virus-fighters, but scientists at The Scripps Research Institute have found evidence that one of them, interferon beta (IFNβ), has an immune-suppressing effect that can help some viruses establish persistent infections.

14 May 2015

Research finding could lead to better treatments for inflammatory bowel disease

Inflammatory bowel disease (IBD) afflicts 1.6 million people in the United States, causing abdominal pain, diarrhea, constipation, rectal bleeding and other potentially debilitating symptoms.

14 May 2015

Australian researchers discover rogue germinal centre B cells that trigger autoimmune disease

Australian researchers believe they have discovered a group of cells that trigger autoimmune disease, as well as the molecular 'trigger guard' that normally holds them in check.

13 May 2015

Research paves way for development of individualized immunotherapy for treating cancer

Mainz-based researchers have made significant advances with regard to the development of individualized immunotherapy strategies for treating cancer. They have managed to identify the relevant genetic changes or mutations associated with various types of cancer and have determined their individual blueprints.

13 May 2015

Immune Response News and Research

MD Anderson Cancer Center's Jim Allison to receive Science of Oncology Award at ASCO 2015

Monoclonal antibody nivolumab improves survival rates of melanoma patients

MEDI4736 and tremelimumab combination shows acceptable safety, potential efficacy in NSCLC patients

Novel discovery offers new insight into why women more likely than men to develop MS

Researchers suggest new target for treating BRAF inhibitor-resistant melanoma tumors

Novel survey shows high rates of tattoo-related infection, itching and swelling in New Yorkers

Study: Drugs that block NPC1 protein could be used to treat Ebola virus disease

TGen and Baylor partnership set to increase treatment options for cancer patients

Study explores how our intestinal tract changes as we age

Johns Hopkins scientists safely use immune cells to treat multiple myeloma

Research shows how immune system controls biological clock in times of inflammation, infection

Researchers uncover major link between human body clock and immune system

Machine learning can predict emerging infectious diseases

MIT researchers find way to develop implantable devices that can avoid scar-tissue buildup

Men with a history of asthma less likely to have aggressive prostate cancer

Men with asthma less likely to develop lethal prostate cancer

TSRI researchers find interferon beta protein as prime suspect in persistent viral infections

Research finding could lead to better treatments for inflammatory bowel disease

Australian researchers discover rogue germinal centre B cells that trigger autoimmune disease

Research paves way for development of individualized immunotherapy for treating cancer

Understanding the DNA Damage Response in Innate Immunity eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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