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Vagus nerve stimulation may be a potential adjunct therapy for COVID-19

COVID-19 was initially described as lung inflammation, or pneumonia, in older adults. However, we now know that SARS-CoV-2 infections can cause a wide range of symptoms in people of all ages, ranging from no symptoms at all to systemic inflammation and even death.

27 May 2021

Protein-RNA interactions in SARS-CoV-2-infected cells reveal key regulators of infection

Researchers in the UK, including the University of Oxford and Glasgow, as well as the University of Heidelberg, published their analysis of protein-RNA interactions in SARS-CoV-2 and the subsequent significance in the journal Molecular Cell. This research could help to uncover novel antiviral strategies for COVID-19 due to a broader understanding of how the virus works.

27 May 2021

Study sheds new light on complex dynamics involved in microbial infections

Included in the vast fallout stemming from the COVID-19 pandemic, scientists are paying closer attention to microbial infections and how life forms defend against attacks from pathogens.

27 May 2021

Astodrimer sodium exhibits potent virucidal and antiviral activity against SARS-CoV-2 in vitro

Researchers from the US and Australia recently conducted some studies to assess the in vitro antiviral and virucidal (irreversible) activity of astodrimer sodium against SARS-CoV-2.

26 May 2021

Neurocognitive symptoms persist 6 months post-infection with long COVID

According to the World Health Organization (WHO), COVID-19 long-haulers are people who experience symptoms such as body ache, fatigue, shortness of breath, headache, difficulty concentrating, loss of taste or smell, or other health issues long after they test negative for the virus. It can be defined as having serious and prolonged symptoms three months after severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection.

26 May 2021

Disproportionate number of SARS-CoV-2 breakthrough infections are caused by variants of concern

A study conducted by researchers in the United States has shown that among twenty patients with breakthrough infection following vaccination against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) – the agent that causes coronavirus disease 2019 (COVID-19) – all of the infections were caused by variants of concerns.

26 May 2021

Reducing COVID-19 burden with monoclonal antibodies and vaccination

Researchers in the United States, the UK and France have shown that using antiviral monoclonal antibodies in combination with vaccination can be expected to suppress the transmission of severe acute respiratory syndrome coronavirus 2 (SARS CoV-2) and reduce the burden of coronavirus disease 2019 (COVID-19) more than vaccination alone.

26 May 2021

Will SARS-CoV-2 eventually become just another seasonal coronavirus?

Could SARS-CoV-2 become just a seasonal nuisance in the next decade, causing just coughs and sniffles like a common cold, suggests new research? Scientists at the University of Utah, USA, tried to predict the possible future of the novel coronavirus using mathematical models that use learnings from the current pandemic on changes in human immunity over time.

26 May 2021

CASdetec: new CRISPR-based SARS-CoV-2 detection platform detects nucleic acids with high sensitivity and specificity

To add to existing CRISPR-based nucleic acid detection protocols, a team of researchers recently established a new SARS-CoV-2 detection protocol based on their previously reported platform - CDetection (Cas12b-mediated DNA detection). They combined nucleic-acid amplification methods and sample treatment protocols with CDetection and established an integrated nucleic acid detection platform called CRISPR-assisted detection or CASdetec. CASdetec has a detection limit of 1×104 copies/mL for SARS-CoV-2 pseudovirus, without any observed cross-reactivity.

26 May 2021

New COVID-19 test can deliver highly accurate results in less than 15 minutes

A new rapid coronavirus test developed by KAUST scientists can deliver highly accurate results in less than 15 minutes.

26 May 2021

Intensity and duration of SARS-CoV-2 immunity may depend on ABO blood group

A team of scientists from Canada and Spain recently evaluated the durability of antigen-specific immune responses in COVID-19 recovered individuals. They have also identified potential host factors associated with robust and long-lasting anti-SARS-CoV-2 immunity.

26 May 2021

Researchers develop a method to detect SARS-CoV-2 and variants simultaneously

Researchers demonstrate a method of detecting the presence and mutations in the SARS-CoV-2 virus using the smaller and cheaper Oxford Nanopore sequencer, a method they believe could make pandemic surveillance faster and cheaper.

26 May 2021

Could GRP78 be a therapeutic target against COVID-19?

A new study by a team of researchers at the Keck School of Medicine, University of Southern California, USA, reports a potentially important therapeutic target in the form of a molecule called GRP78 that promotes the entry and protein production by many viruses. The team's paper has been published in the Journal of Biological Chemistry.

26 May 2021

New SARS-CoV-2 variants emerge among children in United States, suggests study

As the coronavirus disease 2019 (COVID-19) pandemic approaches its eighteenth month, new variants of concern (VOCs) of the causative pathogen – severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) – continue to emerge all over the world. A new study explores the emergence of such VOCs among young children, below 12 years of age, and the potential consequences of this phenomenon.

26 May 2021

Tissue-resident memory T cells found in lungs of people who had COVID-19 10 months ago

In recent research by Judith Grau-Expósito et al., scientists identify circulating virus-specific T cell responses during acute SARS-CoV-2 infection with functional, migratory, and apoptotic patterns modulated by viral proteins and associated with clinical outcome.

26 May 2021

Zoonotic and vector-borne emerging tropical diseases pose a constant threat

A recent article published in the journal Frontiers in Tropical Diseases assessed the threat of emerging zoonotic and vector-borne tropical diseases.

26 May 2021

Poor sleep impacts risk of long-term cognitive decline in Hispanic/Latino adults

Poor sleep impacts the risk of long-term cognitive decline in Hispanic/Latino middle aged and older adults differently than it does in non-Hispanic adults, according to research led by University of Miami Miller School of Medicine neurology faculty and the largest long-term study of U.S. Hispanic/Latinos to date.

26 May 2021

Syndrome News and Research

Vagus nerve stimulation may be a potential adjunct therapy for COVID-19

Protein-RNA interactions in SARS-CoV-2-infected cells reveal key regulators of infection

Study sheds new light on complex dynamics involved in microbial infections

Astodrimer sodium exhibits potent virucidal and antiviral activity against SARS-CoV-2 in vitro

Neurocognitive symptoms persist 6 months post-infection with long COVID

Disproportionate number of SARS-CoV-2 breakthrough infections are caused by variants of concern

Reducing COVID-19 burden with monoclonal antibodies and vaccination

Will SARS-CoV-2 eventually become just another seasonal coronavirus?

CASdetec: new CRISPR-based SARS-CoV-2 detection platform detects nucleic acids with high sensitivity and specificity

New COVID-19 test can deliver highly accurate results in less than 15 minutes

Intensity and duration of SARS-CoV-2 immunity may depend on ABO blood group

Researchers develop a method to detect SARS-CoV-2 and variants simultaneously

Could GRP78 be a therapeutic target against COVID-19?

New SARS-CoV-2 variants emerge among children in United States, suggests study

Tissue-resident memory T cells found in lungs of people who had COVID-19 10 months ago

Zoonotic and vector-borne emerging tropical diseases pose a constant threat

Poor sleep impacts risk of long-term cognitive decline in Hispanic/Latino adults

Postmenopausal women who underwent bilateral oophorectomy have increased risk of carpal tunnel syndrome

Researchers identify mechanism that may lead to new therapies for strokes, brain injuries

Previous H3N2 influenza A infection may explain some cases of severe COVID-19

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