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Study provides more nuanced insights into RNA modifications by A-to-I editing during brain development

Mount Sinai researchers have cataloged thousands of sites in the brain where RNA is modified throughout the human lifespan in a process known as adenosine-to-inosine (A-to-I) editing, offering important new avenues for understanding the cellular and molecular mechanisms of brain development and how they factor into both health and disease.

1 Nov 2022

UT Southwestern study uncovers a causative signaling pathway in breast cancer

UT Southwestern researchers have identified a causative signaling pathway in breast cancer, providing potential new targets for treatment of the most common type of cancer in women.

1 Nov 2022

Social and economic inequality associated with differences in children's brain connections

Growing up in a socioeconomically disadvantaged household may have lasting effects on children's brain development, a large new study suggests.

1 Nov 2022

EULAR points-to-consider can guide diagnostic evaluation, treatment and monitoring of SAIDs

SAIDs are a group of multi-system disorders caused by dysfunction in the innate immune system. A number of these SAIDs are mediated by a cytokine called interleukin-1 (IL-1), including the cryopyrin-associated periodic syndromes (CAPS), tumor necrosis factor receptor-associated periodic syndrome (TRAPS), mevalonate kinase deficiency (MKD), and deficiency of the IL-1 receptor antagonist (DIRA).

1 Nov 2022

Dietary components do not have impact on RMD outcomes

In 2022, EULAR - the European Alliance of Rheumatology Associations - published new recommendations regarding lifestyle behaviors and work participation to prevent progression of rheumatic and musculoskeletal diseases (RMDs).

1 Nov 2022

PROMs data infrequently accessed by members of clinical care, study suggests

Even when patient-reported outcome measures (PROMs) are successfully incorporated into electronic health records (EHRs), these patient-centered data are infrequently accessed by members of clinical care teams, suggests a study in the November/December issue of American Journal of Medical Quality, official journal of the American College of Medical Quality.

1 Nov 2022

Delta waves may be useful for diagnosing concussions in younger patients

Measuring levels of a specific brain wave could lead to more objective, definitive methods of diagnosing concussions and determining when young athletes can safely return to play, according to a UT Southwestern study.

1 Nov 2022

Rockefeller Foundation announces $3 million in new funding for Global.health

The Rockefeller Foundation has announced $3 million in new funding for Global.health (G.h) - a first-of-its-kind, open-source platform for scientific pandemic data.

1 Nov 2022

Experts analyze the physical activity and health of children prior to COVID-19

The COVID-19 pandemic has exacerbated shortfalls in children's physical activity around the world, according to a new study – and Scotland is not exempt.

1 Nov 2022

Research could lead to better postoperative care for patients who need shoulder arthroplasty revisions

The most common bacterial infection to occur after revision shoulder arthroplasty surgery can be diagnosed more accurately by considering how quickly samples of the microbe grow in hospital labs and the level of bacteria that grows, a study partly performed at UT Southwestern shows.

31 Oct 2022

BCRF renews funding to support the development of novel therapeutics for triple-negative breast cancer

The Breast Cancer Research Foundation (BCRF) has renewed its funding to Elisa Port, MD, and Hanna Irie, MD, PhD, to study new therapeutic approaches that target aggressive triple-negative breast cancer.

31 Oct 2022

Social protection program shows promise in helping poor households deal with natural disasters

An interventional social protection program called Program Keluarga Harapan (PKH) shows positive results in helping poor households develop proactive coping strategies before and during natural disasters, leading to social and economic resilience.

31 Oct 2022

Study expands breast cancer patient population that can benefit from PARP inhibitors

A drug approved to treat breast cancer patients with mutations in the BRCA1 or BRCA2 genes may also benefit people who have other genetic mutations.

31 Oct 2022

IHV researchers receive $7.5 million to control cancer among people living with HIV in sub-Saharan Africa

Institute of Human Virology researchers at the University of Maryland School of Medicine (UMSOM) have received two five-year awards from the National Institutes of Health's National Cancer Institute (NCI) for a total of $7.5 million.

31 Oct 2022

Researchers use AI to predict compounds that could neutralize baldness

Hair loss is undesirable for many men - and women - because one's hairstyle is often closely tied to their self-confidence.

31 Oct 2022

Study highlights lack of representation of non-English speakers in pediatrics research

A new analysis of U.S.-based pediatrics research published over the last decade found that just 9% of studies included non-English-speaking children or families, highlighting a lack of representation that could have serious implications for health equity.

31 Oct 2022

UH PREMIER Center receives funding to fight the rising tide of opioid addiction and death

Fighting the rising tide of opioid addiction and death, the Prescription Drug Misuse Education and Research (PREMIER) Center at the University of Houston College of Pharmacy has been funded for the next two years by the Texas Health and Human Services Commission for an additional $3.34 million.

31 Oct 2022

New hearing screening system for newborns uses a smartphone and low-cost earbuds

Newborns across the United States are screened to check for hearing loss. This test is important because it helps families better understand their child's health, but it's often not accessible to children in other countries because the screening device is expensive.

31 Oct 2022

Marital stress may impact young adults' recovery after a heart attack

A stressful marriage may negatively impact heart attack recovery. Marital stress among younger adults (ages 18–55 years) was linked to worse recovery after a heart attack.

31 Oct 2022

COVID-19-positive donor hearts appear to be safe for transplantation

Donor hearts from people who were COVID-19-positive appeared to be as safe for transplantation as those from people without COVID-19, according to a short-term analysis to be presented at the American Heart Association's Scientific Sessions 2022.

31 Oct 2022

Education News and Research

Study provides more nuanced insights into RNA modifications by A-to-I editing during brain development

UT Southwestern study uncovers a causative signaling pathway in breast cancer

Social and economic inequality associated with differences in children's brain connections

EULAR points-to-consider can guide diagnostic evaluation, treatment and monitoring of SAIDs

Dietary components do not have impact on RMD outcomes

PROMs data infrequently accessed by members of clinical care, study suggests

Delta waves may be useful for diagnosing concussions in younger patients

Rockefeller Foundation announces $3 million in new funding for Global.health

Experts analyze the physical activity and health of children prior to COVID-19

Research could lead to better postoperative care for patients who need shoulder arthroplasty revisions

BCRF renews funding to support the development of novel therapeutics for triple-negative breast cancer

Social protection program shows promise in helping poor households deal with natural disasters

Study expands breast cancer patient population that can benefit from PARP inhibitors

IHV researchers receive $7.5 million to control cancer among people living with HIV in sub-Saharan Africa

Researchers use AI to predict compounds that could neutralize baldness

Study highlights lack of representation of non-English speakers in pediatrics research

UH PREMIER Center receives funding to fight the rising tide of opioid addiction and death

New hearing screening system for newborns uses a smartphone and low-cost earbuds

Marital stress may impact young adults' recovery after a heart attack

COVID-19-positive donor hearts appear to be safe for transplantation

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