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Study offers insight into molecular biology of the brain in bipolar disorder patients

In a comprehensive study involving one of the largest-ever samples of post-mortem brains, scientists at the Lieber Institute for Brain Development, in collaboration with researchers at the Johns Hopkins School of Medicine and Bloomberg School of Public Health, have pinpointed significant differences in gene expression in two specific regions of the brains of hundreds of patients who had bipolar disorder.

7 Mar 2022

Slowing down the DNA replication speed increases cell reprogramming efficiency

Adult cells in our body can only give rise to the same cell type. For example, a skin cell cannot give rise to a muscle cell but to skin cells only.

7 Mar 2022

NETosis in COVID-19 and MIS-C

A new study investigates the role played by neutrophil extracellular traps formation and degradation in COVID-19.

7 Mar 2022

Study to examine the risks for brain disorders from repetitive head impacts in contact sports

Internationally-renowned researchers from Boston University and the University of California, San Francisco) are launching a new study, called the Head Impact & Trauma Surveillance Study (HITSS).

7 Mar 2022

Small change approach not more effective than monitoring alone in preventing weight gain

Managing overweight and obesity is challenging, and a new randomized controlled trial found that, contrary to earlier evidence, making small changes to caloric intake and physical activity levels did not prevent long-term weight gain better than monitoring alone.

7 Mar 2022

$20 million scientific research initiative focuses on disparities in maternal-infant heart health

Poor heart health, especially among women of color, puts both mothers-to-be and their infants at risk, with heart disease causing more than one in four pregnancy-related deaths (26.5%) in the U.S., according to the American Heart Association Heart Disease and Stroke Statistics 2022 Update.

6 Mar 2022

A special surgical microscope to illuminate blood, bacterial biofilms, cartilage, and soft tissue

Inflammation of the middle ear is often triggered a cholesteatoma, an aggressive form of chronic otitis media. In order to detect cholesteatomas and bacterial biofilms and to remove them safely, the new collaborative project 'BetterView' is working on a special surgical microscope.

4 Mar 2022

Health literacy among migrants found to be similar to that of general population

Health literacy plays a decisive role in reaching old age in good health. Low health literacy contributes to behaviors like being sedentary and not exercising, eating a less nutritious diet, taking more medications, and using healthcare services more often.

4 Mar 2022

Community-based approach to genetic testing may have beneficial effects, study finds

In 2010, scientists discovered that African Americans who are born with certain variants of a gene called apolipoprotein L1 (APOL1) have a higher-than-average risk for experiencing chronic kidney disease (CKD).

4 Mar 2022

Early menarche associated with chronic pain outcomes in women

Women who were younger at the time of their first menstrual period (menarche) are more likely to report chronic pain in adulthood, reports a study in PAIN®, the official publication of the International Association for the Study of Pain. The journal is published in the Lippincott portfolio by Wolters Kluwer.

4 Mar 2022

Gas chromatography-ion mobility spectrometry helps diagnose COVID-19 and predict disease severity

Researchers assess the ability of GC-IMS to differentiate between COVID-19 and other respiratory infections, as well as predict disease severity.

4 Mar 2022

Researchers identify genetic link between lymphatic disorder and stillbirth

In a world first discovery, South Australian researchers have identified a genetic mutation responsible for a lymphatic disorder that may cause stillbirth or severe, chronic disease in affected children.

4 Mar 2022

Long-acting monoclonal antibody shows potential to offer RSV protection for all infants

Nirsevimab showed 74.5 percent efficacy against medically attended lower respiratory tract infections caused by respiratory syncytial virus (RSV) in healthy infants, according to an international, randomized, placebo-controlled Phase 3 clinical trial.

3 Mar 2022

Home blood pressure monitoring may provide the basis for accurate diagnoses of hypertension

Blood pressure measurements routinely taken at home are more likely to provide the basis for accurate diagnoses of hypertension than those taken in a clinic setting, according to a new study led by Kaiser Permanente investigators.

3 Mar 2022

Taller adults may be more likely to develop colorectal cancer, study finds

A new meta-analysis, or data examination of several independent studies, by Johns Hopkins Medicine researchers adds to evidence that taller adults may be more likely than shorter ones to develop colorectal cancer or colon polyps that can later become malignant.

3 Mar 2022

Proactive machine learning models could speed data collection and analysis in healthcare

Shifting machine learning workflows to a proactive model could speed data collection and analysis in healthcare, according to a viewpoint article published in JAMA.

3 Mar 2022

Long or irregular menstrual cycles may be linked with increased risk of NAFLD

Women with long or irregular periods are known to have a higher risk of type 2 diabetes and heart disease, but researchers found these women may also be at risk for nonalcoholic fatty liver disease (NAFLD), according to a new study published in the Endocrine Society's Journal of Clinical Endocrinology and Metabolism.

3 Mar 2022

Chronic News and Research

Study offers insight into molecular biology of the brain in bipolar disorder patients

Slowing down the DNA replication speed increases cell reprogramming efficiency

NETosis in COVID-19 and MIS-C

Study to examine the risks for brain disorders from repetitive head impacts in contact sports

Small change approach not more effective than monitoring alone in preventing weight gain

$20 million scientific research initiative focuses on disparities in maternal-infant heart health

A special surgical microscope to illuminate blood, bacterial biofilms, cartilage, and soft tissue

Health literacy among migrants found to be similar to that of general population

Community-based approach to genetic testing may have beneficial effects, study finds

Early menarche associated with chronic pain outcomes in women

Gas chromatography-ion mobility spectrometry helps diagnose COVID-19 and predict disease severity

Researchers identify genetic link between lymphatic disorder and stillbirth

Long-acting monoclonal antibody shows potential to offer RSV protection for all infants

Home blood pressure monitoring may provide the basis for accurate diagnoses of hypertension

Taller adults may be more likely to develop colorectal cancer, study finds

Proactive machine learning models could speed data collection and analysis in healthcare

Long or irregular menstrual cycles may be linked with increased risk of NAFLD

Incidence and outcomes of breakthrough SARS-CoV-2 infections in vaccinated chronic liver disease patients

WHO experts suggest antiviral drug for patients with non-severe covid-19 at highest risk of hospitalization

Study illustrates the link between e-cigarette use and increased odds of prediabetes

Industry Focus eBook - Neurology/Neuroscience - 2nd edition eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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