Cytokine News and Research

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Exploring the biomarker profiles in severe COVID-19

In new research, researchers estimated the D-dimer levels and characterized lymphocyte subsets and cytokine profiles in severe coronavirus disease 2019 (COVID-19) patients.

7 Oct 2022

Intranasal vaccine represents an effective broad-spectrum COVID-19 vaccine strategy

Researchers evaluated the efficacy of dNS1-RBD, a novel intranasal COVID-19 vaccine.

6 Oct 2022

What is the impact of monkeypox infection on the hemostatic system?

In a recent study, researchers determined if monkeypox (MPX) infection affected the hemostatic system like that observed in coronavirus disease 2019 (COVID-19).

6 Oct 2022

Three-dimensional in vitro model to reproduce COVID-19-induced endothelial dysfunction

In a new study, researchers developed a three-dimensional (3D) in vitro tissue model to assess the effects of SARS-CoV-2 on the vascular endothelial cells.

5 Oct 2022

Novel protein vaccine NVX-CoV2373 triggered functional T cell responses to SARS-CoV-2

Researchers determined the T cell response to the NVX-CoV2373, an adjuvanted recombinant full-length SARS-CoV-2 spike (S) trimer protein vaccine.

5 Oct 2022

Study shows SARS-CoV-2 infects human adipose tissue and undergoes productive infection in fat cells

Researchers demonstrated infection of human adipose tissue by SARS-CoV-2.

5 Oct 2022

Study provides insight into cellular and molecular mechanisms involved in COVID-19 delirium

Researchers from King's College London have shown that when brain cells are directly exposed to blood taken from COVID-19 patients with delirium, there is an increase in cell death and a decrease in the generation of new brain cells.

5 Oct 2022

Omicron reduces host antibody response by lower B-cell antigenicity

A new study explores the functional relevance of some Omicron mutations in terms of their ability to escape neutralizing antibody responses.

4 Oct 2022

How COVID-19 affects the female reproductive system

A new review in the Biology of Reproduction journal analyzed the relationship between the immune system and the female reproductive system while focusing on the effects of COVID-19-associated immune responses on the reproductive system. The study searched PubMed to identify peer-reviewed literature in English up to May 2022 and finally included 83 studies.

3 Oct 2022

Novel peanut-specific human IgE monoclonal antibodies may uncover new therapeutic targets for peanut allergy

A recent Frontiers in Immunology journal study by University of North Carolina at Chapel Hill and Vanderbilt University researchers has created an in vitro system to determine potential therapeutics targeting sensitized effector cells based on human, allergen-specific, Immunoglobulin E (IgE) monoclonal antibodies (mAbs).

2 Oct 2022

Study establishes a feasible combination therapeutic strategy for ulcerative colitis

Despite recent advancements in our knowledge of the pathogenic mechanisms of ulcerative colitis, there is still a considerable unmet medical need for the treatment of ulcerative colitis.

29 Sep 2022

CAR T-cell therapy produces impressive results in first clinical trial in patients with multiple myeloma

A therapy made of immune system T cells engineered to target a somewhat enigmatic cell protein called GPRC5D antigen produced impressive results in its first clinical trial in patients with multiple myeloma, researchers at Memorial Sloan Kettering Cancer Center (MSK), Dana-Farber Cancer Institute and Roswell Park Comprehensive Cancer Center report in a new study published today by the New England Journal of Medicine.

29 Sep 2022

Insights into the biology of virtual memory CD8+ T cells

Virtual memory CD8+ T cells (TVM) are a relatively recent discovery in humans. A new review discusses what is known about them from mouse models and their cellular equivalents in humans, as described in the peer-reviewed Journal of Interferon & Cytokine Research.

28 Sep 2022

Study finds dimethyl fumarate was not associated with an improvement in clinical outcomes in adults hospitalized with COVID-19

Researchers evaluated the efficacy of the anti-inflammatory drug dimethyl fumarate in treating COVID-19 as part of an early phase, randomized, controlled assessment trial in the UK.

28 Sep 2022

How the gut microbiome could affect COVID-19 severity

Researchers review the potential role of the gut microbiome in determining severe COVID-19.

27 Sep 2022

Study characterizes immunological signature of SARS-CoV-2 infection in children

A recent study has demonstrated that the clinical severity of COVID-19 in children depends on the dynamics of immune response induced by SARS-CoV-2 infection.

26 Sep 2022

Systemic inflammation triggered by SARS-CoV-2 found to cause human testicular injury

In a new study, a team of researchers demonstrated that testicular injury in humans is not due to direct SARS-CoV-2 infection but more likely is an indirect effect of exposure to systemic inflammation or SARS-CoV-2 antigens.

26 Sep 2022

The impact of sleep fragmentation on the clonal diversity of immune cells and the genetic aging of the hematopoietic system

A new study shows that sleep does much more, regulating the normal production of blood cells. This finding underlines how essential a healthy sleep routine is for a normal life.

26 Sep 2022

Study reveals a testable hypothesis to explain the initiation of autoimmunity in T1D patients

Type 1 diabetes (T1D) is an autoimmune disease in which the pancreas makes little or no insulin. The details on the events that occur during autoimmune destruction of the pancreatic beta-cells have been studied extensively yet the mystery of what causes autoimmunity is unknown.

23 Sep 2022

Study describes the dynamics of immune responses to triple COVID-19 vaccination

The effectiveness of the three-dose COVID-19 vaccination against SARS-CoV-2 and its variants has been described in detail in a recent study.

23 Sep 2022

Cytokine News and Research

Exploring the biomarker profiles in severe COVID-19

Intranasal vaccine represents an effective broad-spectrum COVID-19 vaccine strategy

What is the impact of monkeypox infection on the hemostatic system?

Three-dimensional in vitro model to reproduce COVID-19-induced endothelial dysfunction

Novel protein vaccine NVX-CoV2373 triggered functional T cell responses to SARS-CoV-2

Study shows SARS-CoV-2 infects human adipose tissue and undergoes productive infection in fat cells

Study provides insight into cellular and molecular mechanisms involved in COVID-19 delirium

Omicron reduces host antibody response by lower B-cell antigenicity

How COVID-19 affects the female reproductive system

Novel peanut-specific human IgE monoclonal antibodies may uncover new therapeutic targets for peanut allergy

Study establishes a feasible combination therapeutic strategy for ulcerative colitis

CAR T-cell therapy produces impressive results in first clinical trial in patients with multiple myeloma

Insights into the biology of virtual memory CD8+ T cells

Study finds dimethyl fumarate was not associated with an improvement in clinical outcomes in adults hospitalized with COVID-19

How the gut microbiome could affect COVID-19 severity

Study characterizes immunological signature of SARS-CoV-2 infection in children

Systemic inflammation triggered by SARS-CoV-2 found to cause human testicular injury

The impact of sleep fragmentation on the clonal diversity of immune cells and the genetic aging of the hematopoietic system

Study reveals a testable hypothesis to explain the initiation of autoimmunity in T1D patients

Study describes the dynamics of immune responses to triple COVID-19 vaccination

Industry Focus eBook - Cell biology (5th edition) eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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