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Multiple withdrawal symptoms experienced by people using medical marijuana for chronic pain

More than half of people who use medical marijuana products to ease pain also experience clusters of multiple withdrawal symptoms when they're between uses, a new study finds.

8 Jan 2021

Vanderbilt researcher proposes an explanatory paradigm for the cause of autism

A unifying explanation of the cause of autism and the reason for its rising prevalence has eluded scientists for decades, but a theoretical model published in the journal Medical Hypotheses describes the cause as a combination of socially valued traits, common in autism, and any number of co-occurring disabilities.

8 Jan 2021

How do SARS-CoV-2 antibodies change over time in recovered patients?

Researchers studied convalescent plasma from recovered coronavirus disease 2019 (COVID-19) patients, with samples collected up to 34 weeks after recovery. They found IgG antibodies gradually declined with a median half-life of about 60 days.

8 Jan 2021

Airborne transmission of SARS-CoV-2 is possible in enclosed environments, a study finds

A team of scientists recently revealed that inside a closed room, the chance of airborne SARS-CoV-2 infection directly depends on the number of symptomatic COVID-19 patients in the room and the duration of exposure.

8 Jan 2021

Researchers develop a low-cost, saliva-optimized RT-LAMP assay for faster detection of SARS-CoV-2

SARS-CoV-2 pandemic has highlighted the shortcomings in emergency response globally and has driven a massive demand for in vitro diagnostic testing technologies. In order to address these issues, researchers from the US recently used the new pH dye LAMPShade Violet (LSV) in RT-LAMP. LSV has better visual contrast between high and low pH and a stronger inflection point, both of which enable easy interpretation of results and reduces ambiguity.

8 Jan 2021

C-Path PRO Consortium measure now included in FDA-approved label claim

Critical Path Institute's (C-Path) Patient-Reported Outcome (PRO) Consortium announces that clinical study results using the Consortium's Diary for Irritable Bowel Syndrome Symptoms-Constipation (DIBSS-C) were recently included in the expanded label for the drug LINZESS® (linaclotide).

7 Jan 2021

Link between fever, diarrhea, severe COVID-19, and persistent anti-SARS-CoV-2 antibodies

A new preprint research paper appearing on the medRxiv server describes a link between the persistence of neutralizing antibodies against the virus, disease severity, and specific COVID-19 symptoms.

7 Jan 2021

High-affinity SARS-CoV-2 RBD drives mutation spread, forms basis of new COVID-19 inhibitor

Now, an intriguing recent study appeared on the bioRxiv * preprint server describes the use of in vitro evolution to elicit affinity maturation of the viral receptor-binding domain (RBD) of the spike protein to bind the host cell angiotensin-converting enzyme 2 (ACE2) with greater affinity.

7 Jan 2021

IU research findings could prevent common complication of blood stem cell transplantation in leukemia

Researchers at the Indiana University Melvin and Bren Simon Comprehensive Cancer Center published promising findings today in the New England Journal of Medicine on preventing a common complication to lifesaving blood stem cell transplantation in leukemia.

7 Jan 2021

Potential role of chitinase 3-like-1 in severity of COVID-19

Now, an intriguing preprint research paper on the bioRxiv server reports the identification of an enzyme called chitinase 3-like-1 (CHI3L1) that mediates this age-dependent impact of the virus and could serve as a powerful therapeutic approach in mitigating the severity of COVID-19 in this high-risk group.

7 Jan 2021

Antibodies and inflammatory markers are pervasive in colostrum of SARS-CoV-2 infected women

A recent study, currently available on the medRxiv* preprint server, is among the first to reveal the presence of antibodies against the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in colostrum and to demonstrate elevated cytokine levels in colostrum from women exposed to the virus.

7 Jan 2021

Potential treatment approach to new COVID-19 variant

Researchers in the United States have demonstrated a potential new approach to treating infection with the new variant of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) – the agent that causes coronavirus disease 2019 (COVID-19).

7 Jan 2021

Facemasks significantly reduce simulated SARS-CoV-2 transmission in classroom setting

Researchers at the University of Wisconsin-Madison have conducted a study showing that wearing facemasks in the classroom setting can be highly effective at reducing the aerosol transmission of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) – the agent that causes coronavirus disease 2019 (COVID-19).

7 Jan 2021

Study reveals a brain mechanism underlying visual hallucinations in the blind

Some people have lost their eyesight, but they continue to "see." This phenomenon, a kind of vivid visual hallucination, is named after the Swiss doctor, Charles Bonnet, who described in 1769 how his completely blind grandfather experienced vivid, detailed visions of people, animals and objects.

7 Jan 2021

How has the COVID-19 pandemic affected the mental health of older adults? A UK case study

A team of researchers at University College London, UK, recently explored how the COVID-19 pandemic has affected the mental health of older adults across Britain.

7 Jan 2021

SARS-CoV-2 viral load in saliva may be linked to COVID-19 disease severity

Researchers at Yale University School of Medicine found that SARS-CoV-2 viral loads in saliva are higher for patients with associated risk factors and underlying conditions that lead to severe COVID-19 and death. Thus, saliva viral loads could be used to predict disease severity.

7 Jan 2021

Males at higher risk of severe COVID-19 and mortality in Indian case study

A new US-based study by researchers at Dartmouth College, the Development Data Lab, IDFC Institute, Johns Hopkins University, and the University of Chicago shows that the infection fatality rate (IFR) could be twice as high for men compared to women and increases much less at older ages compared to high-income countries.

7 Jan 2021

Which strain should SARS-CoV-2 vaccine candidates target?

A researcher at Clemson University, USA, has recently explored how governments might effectively combat the pandemic through strategic vaccination as new variants and strains of the virus emerge. The study suggests that vaccine candidates should target the fast-spreading variant, even when the initial prevalence is much lower.

7 Jan 2021

Severe COVID-19 recovered patients do not display long-lasting adaptive immune responses, finds study

A team of scientists from the University of Valencia and INCLIVA Health Research Institute, Spain, has recently investigated the durability of immune responses specifically developed against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the causative pathogen of coronavirus disease 2019 (COVID-19).

7 Jan 2021

Despite reopening of schools, serious COVID-19 is rare among children

Sweden was one of only a few countries that kept preschools, primary and lower secondary schools open during the spring of the pandemic year of 2020.

7 Jan 2021

Syndrome News and Research

Multiple withdrawal symptoms experienced by people using medical marijuana for chronic pain

Vanderbilt researcher proposes an explanatory paradigm for the cause of autism

How do SARS-CoV-2 antibodies change over time in recovered patients?

Airborne transmission of SARS-CoV-2 is possible in enclosed environments, a study finds

Researchers develop a low-cost, saliva-optimized RT-LAMP assay for faster detection of SARS-CoV-2

C-Path PRO Consortium measure now included in FDA-approved label claim

Link between fever, diarrhea, severe COVID-19, and persistent anti-SARS-CoV-2 antibodies

High-affinity SARS-CoV-2 RBD drives mutation spread, forms basis of new COVID-19 inhibitor

IU research findings could prevent common complication of blood stem cell transplantation in leukemia

Potential role of chitinase 3-like-1 in severity of COVID-19

Antibodies and inflammatory markers are pervasive in colostrum of SARS-CoV-2 infected women

Potential treatment approach to new COVID-19 variant

Facemasks significantly reduce simulated SARS-CoV-2 transmission in classroom setting

Study reveals a brain mechanism underlying visual hallucinations in the blind

How has the COVID-19 pandemic affected the mental health of older adults? A UK case study

SARS-CoV-2 viral load in saliva may be linked to COVID-19 disease severity

Males at higher risk of severe COVID-19 and mortality in Indian case study

Which strain should SARS-CoV-2 vaccine candidates target?

Severe COVID-19 recovered patients do not display long-lasting adaptive immune responses, finds study

Despite reopening of schools, serious COVID-19 is rare among children

Discover how SciY empowers scientists

Why use light scattering to analyze proteins and viral vectors?

Changing the landscape of R&D to build clinical success from the ground up

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