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FDA approves first adjuvant treatment for patients with non-small cell lung cancer

Today, the U.S. Food and Drug Administration approved Tagrisso (osimertinib) as the first adjuvant treatment for patients with non-small cell lung cancer whose tumors have a specific type of genetic mutation.

18 Dec 2020

Research at Advanced Photon Source laid the groundwork for effective COVID-19 vaccines

There is light at the end of the COVID-19 pandemic tunnel. Several vaccines against the SARS-CoV-2 virus that causes COVID-19 are now in clinical trials, with one -- developed by Pfizer/BioNTech -- already having been approved for emergency use in the United States.

18 Dec 2020

Quantifying SARS-CoV-2 transmission in large urban areas

A team of international researchers used mobility information and socio-demographic data to build a model of SARS-CoV-2 transmission to understand where, when, and how many transmission events occurred in the first wave of the pandemic in the United States.

18 Dec 2020

Higher COVID-19 mortality among certain groups in Colombia linked to structural inequalities

Researchers at the Ministry of Health and Social Protection in Bogotá, Colombia, provided evidence of socioeconomic inequalities in COVID-19 deaths in terms of age, sex, ethnicity, type of health insurance regime, and socioeconomic status.

18 Dec 2020

Study paves the way to a potential new treatment for rare terminal childhood illness

Scientists at the University of Exeter have identified a way to "rescue" cells that have genetically mutated, paving the way to a possible new treatment for rare terminal childhood illness such as mitochondrial disease.

18 Dec 2020

Very few COVID-19-positive children require hospitalization, finds case study

A team of researchers at the Divisions of Infectious Diseases, UPMC Children’s Hospital of Pittsburgh and the University of Pittsburgh, USA, sought to characterize the clinical presentation of children with COVID-19 in Western Pennsylvania.

18 Dec 2020

Remdesivir inhibits SARS-CoV-2 replication by preventing RdRp-mediated RNA translocation

A new study describes the in vitro mechanism by which remdesivir kinetically inhibits the replication of the virus that causes COVID-19, SARS-CoV-2.

18 Dec 2020

Can online health forums track the effect of COVID-19 on mental health?

A team of researchers at King's College London, UK, and other institutions used publicly accessible sources of real-world data, such as online health forums. They found that authors of COVID-19 related posts most frequently mentioned mental health symptom keywords during the first wave, followed by physical symptoms and intensive care keywords.

18 Dec 2020

Rapid no-frills detection of SARS-CoV-2 in saliva with LAMP-Cas13

A new paper that appeared as a preprint on the medRxiv* server in December 2020 describes a nucleic acid test validated on saliva samples.

18 Dec 2020

Rapid point-of-care lateral flow assay to assess the neutralizing activity of plasma against SARS-CoV-2

A new paper describes the development and validation of a rapid test to measure the neutralizing activity of serum against COVID-19 using a drop of blood.

18 Dec 2020

Study recommends blinded crossover and continued follow-ups to evaluate SARS-CoV-2 vaccine durability

A new multicenter study has shown that blinded crossover and continued follow-up of trial participants can help assess vaccine durability and potential delayed enhancement of disease.

18 Dec 2020

Could neurological complications be common even in mild COVID-19?

News-Medical talks to Dr. Pria Anand about her research into COVID-19 that suggests neurologic complications are common even in mild infections.

18 Dec 2020

Targeted Therapies Alliance provides new information, resources about the rheumatoid arthritis journey

Taking the first step and getting medical help for joint pain can be hard, but for autoimmune conditions like rheumatoid arthritis, delaying treatment can lead to increased permanent joint damage and disability.

18 Dec 2020

Experts to share the lessons learnt from COVID-19 first wave

The Physiological Society and the Intensive Care Society have come together to host an exciting three-day virtual conference this week, which will review the challenges of understanding the pathophysiological changes occurring throughout the body following COVID-19 infection.

18 Dec 2020

COVID-19 pandemic highlights the risk of using systemic corticosteroids

Healthcare workers in tropical and sub-tropical settings where strongyloidiasis is prevalent or caring for patients who have travelled to such areas, need to maintain a high level of awareness about the use of corticosteroids, including when this class of anti-inflammatories is given to patients suspected of infection with SARS-CoV-2.

17 Dec 2020

Research examines processes of lung scarring and chronic rejection of organ after transplantation

Two new papers examine the processes of lung scarring and chronic rejection of the organ after transplantation, and potential therapies to stop the graft, or transplanted organ and its tissue, from failing.

17 Dec 2020

Researchers are developing new criteria for clinical research of antiphospholipid syndrome

An international team of more than 80 collaborators led by Hospital for Special Surgery (HSS) investigators is developing new classification criteria for clinical research of antiphospholipid syndrome (APS), a life-threatening autoimmune clotting disorder.

17 Dec 2020

Continued vigilance is required in England following exit from second lockdown

Researchers in the UK have presented data from the latest in a series of community surveys assessing the prevalence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in England.

17 Dec 2020

New prognostic tool predicts the need for ICU among COVID-19 patients

Researchers in the UK have developed a prognostic tool that accurately predicts whether patients with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) – the agent causes coronavirus disease 2019 (COVID-19) – will require admission to the intensive care unit (ICU), die, or survive without escalation to ICU.

17 Dec 2020

How does the UK’s COVID-19 response compare to others in Europe?

Researchers modeled the health benefits and economic loss caused by coronavirus disease 2019 (COVID-19) in the UK and compared them to four other western European countries. Their results suggest the British Government’s response may outweigh the economic loss incurred.

17 Dec 2020

Syndrome News and Research

FDA approves first adjuvant treatment for patients with non-small cell lung cancer

Research at Advanced Photon Source laid the groundwork for effective COVID-19 vaccines

Quantifying SARS-CoV-2 transmission in large urban areas

Higher COVID-19 mortality among certain groups in Colombia linked to structural inequalities

Study paves the way to a potential new treatment for rare terminal childhood illness

Very few COVID-19-positive children require hospitalization, finds case study

Remdesivir inhibits SARS-CoV-2 replication by preventing RdRp-mediated RNA translocation

Can online health forums track the effect of COVID-19 on mental health?

Rapid no-frills detection of SARS-CoV-2 in saliva with LAMP-Cas13

Rapid point-of-care lateral flow assay to assess the neutralizing activity of plasma against SARS-CoV-2

Study recommends blinded crossover and continued follow-ups to evaluate SARS-CoV-2 vaccine durability

Could neurological complications be common even in mild COVID-19?

Targeted Therapies Alliance provides new information, resources about the rheumatoid arthritis journey

Experts to share the lessons learnt from COVID-19 first wave

COVID-19 pandemic highlights the risk of using systemic corticosteroids

Research examines processes of lung scarring and chronic rejection of organ after transplantation

Researchers are developing new criteria for clinical research of antiphospholipid syndrome

Continued vigilance is required in England following exit from second lockdown

New prognostic tool predicts the need for ICU among COVID-19 patients

How does the UK’s COVID-19 response compare to others in Europe?

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