CLARITY News and Research

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The lipid-exchanged, anatomically rigid, imaging/immunostaining compatible, tissue hydrogel (CLARITY) method was initially designed in 2013 by Chung and Deisseroth at the Stanford University School of Medicine. Using this process, post-mortem organs can be labeled for proteins and nucleic acids, enabling analysis of intact samples to create detailed 3D images.

A quantitative study of brain activity using light sheet microscopy

LaVison BioTec, developers of advanced microscopy solutions for the life sciences, report on the latest work of Li Ye, a Post-Doc Research Associate in the Deisseroth Laboratory at Stanford University he applies light sheet microscopy in a program to quantitatively study brain activity in order to better understand the processing of information.

5 Oct 2016

Study finds incomplete and ambiguous POLST forms in emergency care for elderly patients

In recent years, Physicians' Orders for Life Sustaining Treatments (POLST) forms have been seen as an important way to honor the end-of-life wishes of frail elderly or terminally ill patients who cannot speak for themselves.

30 Sep 2016

New e-rostering solution aimed at creating efficient health workforce now available

Skills for Health launches its new e-rostering solution today (28.09.16) that has the ability to transform the way the NHS utilises its entire workforce with simplicity and accuracy.

30 Sep 2016

Researchers uncover key factor for promoting wound healing after corneal injuries

In cases of severe ocular trauma involving the cornea, wound healing occurs following intervention, but at the cost of opaque scar tissue formation and damaged vision. Recent research has shown that mesenchymal stem cells (MSCs) — which can differentiate into a variety of cells, including bone, cartilage, muscle and fat cells — are capable of returning clarity to scarred corneas; however, the mechanisms by which this happens remained a mystery — until now.

29 Sep 2016

Trifocal lenses: the best chance of true spectacle independence?

Trifocal intraocular lenses (IOLs) represent the latest in premium lens technology. They are tiny, artificial lenses that are implanted into the eye during a cataract or lens replacement procedure.

28 Sep 2016

ECTRIMS, EAN collaborate to develop new therapeutic guidelines for MS

The 32nd Congress of the European Committee for Treatment and Research in Multiple Sclerosis (MS) concluded today in London (September 14-17) and one of the late breaking sessions presented the Clinical Guideline on the pharmacological management of people with Multiple Sclerosis developed jointly by ECTRIMS and European Academy of Neurology (EAN).

21 Sep 2016

Gender matching key for corneal transplants? An interview with Professor Kaye

The cornea is a transparent tissue lining the front of the eye, that is invisible tissue to the naked eye. It is a delicate tissue and disease or injury may lead to a loss of transparency or a change in the shape of the cornea, resulting in severe visual impairment.

19 Sep 2016

Research offers new insights into underlying mechanisms of deadly cystic fibrosis

A minor hiccup in the sequence of a human gene can have devastating impacts on health. Such flaws cause cystic fibrosis (CF), a disease affecting the lungs and other vital organs, often leading to death by the age of 30.

9 Sep 2016

Limited use of video games may provide benefits to children

A new study indicates that playing video games for a limited amount of time each week may provide benefits to children, but too much can be detrimental. The findings are published in the Annals of Neurology.

9 Sep 2016

Groundbreaking research unravels structure of infectious prions that cause mad cow disease

Groundbreaking research from the University of Alberta has identified the structure of the infectious prion protein, the cause of "mad cow disease" or BSE, chronic wasting disease in deer and elk and Creutzfeldt-Jakob disease in humans, which has long remained a mystery.

8 Sep 2016

Patients with noninfectious uveitis can get effective treatment from corticosteroid alternative

Patients suffering from noninfectious uveitis, a group of diseases that causes eye inflammation, can get effective treatment from a corticosteroid alternative that has previously been approved for treatment of arthritis and Crohn's disease, according to a study led by a Duke Health researcher.

8 Sep 2016

New mice study identifies trick to enhance memories

Imagine if playing a new video game or riding a rollercoaster could help you prepare for an exam or remember other critical information.

7 Sep 2016

Lens doesn't compensate for astigmatic defocus of the eye, study reveals

For people with nearsightedness (myopia), the lens doesn't compensate for growth or other changes in the structure of the eye, according to a long-term follow-up study in the September issue of Optometry and Vision Science, official journal of the American Academy of Optometry. The journal is published by Wolters Kluwer.

29 Aug 2016

ISCT announces reasons for opposing current version of REGROW Act on cell therapies

The International Society for Cellular Therapy, the global society of clinicians, researchers, regulatory specialists, technologists, and industry partners dedicated to the translation of cellular therapy into safe and effective therapies to improve patients’ lives, today announces its reasons for opposition to the current version of the REGROW Act - the US government’s legislative efforts to promote faster patient access to effective new cellular therapies.

24 Aug 2016

New research reveals crucial information about how the cornea responds to damage

Researchers at Sydney’s Centenary Institute have discovered new information about the cornea which could lead to vital new treatments aimed at repairing vision impairment and blindness.

17 Aug 2016

Dexcom launches new cloud-based solution for secure sharing of CGM data between physicians and patients

Dexcom, Inc., a leader in continuous glucose monitoring (CGM) for patients with diabetes, today announced the availability of enhanced data sharing features for physician and patient users of the Dexcom CLARITY diabetes management solution.

10 Aug 2016

FDA issues updated draft recommendations on submitting new 510(k) for modified devices

The U.S. Food and Drug Administration today issued draft updated recommendations to help manufacturers determine when they are required to notify the FDA about modifications made to certain medical devices already on the market, including a separate guidance applicable to software devices.

8 Aug 2016

Research findings may have implications for ALS and other neurological disorders

Amyotrophic lateral sclerosis (ALS, or Lou Gehrig's disease) is a progressive disorder that devastates motor nerve cells. People diagnosed with ALS slowly lose the ability to control muscle movement, and are ultimately unable to speak, eat, move, or breathe.

4 Aug 2016

New ACMG guidelines recommend NIPT as optimal initial screening test for all pregnant women

Natera, Inc., a leader in non-invasive genetic testing and the analysis of circulating cell-free DNA, applauds the new guidelines just released by the American College of Medical Genetics and Genomics, supporting the use of non-invasive prenatal tests (NIPT/NIPS) as an optimal, initial option to screen for specific genetic conditions, such as Trisomy 21 (Down syndrome) during pregnancy.

From Natera 30 Jul 2016

GSK, VentureWise partner to deliver independent educational program on COPD to GPs

A new agreement between GlaxoSmithKline and VentureWise—part of the MedicineWise Group—will see an independent educational program delivered to GPs on the topic of chronic obstructive pulmonary disease.

29 Jul 2016

CLARITY News and Research

Further Reading

A quantitative study of brain activity using light sheet microscopy

Study finds incomplete and ambiguous POLST forms in emergency care for elderly patients

New e-rostering solution aimed at creating efficient health workforce now available

Researchers uncover key factor for promoting wound healing after corneal injuries

Trifocal lenses: the best chance of true spectacle independence?

ECTRIMS, EAN collaborate to develop new therapeutic guidelines for MS

Gender matching key for corneal transplants? An interview with Professor Kaye

Research offers new insights into underlying mechanisms of deadly cystic fibrosis

Limited use of video games may provide benefits to children

Groundbreaking research unravels structure of infectious prions that cause mad cow disease

Patients with noninfectious uveitis can get effective treatment from corticosteroid alternative

New mice study identifies trick to enhance memories

Lens doesn't compensate for astigmatic defocus of the eye, study reveals

ISCT announces reasons for opposing current version of REGROW Act on cell therapies

New research reveals crucial information about how the cornea responds to damage

Dexcom launches new cloud-based solution for secure sharing of CGM data between physicians and patients

FDA issues updated draft recommendations on submitting new 510(k) for modified devices

Research findings may have implications for ALS and other neurological disorders

New ACMG guidelines recommend NIPT as optimal initial screening test for all pregnant women

GSK, VentureWise partner to deliver independent educational program on COPD to GPs

New Approach Methodologies, the 3Rs and Multimodal Imaging in Preclinical Research - eBook eBook

Latest eBooks

New horizons in drug discovery: High-throughput & target-to-therapy advances

A practical guide to lipid nanoparticle formulation and resizing

Editorial Focus eBook - Spatial and single-cell omics (1st edition)

Industry Focus eBook - Analytical Chemistry (3rd edition)

How Omics Technologies Are Transforming Biological Research and Drug Discovery

How microplastics and bacteria interact to drive antibiotic resistance

Single-cell proteomics: Revealing proteome diversity from cellular heterogeneity to non-canonical biology