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Oral hygiene and severity of COVID-19 – the connection

Their study titled, “Could there be a link between oral hygiene and the severity of SARS-CoV-2 infections?” was published in the latest issue of the journal British Dental Journal.

30 Jun 2020

Research team profiles the body's immune response to COVID-19

A team from Lawson Health Research Institute and Western University are the first in the world to profile the body's immune response to COVID-19.

25 Jun 2020

Anti-TNF drug preserves beta-cell function in newly diagnosed pediatric patients with Type 1 diabetes

In research led by a University at Buffalo pediatric endocrinologist, a drug called golimumab showed that it preserved beta-cell function in children and young adults with newly diagnosed Type 1 diabetes, according to findings from a Phase 2 study.

16 Jun 2020

Progression and severity of COVID-19 highly dependant on cytokine changes

A new review paper by the researchers from Spain, published in the journal Cytokine & Growth Factor Reviews, demonstrates how changes in the levels of cytokines and other biomolecules are associated with the presence and more serious prognosis of coronavirus disease (COVID-19).

11 Jun 2020

Turning autoimmunity drugs into anti-cancer treatments

Professor Mark Cragg speaks to News-Medical about his research which involves turning autoimmunity drugs into anti-cancer treatments.

11 Jun 2020

Indirect viral infection of the kidneys by SARS-CoV-2-induced inflammatory reaction

SARS-CoV-2-associated acute kidney injury is not uncommon. Many hospitalized COVID-19 patients - as many as 80% of critically ill COVID-19 patients, according to a current study - develop acute kidney injury, but without requiring dialysis in most cases. Proteinuria and hematuria are present in about half the cases.

8 Jun 2020

Photodynamic therapy can be used in many types and localizations of tumors

As co-author, Research Associate Ayrat Bilyalov explains, the work on photodynamic therapy has been ongoing for 5 years. The group comprises medical professionals from Kazan Federal University and Medical Center of the Presidential Administration of Kazakhstan.

8 Jun 2020

Kidney enzyme renalase a potential therapy for severe COVID-19

Researchers from Yale School of Medicine have discovered that a low blood level of an enzyme called renalase is associated with severe coronavirus disease 2019 (COVID-19).

7 Jun 2020

People suffering from rheumatoid arthritis with increased disease activity have high thrombosis risk

People suffering from rheumatoid arthritis with increased disease activity are more often affected by thrombosis.

5 Jun 2020

Blood clotting disorders may explain some of the worst symptoms of COVID-19

The hypothesis that blood clotting disorders may explain some of the worst symptoms of COVID-19, including respiratory failure and pulmonary fibrosis, was suggested in mid-April by researchers in Brazil affiliated with the University of São Paulo's Medical School (FM-USP) via an article accepted for publication by the Journal of Thrombosis.

27 May 2020

Children with COVID-19 presenting with sudden severe lung disease

Even as the COVID-19 pandemic continues to seek out new victims, puzzling new presentations are further confusing the situation. A new study published online in The Lancet Rheumatology in May 2020 reports a case of severe COVID-19 in a child who rapidly developed acute respiratory distress symptoms without prior respiratory symptoms. This case should alert clinicians to consider this diagnosis in children as well.

24 May 2020

Potential new treatment approach to fatal COVID-19

Researchers from the University of Colorado Anschutz Medical Campus and Pathways Bioscience in the United States have found that activating a transcription factor involved in oxidative stress regulation, antiviral activity, and inflammation may serve as a new treatment approach to coronavirus disease 2019 (COVID-19).

18 May 2020

Study finds bowel abnormalities in patients with COVID-19

Patients with COVID-19 can have bowel abnormalities, including ischemia, according to a new study published today in the journal Radiology.

11 May 2020

HMGB1 protein may play a key role in pulmonary inflammation, tissue damage in severe COVID-19 cases

In severe cases of COVID-19, a massive release of the endogenous protein HMGB1 in the lungs may contribute to pulmonary inflammation and tissue damage, according to a review article published today in the scientific journal Molecular Medicine.

8 May 2020

Nanostimulators can amp up stem cells' regenerative powers for muscle repair

In regenerative medicine, an ideal treatment for patients whose muscles are damaged from lack of oxygen would be to invigorate them with an injection of their own stem cells.

3 May 2020

Mapping complex peripheral immune response to severe COVID-19

In a recent article publicly available at medRxiv, researchers from Stanford have presented a single-cell atlas of the peripheral immune response to coronavirus disease (COVID-19), highlighting pertinent immunological features associated with the severe forms of the disease.

26 Apr 2020

Research characterizes iPS87 cell line as cancer-inducing, stem cell-like cell line

Oncotarget Volume 11, Issue 12 reported outside its natural niche, the cultured prostate cancer stem cells lost their tumor-inducing capability and stem cell marker expression after approximately 8 transfers at a 1:3 split ratio.

27 Mar 2020

Damaging the tumor blood vessels could be new strategy to treat oral cancer

Researchers at Okayama University have recently published a study in Cells in which they reduced the size of oral cancer tumors by damaging the blood vessels surrounding the tumor cells.

17 Mar 2020

Antioxidant treatment in acute ischemic stroke could delay onset of clinically overt dementia

Currently we are facing a dementia epidemic, with estimations showing that by 2050 approximately 131 million people will be affected.

17 Mar 2020

NTHU research team develops new treatment for cancer

A research team led by Dr. Yunching Chen and Tsai-Te Lu of National Tsing Hua University have recently developed a new treatment for cancer, in which blood vessels within malignant tumors are normalized by injecting a specially developed nanodelivery system for nitric oxide (NanoNO), which also facilitates the delivery of cancer drugs and immunocytes into the tumor.

27 Feb 2020