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NIH launches Phase 1 trial of new investigational universal influenza vaccine

Enrollment in a Phase 1 trial of a new investigational universal influenza vaccine candidate has begun at the National Institutes of Health's Clinical Center in Bethesda, Maryland.

15 Sep 2023

BU researchers receive NIH grant to identify genetic factors for Alzheimer's disease

The National Institutes of Health/National Institute on Aging recently awarded a $13.7 million grant to a project led by Boston University Chobanian & Avedisian School of Medicine principal investigators Lindsay Farrer, PhD, chief of biomedical genetics and distinguished professor of genetics, and Richard Sherva, PhD, assistant professor of medicine in biomedical genetics, for research using whole genome sequencing and other approaches to identify genetic factors for Alzheimer disease (AD) in Jews currently living in Israel who trace their ancestors to southern Spain and locations in the Middle East and North Africa (MENA) and Arab citizens of Israel.

15 Sep 2023

Purdue researcher receives $1.38 million to fight against drug-resistant malaria in developing countries

A Purdue researcher is taking a giant leap forward in the fight against drug-resistant strains of malaria in developing countries.

15 Sep 2023

Moderna’s adapted COVID-19 vaccine that targets Omicron XBB.1.5 approved by MHRA

An adapted COVID-19 vaccine from Moderna (Spikevax) that targets the Omicron XBB 1.5 subvariant, has today been authorized by the Medicines and Healthcare products Regulatory Agency (MHRA) after it was found to meet the UK regulator's standards of safety, quality and effectiveness.

15 Sep 2023

Chemotherapy drug could be repurposed to treat fatal heart failure, computer model suggests

A chemotherapy drug used to fight bone-marrow cancer also has the potential to treat and prevent potentially deadly heart failure, a powerful new drug-screening tool developed at UVA Health suggests.

15 Sep 2023

Comparative genomic analysis between systemic juvenile rheumatoid arthritis and type 1 diabetes

Shared genetic markers and immune system involvement in sJRA and T1D.

15 Sep 2023

Phase 3 study: The efficacy of monovalent SARS-CoV-2 vaccine with AS03 adjuvant in adults

The effectiveness of a novel monovalent recombinant protein vaccine against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

15 Sep 2023

Is maple syrup the ultimate natural sweetener? Researchers say it's more than just tasty!

Scientists explore the myriad benefits of maple syrup, revealing its nutritional, pharmacological, and sensory advantages over traditional sweeteners. From antioxidant and anti-inflammatory properties to controlling blood sugar and even potential anticancer effects, maple syrup is more than just a tasty topping.

14 Sep 2023

Past infections may shape your COVID booster's punch against Omicron

This in-depth study examines how previous immunity impacts the effectiveness of COVID-19 booster vaccinations and susceptibility to Omicron breakthrough infections. The research highlights the significant role of individual immune histories in shaping both humoral and cellular responses to SARS-CoV-2, urging for more tailored vaccine strategies.

14 Sep 2023

New intrauterine device is highly effective in managing postpartum bleeding

A study led by Columbia obstetricians has shown that a new intrauterine device can rapidly control postpartum hemorrhage, a major cause of severe maternal morbidity and death, in real-world situations.

14 Sep 2023

JAX offers a fully validated, clinical whole genome sequencing test

Until quite recently, it was extremely difficult to detect the variants underlying many genetic disorders. In the absence of a defined cause, clinicians have little to guide treatment for those left without a genetic diagnosis, forcing patients and families to embark on a diagnostic odyssey with no guarantee of finding answers.

14 Sep 2023

Combination immunotherapy outperforms durvalumab monotherapy in neoadjuvant NSCLC

Combination immunotherapy with the anti-PD-L1 monoclonal antibody durvalumab and other novel agents outperforms durvalumab alone in the neoadjuvant (pre-surgical) setting for early-stage non-small-cell lung cancer (NSCLC), according to researchers at The University of Texas MD Anderson Cancer Center.

14 Sep 2023

Research provides key insights into the molecular underpinnings of acute liver injury

In a study published in the journal of Genes & Diseases, a team of researchers from Chonnam National University and the Korea Research Institute of Bioscience and Biotechnology unveiled important insights into liver injury and its underlying molecular mechanisms.

14 Sep 2023

NO-ferroheme behaves as a signaling entity in the vasculature

Although a simple molecule, nitric oxide is an important signal substance that helps to reduce blood pressure by relaxing the blood vessels.

14 Sep 2023

Henry Ford Health performs first K-Clip procedure in the U.S. to treat severe tricuspid regurgitation

A team of interventional cardiologists from Henry Ford Health's Center for Structural Heart Disease recently became the first in the United States and the Western Hemisphere to repair a heart valve with severe tricuspid regurgitation in a patient using the investigational K-Clip™ Transvascular Tricuspid Repair System.

14 Sep 2023

UKHSA's flagship SIREN study enters new phase to continue surveillance of respiratory pathogens

The next phase of the study will be known as SIREN 2.0 and began in September 2023.

14 Sep 2023

Eris sublineage EG.5.1 can escape neutralizing antibodies better than other SARS-CoV-2 lineages

As a result of vaccination or infection, our immune system produces antibodies that attach to the spike protein of SARS-CoV-2, preventing the virus from entering and replicating within cells.

14 Sep 2023

Study suggests link between blood transfusions and brain hemorrhages, but further research needed

Researchers investigated whether spontaneous intracerebral hemorrhages among blood donors after blood donation were linked to the development of spontaneous ICH among transfusion recipients.

14 Sep 2023

Utilizing deep learning to enhance the accuracy of mortality forecasts in emergency rooms

Researchers enhanced the accuracy of mortality predictions in emergency departments by employing advanced data-synthesis techniques and machine-learning models.

14 Sep 2023

Oral SARS-CoV-2 vaccine shows promise in monkeys

A new paper in Biology Methods and Protocols, published by Oxford University Press, indicates that researchers studying SARS-CoV-2 may have developed new methods to administer vaccines orally, which would be both easier to administer and more effective at combatting illnesses.

13 Sep 2023

Blood News and Research

NIH launches Phase 1 trial of new investigational universal influenza vaccine

BU researchers receive NIH grant to identify genetic factors for Alzheimer's disease

Purdue researcher receives $1.38 million to fight against drug-resistant malaria in developing countries

Moderna’s adapted COVID-19 vaccine that targets Omicron XBB.1.5 approved by MHRA

Chemotherapy drug could be repurposed to treat fatal heart failure, computer model suggests

Comparative genomic analysis between systemic juvenile rheumatoid arthritis and type 1 diabetes

Phase 3 study: The efficacy of monovalent SARS-CoV-2 vaccine with AS03 adjuvant in adults

Is maple syrup the ultimate natural sweetener? Researchers say it's more than just tasty!

Past infections may shape your COVID booster's punch against Omicron

New intrauterine device is highly effective in managing postpartum bleeding

JAX offers a fully validated, clinical whole genome sequencing test

Combination immunotherapy outperforms durvalumab monotherapy in neoadjuvant NSCLC

Research provides key insights into the molecular underpinnings of acute liver injury

NO-ferroheme behaves as a signaling entity in the vasculature

Henry Ford Health performs first K-Clip procedure in the U.S. to treat severe tricuspid regurgitation

UKHSA's flagship SIREN study enters new phase to continue surveillance of respiratory pathogens

Eris sublineage EG.5.1 can escape neutralizing antibodies better than other SARS-CoV-2 lineages

Study suggests link between blood transfusions and brain hemorrhages, but further research needed

Utilizing deep learning to enhance the accuracy of mortality forecasts in emergency rooms

Oral SARS-CoV-2 vaccine shows promise in monkeys

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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