SARS CoV 2 News and Research

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A different strategy for wastewater detection of SARS-CoV-2

Researchers tested a variety of RNA concentration and extraction methods and assays to develop a protocol for testing SARS-CoV-2 in wastewater, which may help improve COVID-19 surveillance.

21 Feb 2021

Cissampelos pareira L. extracts demonstrate anti-SARS-CoV-2 activity in vitro

A team of scientists from India has recently investigated the antiviral potency of a traditional medicinal plant Cissampelos pareira L. in preventing severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. The findings reveal that both whole-plant extracts and bioactive compounds can inhibit SARS-CoV-2 replication by modulating estrogen receptor 1 (ESR1) activity.

21 Feb 2021

Evolution of the spike gene of SARS-CoV-2 for human adaptation

Researchers have found a 96% similarity in nucleotide sequence between bat coronavirus (RaTG13), isolated from Rhinolophus affinis bats in China in 2013, and SARS-CoV-2 and ~97% amino acid similarity with the Spike (S) protein. This S protein performs two essential roles, i.e., mediates receptor-binding and membrane fusion. Hence, spike protein is regarded as a key coronavirus determinant of host tropism.

21 Feb 2021

Study maps SARS-CoV-2 infected brains

Researchers in the United States and Canada have mapped the presence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in the brains of people who died from coronavirus disease 2019 (COVID-19).

21 Feb 2021

Study shows real-world effectiveness of Moderna and Pfizer/BioNtech vaccines

Researchers in the United States have conducted a study demonstrating the real-world effectiveness of the recently approved Moderna and Pfizer/BioNtech vaccines at protecting against infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) – the agent that causes coronavirus disease 2019 (COVID-19).

21 Feb 2021

Vaccination programs combined with physical distancing could contain COVID-19 resurgence

A combination of robust vaccination programs and strict physical distancing rules could avoid recurring peaks of COVID-19 without the need to rely on stay-at-home restrictions, according to a new study by epidemiologists and demographers from WorldPop at the University of Southampton, in collaboration with The Chinese University of Hong Kong.

20 Feb 2021

Researchers test the therapeutic efficacy of potential COVID-19 interventions in mouse models

Aarthi Narayanan, Associate Professor, and Lance Liotta, Co-Director, Center for Applied Proteomics and Molecular Medicine, are conducting three studies to assess the therapeutic efficacy of candidate interventions for COVID-19 in mouse models.

20 Feb 2021

Research shows impact of seasonal temperature changes on SARS-CoV-2 transmission

The SARS-CoV-2 pandemic has caused tremendous upheaval, leading to more than 2.3 million deaths worldwide and 465,000 in the United States.

20 Feb 2021

Interval between doses of Oxford COVID-19 vaccine can be safely extended to 3 months, suggests study

A 3-month interval between doses of the Oxford COVID-19 vaccine results in higher vaccine efficacy than a 6-week interval, with the first dose offering 76% protection in the 3 months between doses.

20 Feb 2021

Review provides an overview of immunogenicity profiles of leading SARS-CoV-2 vaccine candidates

In a new Review, P.J. Klasse and colleagues present an extensive overview of the immunogenicity profiles of several leading SARS-CoV-2 vaccine candidates, including several developed under the auspices of the U.S. Government's "Operation Warp Speed" program, as well as leading candidates from China and Russia.

20 Feb 2021

Intranasal COVID-19 vaccine candidate preclinically tested at UAB expected to start clinical trial

The Altimmune Inc. vaccine candidate that was tested preclinically at the University of Alabama at Birmingham last year is expected to start patient enrollment for its Phase 1 clinical trial next week.

20 Feb 2021

Live attenuated SARS-CoV-2 vaccine candidate shows protective efficacy in vivo

A new preprint on the bioRxiv* server describes the development of a live attenuated vaccine candidate to counter the growing threat of the COVID-19 pandemic.

19 Feb 2021

Llama-derived nanobodies show neutralizing activity against SARS-CoV-2 variants of concern in vitro

A new study reports the development of nanoantibodies (nAbs) – also called or nanobodiesTM or single-domain antibodies – that effectively bind the SARS-CoV-2 spike protein from the ancestral Wuhan variant as well as the recently detected UK and South African variants.

19 Feb 2021

SARS CoV 2 News and Research

A different strategy for wastewater detection of SARS-CoV-2

Cissampelos pareira L. extracts demonstrate anti-SARS-CoV-2 activity in vitro

Evolution of the spike gene of SARS-CoV-2 for human adaptation

Study maps SARS-CoV-2 infected brains

Study shows real-world effectiveness of Moderna and Pfizer/BioNtech vaccines

Vaccination programs combined with physical distancing could contain COVID-19 resurgence

Researchers test the therapeutic efficacy of potential COVID-19 interventions in mouse models

Research shows impact of seasonal temperature changes on SARS-CoV-2 transmission

Interval between doses of Oxford COVID-19 vaccine can be safely extended to 3 months, suggests study

Review provides an overview of immunogenicity profiles of leading SARS-CoV-2 vaccine candidates

Intranasal COVID-19 vaccine candidate preclinically tested at UAB expected to start clinical trial

Live attenuated SARS-CoV-2 vaccine candidate shows protective efficacy in vivo

Llama-derived nanobodies show neutralizing activity against SARS-CoV-2 variants of concern in vitro

Chicken-derived antibody shows potent neutralizing capacity against SARS-CoV-2 in vitro

COVID-19 and lung cancer have a common pathway, say researchers

Juvenile inflammatory rheumatic disease associated with higher antibody responses to seasonal coronaviruses

Scientists use computer simulations to identify future targets for treatment of Covid-19

Domestic dogs unlikely to transmit SARS-CoV-2, say researchers

Researchers find CXCR6 gene plays a role in COVID-19 severity

Does climate play a large role in SARS-CoV-2 transmission?

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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