SARS CoV 2 News and Research

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Kruppel-like factor 2 may be a major determinant of acute respiratory distress syndrome in COVID-19 patients

A study conducted at the University of Chicago, USA, has recently revealed that downregulation of an endothelial transcription factor, Kruppel-like factor 2, by SARS-CoV-2 is responsible for ARDS frequently observed in critically ill COVID-19 patients.

19 Jan 2021

Lower CD4 T cell reactivity to seasonal coronaviruses found in healthcare workers with COVID-19

A new study by US-based researchers describes the results of a study on the immune response among healthcare workers, in particular, their T cell responses predating the pandemic.

19 Jan 2021

Large study finds SARS-CoV-2 viral load is lowest in children

A new study by researchers in the Netherlands confirms the hypothesis that for SARS-CoV-2 infection, higher age is associated with increased viral loads.

19 Jan 2021

Are antibiotic regimens for critical COVID-19 patients with bacterial superinfection unnecessarily high?

A new study by researchers at Northwestern University Feinberg School of Medicine, USA, shows that antibiotic regimens for critically ill COVID-19 patients with bacterial superinfections may be promoting an unnecessarily high.

19 Jan 2021

Viral genome sequencing of wastewater can be useful for tracking new SARS-CoV-2 variants

Viral genome sequencing of wastewater can detect new SARS-CoV-2 variants before they are detected by local clinical sequencing, according to a new study reported in mBio, an open-access journal of the American Society for Microbiology.

19 Jan 2021

Early administration of ivermectin could help reduce viral transmission in COVID-19 patients

A small pilot study suggests that early administration of ivermectin can reduce viral loads and symptom duration in patients with mild COVID-19, which in turn could help reduce viral transmission.

19 Jan 2021

N501Y mutation may be associated with higher viral load, says preliminary study

A new preprint research paper posted to the medRxiv server deals with the preliminary results of a study on the so-called British variant, UI-202012/01, also known as lineage B.1.1.7 or 20B/501Y.V1.

19 Jan 2021

Prolonged shedding and multiple mutations 154 days after initial SARS-CoV-2 diagnosis reported

An interesting new preprint published on the medRxiv server describes an immunosuppressed patient with coronavirus disease 2019 (COVID-19) who continued to shed the virus for an astounding 154 days. During this period, the virus underwent numerous mutations.

19 Jan 2021

Scientists set research priorities for COVID-19 vaccines

More than 2,800 scientists from 130 countries gathered on Friday (January 15) in a virtual forum hosted by the World Health Organization (WHO) to identify knowledge gaps and set research priorities for vaccines against SARS-CoV-2, the virus that causes COVID-19.

19 Jan 2021

WHO Emergency Committee to review emerging SARS-CoV-2 variants

The COVID-19 pandemic continues to constitute a Public Health Emergency of International Concern (PHEIC), according to the WHO Emergency Committee (EC) on COVID-19.

19 Jan 2021

Global scientists are intensifying research on COVID-19

Global scientists are intensifying research into COVID-19, as the World Health Organization (WHO) moves to expand its scientific collaboration and monitoring of emerging variants of SARS-CoV-2, the virus that causes COVID-19.

18 Jan 2021

Genomics reveals distinct patterns of emergence of SARS‐CoV‐2 spike variants in Columbus, Ohio

Recently researchers from the United States reported the results of a SARS‐CoV‐2 genomic surveillance conducted between April 2020 and January 2021 in Columbus, Ohio. Their work is released as a preprint on the bioRxiv server.

18 Jan 2021

Understanding the Philippines' relative success with COVID-19

Many high-income countries have reported rising numbers of cases, while a few low-income countries such as the Philippines report a less severe COVID-19 outbreak. To date, the archipelagic country in Southeast Asia has reported 502,000 cases and 9,900 deaths among its population of around 108 million.

18 Jan 2021

About 60 percent of SARS-CoV-2 cases in England tied to new variant by the end of December

One new SARS-CoV-2 variant of concern, called 202012/01, started to spread in England in late October. A new study published on the pre-print server medRxiv found that 60 percent of daily COVID-19 cases screened by the Alderley Park Lighthouse Labs were tied to 202012/01, also known as lineage B.1.1.7 or 20B/501Y.V1. This suggests a rapid spread of the new variant across the country.

18 Jan 2021

Closed SARS-CoV-2 spikes could be a valuable component of future vaccines

Now, researchers at the Medical Research Council Laboratory of Molecular Biology, Cambridge, United Kingdom, reveal that engineered closed S constructs may be valuable immunogens that can induce neutralizing antibodies against a different pattern of epitopes. This allows for the flexibility of vaccines at both the individual and population levels.

18 Jan 2021

Essential oils from Greek herbs may protect against COVID-19

Researchers in Greece have demonstrated the antiviral effects of Cretan aromatic plant oils on severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) – the agent responsible for coronavirus disease 2019 (COVID-19).

18 Jan 2021

Research suggests seaweed used in traditional Chinese medicine could protect against COVID-19

Researchers in China have conducted a study showing that a carbohydrate found in the seaweed Ecklonia kurome blocks the activity of an enzyme that is essential for the replication of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) – the agent that causes coronavirus disease 2019 (COVID-19).

18 Jan 2021

SARS CoV 2 News and Research

Kruppel-like factor 2 may be a major determinant of acute respiratory distress syndrome in COVID-19 patients

Lower CD4 T cell reactivity to seasonal coronaviruses found in healthcare workers with COVID-19

Large study finds SARS-CoV-2 viral load is lowest in children

Are antibiotic regimens for critical COVID-19 patients with bacterial superinfection unnecessarily high?

Viral genome sequencing of wastewater can be useful for tracking new SARS-CoV-2 variants

Early administration of ivermectin could help reduce viral transmission in COVID-19 patients

N501Y mutation may be associated with higher viral load, says preliminary study

Prolonged shedding and multiple mutations 154 days after initial SARS-CoV-2 diagnosis reported

Scientists set research priorities for COVID-19 vaccines

WHO Emergency Committee to review emerging SARS-CoV-2 variants

Global scientists are intensifying research on COVID-19

Genomics reveals distinct patterns of emergence of SARS‐CoV‐2 spike variants in Columbus, Ohio

Understanding the Philippines' relative success with COVID-19

About 60 percent of SARS-CoV-2 cases in England tied to new variant by the end of December

Closed SARS-CoV-2 spikes could be a valuable component of future vaccines

Essential oils from Greek herbs may protect against COVID-19

Research suggests seaweed used in traditional Chinese medicine could protect against COVID-19

Australian scientists develop a new method for rapid synthesis of safe vaccines

SARS-CoV-2 RNA in blood serum could predict COVID-19 mortality

Modified natural killer cells show neutralizing and multivalent potential against SARS-CoV-2 in vitro

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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