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Antidepressants provide no important benefits for managing low back pain

A new systematic review led by UNSW Sydney has found that treating low back pain with antidepressant medicines provides no important benefits and has the potential to cause harm.

8 Mar 2021

New mobile app can help people diagnosed with glaucoma

Researchers from City, University London, supported by Allergan Pharmaceuticals and Glaucoma UK, have today released the latest edition of an app to help people newly diagnosed with glaucoma.

8 Mar 2021

Rare Disease Day: Illumina shines a spotlight on people living with rare diseases

With a mission of empowering the rare disease community, Illumina has today partnered with medical researchers and families to highlight the importance of genomic sequencing and to shine the spotlight on the 300 million people worldwide living with a rare disease.

8 Mar 2021

Study shows macrophages cause excess scarring after surgery

The body is amazing at healing itself. However, sometimes it can overdo it. Excess scarring after abdominal and pelvic surgery within the peritoneal cavity can lead to serious complications and sometimes death.

8 Mar 2021

Survey identifies top factor for longevity in clinical research coordinator positions

Strong, collaborative relationships with principal investigators are a key factor of longevity in clinical research coordinator positions -- an essential, but increasingly transient job in executing treatment-advancing clinical trials, Vanderbilt University Medical Center researchers found.

5 Mar 2021

Eight hallmarks of environmental exposures that contribute to disease

A new review of existing evidence proposes eight hallmarks of environmental exposures that chart the biological pathways through which pollutants contribute to disease: oxidative stress and inflammation, genomic alterations and mutations, epigenetic alterations, mitochondrial dysfunction, endocrine disruption, altered intercellular communication, altered microbiome communities, and impaired nervous system function.

5 Mar 2021

Researchers discover how adhesions form in the abdomen

Adhesions are scars in the abdomen, which can occur after surgery, often have serious consequences. Now, researchers from the University of Bern and Inselspital, University Hospital Bern, in collaboration with Canadian researchers, have discovered how such adhesions form.

5 Mar 2021

New approach using virtual clinical trials could revolutionize drug development

New cutting-edge research undertaken at the University of Leicester could revolutionize the way new drugs are developed and the way patients are cared for, through a pioneering new approach using virtual clinical trials

5 Mar 2021

Researchers identify new molecular mechanisms in chronic skin inflammation

Frequently occurring chronic skin inflammation like in atopic dermatitis (AD or neurodermatitis) and psoriasis have different causes such as genetic predisposition, stress or allergens.

5 Mar 2021

Discovery offers a precise route to treat inflammation associated with neuropathic pain

One of the hallmarks of chronic pain is inflammation, and scientists at the UNC School of Medicine have discovered that anti-inflammatory cells called MRC1+ macrophages are dysfunctional in an animal model of neuropathic pain.

5 Mar 2021

Research reveals major drivers of increased nicotine and tobacco use during COVID-19 lockdown

Pandemic-related anxiety, boredom, and irregular routines were cited as major drivers of increased nicotine and tobacco use during the initial COVID-19 "lockdown," according to research just released by Columbia University's Mailman School of Public Health.

5 Mar 2021

Digital health solution helps reduce key symptoms of chronic pain

For the first time, an app has been shown to reduce key symptoms of chronic pain. A UHN-led study evaluated the impact of Manage My Pain (MMP), a digital health solution developed by ManagingLife, on patients seen at the Iroquois Falls Family Health Team, and the Toronto Western and Toronto General Hospitals.

4 Mar 2021

Study: Having children three years apart can prevent child stunting

Having children at least three years apart can help prevent stunting in children, says a study carried out in India.

4 Mar 2021

Study reveals a small molecule inhibits SARS-CoV-2 infection in cells

Researchers found a small molecule that inhibits different virus proteins and significantly reduces infection in cells. Combined with the antiviral remdesivir, its potency increases significantly, suggesting it may be a potential antiviral candidate for the treatment of COVID-19.

4 Mar 2021

Delayed detection of oral fluid anti-SARS-CoV-2 antibodies increases the time to viral clearance

A prospective observational study has revealed that the late appearance of anti-SARS-CoV-2 antibodies in oral fluid, absence of fever as an early symptom, and elevated BMI are associated with delayed clearance of viral RNA in mild to moderate COVID-19 patients.

4 Mar 2021

Study finds high rate of cardiovascular risk factors among U.S. Hispanic/Latino population

The rate of cardiovascular risk factors among Hispanic/Latino people living in the U.S. is very high, and while they are often aware of their health conditions, less than half of the Hispanic/Latino adults with history of stroke or transient ischemic attack (TIA) had healthy blood pressure and cholesterol, and about half had healthy blood sugar levels.

4 Mar 2021

Metastudy of pregnant women reveals risk factors for COVID-19

Researchers examine the influence of pregnancy on SARS-CoV-2 infection outcomes on a wide scale, potentially informing future public messaging and COVID-19 prevention strategies.

4 Mar 2021

Coronavirus deranges the immune system in complex and deadly ways

There's a reason soldiers go through basic training before heading into combat: Without careful instruction, green recruits armed with powerful weapons could be as dangerous to one another as to the enemy.

4 Mar 2021

Study examines the variability in opioid prescriptions for common orthopedic procedures

A new review article published in the March issue of the Journal of the American Academy of Orthopaedic Surgeons (JAAOS) examines the variability that exists in opioid prescribing patterns across the United States for many common orthopedic procedures.

4 Mar 2021

Improving nurse staffing in New York hospitals could reduce deaths, save money

According to a new study published in Medical Care, improving hospital nurse staffing as proposed in pending legislation in New York state would likely save lives.

3 Mar 2021