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Study may help explain how pain decreases working memory

How do the normal pains of everyday life, such as headaches and backaches, influence our ability to think? Recent studies suggest that healthy individuals in pain also show deficits in working memory or the cognitive process of holding and manipulating information over short periods of time.

4 Feb 2021

Chronic hypoxia upregulates RNA polymerase I, alters methylation on ribosomal RNAs

Hypoxia -- where a tissue is deprived of an adequate supply of oxygen -- is a feature inside solid cancer tumors that renders them highly invasive and resistant to treatment. Study of how cells adapt to this critical stressor, by altering their metabolism to survive in a low-oxygen environment, is important to better understand tumor growth and spread.

4 Feb 2021

Prevalence of underlying medical conditions related to severe COVID-19 is higher among cancer survivors

New study finds more than half (56.4%) of cancer survivors in the United States reported having additional underlying medical conditions associated with severe COVID-19 illness.

3 Feb 2021

Study examines link between health literacy and actionable memory for medication-taking

It is important for patients to understand the information they need for making health decisions, yet studies have shown that a large segment of the population lacks the health literacy to do so.

3 Feb 2021

Clinical trials of new treatments for COVID-19 often do not include vulnerable populations

Studies examining the effectiveness of treatments for COVID-19 often do not include the very populations hardest hit by the disease, according to a new review by University of Chicago Medicine researchers.

3 Feb 2021

Extreme blood sugar swings in patients with type 2 diabetes linked to high risk of heart disease

In patients with type 2 diabetes, big swings in blood sugar levels between doctors' visits are associated with an increased risk of heart disease.

3 Feb 2021

Researchers survey repurposed drugs that inhibit SARS-CoV-2 replication in vitro

A new study by researchers at the University of Manchester, UK, reports on the compounds of interest that were identified as having potential for the treatment of COVID-19, from a library of almost 2,000 compounds from the APExBIO DiscoveryProbe library.

3 Feb 2021

Long COVID-19 symptoms not associated with reduced cell-mediated immunity, finds study

A new preprint examines Long COVID-19, aiming to identify the underlying immunologic status in such patients.

3 Feb 2021

Novel findings link nutrition to experiences of post-traumatic stress disorder

A study of factors associated with Post-Traumatic Stress Disorder (PTSD) has led to a number of novel findings linking nutrition to experiences of PTSD.

3 Feb 2021

Comprehensive study on prenatal causes of kidney disease in adults

A research group from Inselspital, Universitätsspital Bern and the University of Bern has published a comprehensive study on prenatal causes of kidney disease in adults in "Nature Communications".

3 Feb 2021

Remyelinating drug shows potential to improve vision in patients with MS

A team led by a biomedical scientist at the University of California, Riverside, reports a drug -- an estrogen receptor ligand called indazole chloride (IndCl) -- has the potential to improve vision in patients with multiple sclerosis, or MS.

2 Feb 2021

Researchers find possible cause for self-destructive immune system attacks in autoimmune diseases

Autoimmune diseases, in which the body's own immune system attacks healthy tissue, can be life-threatening and can impact all organs.

2 Feb 2021

Immune dysregulation can affect the efficacy of CAR T therapy in some lymphoma patients

Chimeric antigen receptor T-cell therapy, or CAR T, has been a breakthrough in the treatment of blood cancers such as acute lymphoblastic leukemia and diffuse large B-cell lymphoma.

2 Feb 2021

Study finds increased opioid consumption two years after intensive care

Nearly 11 percent of people admitted to an intensive care unit in Sweden between 2010 and 2018 received opioid prescriptions on a regular basis for at least six months and up to two years after discharge.

2 Feb 2021

Study identifies triggers for acute decompensation of liver cirrhosis

Chronic liver disease and even cirrhosis can go unnoticed for a long time because many patients have no symptoms: the liver suffers silently.

2 Feb 2021

Study shows link between periodontitis and COVID-19 complications

COVID-19 patients are at least three times more likely to experience complications if they also have gum disease, according to research published today in the Journal of Clinical Periodontology, the official publication of the European Federation of Periodontology.

2 Feb 2021

Differences in immune response to SARS-CoV-2 determine disease severity, study finds

Researchers investigate host responses to SARS-CoV-2, respiratory syncytial virus (RSV), and influenza virus (IV) in the nasal mucosa in children and adults.

2 Feb 2021

Study may shed light on the eco-evolutionary aspects of drug-resistant bacteria

Mehmet Orman, assistant professor of chemical and biomolecular engineering at the University of Houston Cullen College of Engineering, has received a Faculty Early Career Development (CAREER) Award from the National Science Foundation.

2 Feb 2021

Intensive BP lowering reduces cardiovascular risk in patients exposed to air pollution

Evidence suggests particulate matter is the air pollutant which poses the greatest threat to global health. Studies have shown that exposure to particulate matter smaller than 2.5 microns is associated with acute and chronic elevations in blood pressure (BP) as well as hypertension.

2 Feb 2021

Research shows a promising alternative to personalized deep brain stimulation

Millions of patients suffering from neurological and mental disorders such as depression, addiction, and chronic pain are treatment-resistant. In fact, about 30% of all major depression patients do not respond at all to any medication or psychotherapy.

2 Feb 2021

Chronic News and Research

Study may help explain how pain decreases working memory

Chronic hypoxia upregulates RNA polymerase I, alters methylation on ribosomal RNAs

Prevalence of underlying medical conditions related to severe COVID-19 is higher among cancer survivors

Study examines link between health literacy and actionable memory for medication-taking

Clinical trials of new treatments for COVID-19 often do not include vulnerable populations

Extreme blood sugar swings in patients with type 2 diabetes linked to high risk of heart disease

Researchers survey repurposed drugs that inhibit SARS-CoV-2 replication in vitro

Long COVID-19 symptoms not associated with reduced cell-mediated immunity, finds study

Novel findings link nutrition to experiences of post-traumatic stress disorder

Comprehensive study on prenatal causes of kidney disease in adults

Remyelinating drug shows potential to improve vision in patients with MS

Researchers find possible cause for self-destructive immune system attacks in autoimmune diseases

Immune dysregulation can affect the efficacy of CAR T therapy in some lymphoma patients

Study finds increased opioid consumption two years after intensive care

Study identifies triggers for acute decompensation of liver cirrhosis

Study shows link between periodontitis and COVID-19 complications

Differences in immune response to SARS-CoV-2 determine disease severity, study finds

Study may shed light on the eco-evolutionary aspects of drug-resistant bacteria

Intensive BP lowering reduces cardiovascular risk in patients exposed to air pollution

Research shows a promising alternative to personalized deep brain stimulation

A New Approach to Preventing Bladder Cancer Recurrence

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

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