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New study reveals genetic drivers of inherited bone marrow failure syndrome

Inherited bone marrow failure syndrome, or IBMFS, describes a group of disorders in which inherited genetic abnormalities impair the bone marrow's ability to produce sufficient healthy blood cells.

6 Aug 2026

Study reveals treatment gaps for atypical Alzheimer's disease patients

Many people with less common forms of Alzheimer's disease may not qualify for newer anti-amyloid treatments designed to slow the disease, according to a study published August 5, 2026, in Neurology®, the medical journal of the American Academy of Neurology.

5 Aug 2026

Long-acting HIV prevention tools could help close the gap before a vaccine arrives

A review of non-vaccine HIV interventions highlights the strong preventive effects of long-acting PrEP, sustained ART, U=U, vertical transmission programs, and voluntary medical male circumcision. Gene editing and multispecific antibodies may expand future options, but safety, cost, access, adherence, and implementation barriers remain.

5 Aug 2026

New metric detects early Alzheimer’s changes in brain's white matter

Alzheimer's disease has traditionally been studied as a condition that primarily affects the brain's gray matter, where neuronal cell bodies are located and some of the disease's most characteristic lesions accumulate.

5 Aug 2026

Scientists uncover cellular mechanism behind congenital heart defects

Congenital heart disease affects approximately two in every 100 newborns globally. But why do they occur?

4 Aug 2026

Study maps how birth order tracks disease risk across 10 million siblings

Researchers analyzing claims from more than 10 million siblings linked first-born status to higher odds of several neurodevelopmental and allergic diagnoses, while second-born status tracked with substance abuse and gastrointestinal conditions. The observational study identified 150 significant birth-order associations across the phenome, but claims data and residual confounding prevent causal conclusions.

4 Aug 2026

Korean study finds no overall childhood cancer link with maternal diabetes

Researchers followed 549,851 Korean children and found no statistically significant association between maternal diabetes and overall childhood cancer. The analysis linked maternal diabetes to an 81% higher relative risk of urinary tract cancer, but the absolute difference was only 37 additional cases per 100,000 offspring.

4 Aug 2026

Genetic study explains global spread of invasive longhorned ticks

The Asian longhorned tick, Haemaphysalis longicornis, spreads serious pathogens, including severe fever with thrombocytopenia syndrome (SFTS) virus, Rickettsia, and Theileria, and its bite can cause a meat allergy in humans.

4 Aug 2026

Airplane wastewater pilot shows how airports could track pathogens across borders

Researchers showed that airplane wastewater from a shared US-UK transatlantic route could be collected and analyzed to detect respiratory and enteric pathogen genetic material. The pilot also captured SARS-CoV-2 lineage patterns, including earlier detection of XEC on UK-origin flights, while showing the need for harmonized assays and broader sampling.

4 Aug 2026

Restricting select amino acids may mimic protein restriction’s healthy aging benefits

A review finds that restricting protein, particularly methionine, isoleucine, and valine, may improve metabolism and influence key aging pathways, largely in experimental models. Short human studies suggest metabolic benefits, but effects on lifespan remain unknown and restriction may harm people with unmet or increased protein needs.

3 Aug 2026

Advances in X chromosome inactivation open therapeutic opportunities for X-linked genetic disorders

A new review explores how advances in understanding X chromosome inactivation (XCI) are creating potential therapeutic opportunities for a range of X-linked genetic disorders, including Rett syndrome, Fabry disease, Duchenne muscular dystrophy, hemophilia, and others.

3 Aug 2026

First consensus guidelines outline GLP-1 medication use during pregnancy

As the use of GLP-1 and other incretin-based medications for obesity continues to grow worldwide, researchers at Marshall University have contributed to an international effort to address one of medicine's most pressing unanswered questions: How should these medications be used by women before, during and after pregnancy?

3 Aug 2026

Digital twin of the gut-brain axis aims to advance neurostimulation therapies

The gut and brain are in constant conversation, exchanging signals that regulate hunger and digestion, as well as the body's response to stress.

3 Aug 2026

Persistent financial hardship tracks with poorer memory and processing speed by midlife

Researchers linked persistent low income and financial hardship across early and mid-adulthood to poorer processing speed and verbal memory at age 53 in a British birth cohort. Neuroimaging suggested greater vulnerability to later brain atrophy among men, people from disadvantaged childhood backgrounds, and APOE-ε4 carriers, although these subgroup findings require replication.

2 Aug 2026

Engineered extracellular vesicles counter deadly cytokine storms in mice

The COVID-19 pandemic highlighted some severe consequences of unchecked respiratory disease, including cytokine storm.

31 Jul 2026

Accumulation of somatic mutations drives vascular damage in people with progeria

Hutchinson-Gilford progeria syndrome (HGPS) is a genetic disorder that causes remarkable premature aging.

31 Jul 2026

Ten-million-person study links semaglutide to lower COVID-19 mortality

Researchers analyzing claims from more than 10.1 million commercial insurance and Medicare Advantage enrollees found that semaglutide use was associated with a 49% lower adjusted hazard of COVID-19-related death. The observational findings corroborate earlier SELECT trial results but do not establish causation, making further prospective research essential.

30 Jul 2026

Low-fat diet lowers dietary glycation compounds for years in postmenopausal women

Researchers analyzing dietary data from 40,209 postmenopausal women found that a low-fat pattern emphasizing fruits, vegetables, and grains was associated with sustained reductions in estimated dietary advanced glycation end-product intake over approximately seven years. The findings suggest broad dietary changes may lower dAGE intake without specific cooking instructions, although the study did not measure biological AGE exposure or determine whether the reductions influenced breast cancer outcomes.

29 Jul 2026

Overactive brain immune response linked to rare, severe genetic epilepsy

An overactive immune response in the brain may play a role in Dravet Syndrome, a rare and severe genetic epilepsy that typically begins in infancy, according to Weill Cornell Medicine researchers.

29 Jul 2026

Experimental therapy helps brain cells bypass genetic deletions

Scientists at the Fralin Biomedical Research Institute at VTC have discovered how an experimental therapy can help brain cells overcome the effects of a disease-causing genetic deletion.

28 Jul 2026