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Infliximab may offer new hope for people with difficult-to-treat depression

Researchers at Emory University have found that a medication that inhibits inflammation may offer new hope for people with difficult-to-treat depression. The study was published Sept. 3 in the online version of Archives of General Psychiatry.

4 Sep 2012

TNF inhibitors best cardiac option for psoriasis patients

Use of tumor necrosis factor inhibitors is associated with a significantly reduced risk for myocardial infarction in psoriasis patients compared with use of other medications, report researchers.

31 Aug 2012

Study finds decline in 30-day mortality of acute myocardial infarction with improved treatment

Improved treatment after acute myocardial infarction and less severe patient profile have reduced 30-day mortality over the past 15 years, according to research presented at ESC Congress 2012.

29 Aug 2012

International guidelines improve outcomes after dental trauma

Adhering to the current International Association of Dental Traumatology guidelines for emergency treatment and care of traumatized teeth results in significantly lower complication rates, report researchers in Clinical Oral Investigations.

21 Aug 2012

MitoTarget Project and neurodegenerative diseases: an interview with Rebecca Pruss, Ph.D., CSO of Trophos

The MitoTarget Project was a project funded by the European Commission, under their FP7 programme. It was funding for a call published in 2007.

21 Aug 2012

Study identifies mode of death of cone photoreceptor cells in animal model of RP

Research conducted at the Angiogenesis Laboratory at Massachusetts Eye and Ear Infirmary, has for the first time, identified the mode of death of cone photoreceptor cells in an animal model of retinitis pigmentosa (RP).

21 Aug 2012

Tofacitinib shows promise in active ulcerative colitis

Tofacitinib can induce a clinical response in the majority of patients with moderate to severe, active ulcerative colitis, a placebo-controlled trial has shown.

16 Aug 2012

Common antibiotics may risk liver injury in elderly

Regulatory warnings should be considered for the antibiotics moxifloxacin and levofloxacin because of a potential risk for liver injuries in the elderly, Canadian researchers suggest.

14 Aug 2012

Tofacitinib efficacy suggested for rheumatoid arthritis

The novel oral Janus kinase inhibitor tofacitinib significantly reduces signs and symptoms of rheumatoid arthritis, report two phase III trials published in TheNew England Journal of Medicine.

13 Aug 2012

Ingredient for butter flavor in microwave popcorn is a respiratory hazard

The ingredient 2,3-pentanedione (PD), used to impart the flavor and aroma of butter in microwave popcorn, is a respiratory hazard that can also alter gene expression in the brain of rats. Manufacturers started using PD when another butter flavoring, diacetyl, was found to cause bronchiolitis obliterans, a life-threatening and nonreversible lung disease in workers who inhaled the substance.

13 Aug 2012

Pathologist identifies HPV DNA fragments in post-mortem samples after Gardasil vaccination

According to Norma Erickson, President of SaneVax Inc., testimony provided for a coroner's inquest into the death of Jasmine Renata in New Zealand by Dr. Sin Hang Lee, a pathologist on the medical staff at Connecticut's Milford Hospital, revealed the discovery of HPV DNA fragments in post-mortem samples 6 months after Gardasil vaccination.

9 Aug 2012

Adalimumab effective in maintaining remission in pediatric patients with Crohn's disease

Adalimumab (an anti-tumor necrosis factor [TNF] antibody) is effective in maintaining remission in certain pediatric patients with Crohn's disease, according to a new study in Gastroenterology, the official journal of the American Gastroenterological Association.

7 Aug 2012

Possible molecular link between circadian rhythm disturbances and increased inflammatory response

Scientists have known for some time that throwing off the body's circadian rhythm can negatively affect body chemistry. In fact, workers whose sleep-wake cycles are disrupted by night shifts are more susceptible to chronic inflammatory diseases such as diabetes, obesity and cancer.

2 Aug 2012

New compound effective at blocking damage to the retina in diabetic retinopathy

Researchers at the University of Michigan Kellogg Eye Center have identified a compound that could interrupt the chain of events that cause damage to the retina in diabetic retinopathy. The finding is significant because it could lead to a novel therapy that targets two mechanisms at the root of the disease: inflammation and the weakening of the blood barrier that protects the retina.

30 Jul 2012

MRI useful for identifying bone lesions in diabetic feet

Identification of specific bone lesions in the feet of patients with diabetes can be achieved with magnetic resonance imaging, show study findings.

25 Jul 2012

Tumor necrosis factor may play a key role in how light at night leads to depression

Chronic exposure to dim light at night can lead to depressive symptoms in rodents -- but these negative effects can be reversed simply by returning to a standard light-dark cycle, a new study suggests.

24 Jul 2012

Fat grafts ‘safe’ following breast reconstruction

Autologous fat grafting following breast reconstruction does not increase the long-term risk for tumor recurrence, US research shows.

23 Jul 2012

Limewater combination therapy can reduce root canal endotoxins

Treating root canals with a combination of chlorhexidine gel and calcium hydroxide results in significant reduction of endotoxins and neutralization of cytotoxic effects compared with the gel plus polymyxin B or saline, report Brazilian researchers.

17 Jul 2012

Altered immune function in relatives of schizophrenia patients

Schizophrenia patients and their unaffected first-degree relatives exhibit immune system alterations compared with mentally healthy individuals, researchers report.

12 Jul 2012

Researchers discover unknown mechanism that promotes growth and spread of cancer

Tiny vesicles released by tumors cells are taken up by healthy immune cells, causing the immune cells to discharge chemicals that foster cancer-cell growth and spread, according to a study by researchers at The Ohio State University Comprehensive Cancer Center - Arthur G. James Cancer Hospital and Richard J. Solove Research Institute (OSUCCC - James) and at Children's Hospital in Los Angeles.

11 Jul 2012

Necrosis News and Research

Infliximab may offer new hope for people with difficult-to-treat depression

TNF inhibitors best cardiac option for psoriasis patients

Study finds decline in 30-day mortality of acute myocardial infarction with improved treatment

International guidelines improve outcomes after dental trauma

MitoTarget Project and neurodegenerative diseases: an interview with Rebecca Pruss, Ph.D., CSO of Trophos

Study identifies mode of death of cone photoreceptor cells in animal model of RP

Tofacitinib shows promise in active ulcerative colitis

Common antibiotics may risk liver injury in elderly

Tofacitinib efficacy suggested for rheumatoid arthritis

Ingredient for butter flavor in microwave popcorn is a respiratory hazard

Pathologist identifies HPV DNA fragments in post-mortem samples after Gardasil vaccination

Adalimumab effective in maintaining remission in pediatric patients with Crohn's disease

Possible molecular link between circadian rhythm disturbances and increased inflammatory response

New compound effective at blocking damage to the retina in diabetic retinopathy

MRI useful for identifying bone lesions in diabetic feet

Tumor necrosis factor may play a key role in how light at night leads to depression

Fat grafts ‘safe’ following breast reconstruction

Limewater combination therapy can reduce root canal endotoxins

Altered immune function in relatives of schizophrenia patients

Researchers discover unknown mechanism that promotes growth and spread of cancer

Sensing a Healthier Future

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

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