Neurodegeneration News and Research

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Neurodegeneration is the umbrella term for the progressive loss of structure or function of neurons, including death of neurons.

Neuroscientists discover anti-aging molecule that repairs age-related DNA damage

MIT neuroscientists have discovered that an enzyme called HDAC1 is critical for repairing age-related DNA damage to genes involved in memory and other cognitive functions.

18 May 2020

Boehringer Ingelheim partners with CDR-Life to develop antibody fragment-based therapeutics for geographic atrophy

Boehringer Ingelheim and CDR-Life today announced they have entered into a collaboration and licensing agreement to research and develop antibody fragment-based therapeutics for geographic atrophy (GA).

From Boehringer Ingelheim International GmbH 15 May 2020

Simple molecular reagents to fight against neurodegenerative disorders

Sometimes the most complex problems actually have very simple solutions. A group of South Korean researchers reported an efficient and effective redox-based strategy for incorporating multiple functions into simple molecular reagents against neurodegenerative disorders.

11 May 2020

Scientists identify unexpected player that causes vision loss in patients with AMD

Scientists have identified an unexpected player in the immune reaction gone awry that causes vision loss in patients with age-related macular degeneration (AMD), according to a new study published today in eLife.

6 May 2020

Scientists gain new insight into the pathological mechanisms behind two neurodegenerative diseases

An international team led by Emory scientists has gained insight into the pathological mechanisms behind two devastating neurodegenerative diseases.

6 May 2020

Study shows thinking and walking speed usually decline together

Do thinking and walking go hand in hand in determining the health course of senior adults? A study published by UT Health San Antonio researchers found that, indeed, the two functions often parallel each other in determining a person's health trajectory.

6 May 2020

Researchers receive ERC grant to speed up the diagnosis of autoimmune encephalitis

Autoimmune encephalitis (AE) is a disease that affects 2-3 people out of 100,000, in which our immune system attacks our own brain causing neurological and psychiatric symptoms.

28 Apr 2020

Researchers discover a new mode of protein degradation by ubiquitin-proteasome system

The proteasome is a major proteolytic machine that regulates cellular proteostasis through selective degradation of ubiquitylated proteins.

28 Apr 2020

New potential treatment candidate identified for early type 2 diabetic retinopathy

Diabetic retinopathy is one of the main vascular complications of type 2 diabetes, and the most common cause of visual deterioration in adults.

27 Apr 2020

Study: Patients’ genetically edited stem cells successfully reversed diabetes in mice

Using induced pluripotent stem cells produced from the skin of a patient with a rare, genetic form of insulin-dependent diabetes called Wolfram syndrome, researchers transformed the human stem cells into insulin-producing cells and used the gene-editing tool CRISPR-Cas9 to correct a genetic defect that had caused the syndrome.

22 Apr 2020

Age-related DNA modifications linked with susceptibility to eye disease

National Eye Institute researchers profiling epigenomic changes in light-sensing mouse photoreceptors have a clearer picture of how age-related eye diseases may be linked to age-related changes in the regulation of gene expression.

21 Apr 2020

NEI researchers link age-related DNA modifications to susceptibility to eye disease

Researchers profiling epigenomic changes in mouse photoreceptors suggest that age-related eye diseases may be linked to gene expression.

21 Apr 2020

Reprogramming skin cells into photoreceptors to restore vision in mice

Researchers have discovered a technique for directly reprogramming skin cells into light-sensing rod photoreceptors used for vision.

15 Apr 2020

Researchers restore sight in mice by turning skin cells into light-sensing eye cells

Researchers have discovered a technique for directly reprogramming skin cells into light-sensing rod photoreceptors for vision.

15 Apr 2020

Researchers find new way to identify genes implicated in Alzheimer's disease

Alzheimer's disease is known to involve interactions among many different genes, making it difficult to pinpoint the specific mechanisms. But now, researchers from Japan have found a new way to identify genes implicated in neurodegeneration in AD.

15 Apr 2020

Toxic cell atlas can guide discovery of new drugs for neurodegeneration

A common thread in many inflammatory and neurodegenerative diseases, including multiple sclerosis (MS), is damage caused by oxidative stress. Oxidative stress occurs when cells produce toxic substances known as reactive oxygen species, which are damaging nerve cells and other cells in the body.

13 Apr 2020

Inhibition of sphingolipid metabolism and neurodegenerative diseases

Disrupting production of sphingolipids in neurons improved neurodegeneration symptoms and increased survival in a mouse model.

13 Apr 2020

MBI may give important clues about early stages of dementia

In recent years, scientists have conducted more than 100 clinical trials in the hopes of finding new indicators capable of diagnosing Alzheimer's disease prior to the manifestation of clinical symptoms such as memory loss.

8 Apr 2020

New family of molecules to join altered receptors in Alzheimer's, Parkinson's and Huntington's

An article published in the Journal of Medicinal Chemistry shows a new family of molecules with high affinity to join imidazoline receptors, which are altered in the brain of those patients with neurodegenerative diseases such as Alzheimer's, Parkinson's and Huntington's.

3 Apr 2020

Therapeutic cooling could mitigate damage to concussed cells

In the future, treating a concussion could be as simple as cooling the brain.

2 Apr 2020

Neurodegeneration News and Research

Further Reading

Neuroscientists discover anti-aging molecule that repairs age-related DNA damage

Boehringer Ingelheim partners with CDR-Life to develop antibody fragment-based therapeutics for geographic atrophy

Simple molecular reagents to fight against neurodegenerative disorders

Scientists identify unexpected player that causes vision loss in patients with AMD

Scientists gain new insight into the pathological mechanisms behind two neurodegenerative diseases

Study shows thinking and walking speed usually decline together

Researchers receive ERC grant to speed up the diagnosis of autoimmune encephalitis

Researchers discover a new mode of protein degradation by ubiquitin-proteasome system

New potential treatment candidate identified for early type 2 diabetic retinopathy

Study: Patients’ genetically edited stem cells successfully reversed diabetes in mice

Age-related DNA modifications linked with susceptibility to eye disease

NEI researchers link age-related DNA modifications to susceptibility to eye disease

Reprogramming skin cells into photoreceptors to restore vision in mice

Researchers restore sight in mice by turning skin cells into light-sensing eye cells

Researchers find new way to identify genes implicated in Alzheimer's disease

Toxic cell atlas can guide discovery of new drugs for neurodegeneration

Inhibition of sphingolipid metabolism and neurodegenerative diseases

MBI may give important clues about early stages of dementia

New family of molecules to join altered receptors in Alzheimer's, Parkinson's and Huntington's

Therapeutic cooling could mitigate damage to concussed cells

Human iPSCs: A Full Guide to Advanced in Vitro Models and Applications eBook

A New Approach to Preventing Bladder Cancer Recurrence

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

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