CLARITY News and Research

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The lipid-exchanged, anatomically rigid, imaging/immunostaining compatible, tissue hydrogel (CLARITY) method was initially designed in 2013 by Chung and Deisseroth at the Stanford University School of Medicine. Using this process, post-mortem organs can be labeled for proteins and nucleic acids, enabling analysis of intact samples to create detailed 3D images.

States wrestle with decisions regarding how to move forward on exchanges

News outlets report on how various states are responding to the implementation of the health law now that President Barack Obama has been re-elected.

14 Nov 2012

New CAM2 method could improve sound perception for users of hearing aids

A new software product developed by researchers at the University of Cambridge could greatly improve sound perception for users of hearing aids.

9 Nov 2012

Scaling Up Nutrition Movement gaining momentum, but some countries still reluctant to join, IRIN reports

"Two years after the launch of a global effort to mobilize countries in the use of scientific approaches to improve nutrition, the movement seems to be gaining momentum," IRIN reports, noting, "More than 30 countries have signed up with the Scaling Up Nutrition Movement, better known by its acronym SUN."

2 Nov 2012

Proposing standards and guidelines for Rett syndrome research

There is an urgent need for new drugs to treat Rett syndrome, a rare and severe neurological disease mainly affecting girls. A bottleneck in drug development for this syndrome is a lack of clarity at the level of preclinical research. Key researchers in this field now tackle this issue, proposing standards and guidelines for Rett syndrome research, in an Open Access review article published on Oct. 31, 2012 in Disease Models & Mechanisms (DMM).

1 Nov 2012

BioLineRx intends to conduct interim analysis of BL-1020 Phase II/III trial for schizophrenia

BioLineRx, a biopharmaceutical development company, announced today that it intends to conduct an interim analysis of the Phase II/III CLARITY trial of BL-1020, a first in class, orally available, GABA-enhanced antipsychotic for the treatment of schizophrenia.

25 Oct 2012

Methylation provides clues to gastric cancer subtypes

Research published in Science Translational Medicine shows that many gastric cancers are associated with significant epigenetic alterations along the DNA triggered by methylation.

22 Oct 2012

Viewpoints: Debate provided 'meaty' political conversation; Looking for Obama's plan on Medicare

Thursday night's vice-presidential debate was one of the best and meatiest political conversations in many years, showing that real differences on public policy can be discussed with fervor, anger, laughter and real substance. In contrast to the dismal meeting last week between President Obama and Mitt Romney, this debate gave voters a chance to evaluate the positions of the two tickets, in part because Representative Paul Ryan's nonanswers were accurate reflections of his campaign.

15 Oct 2012

Bidirectional communication between breast cancer cells and nearby MSCs cause metastasis

In recent years investigators have discovered that breast tumors are influenced by more than just the cancer cells within them. A variety of noncancerous cells, which in many cases constitute the majority of the tumor mass, form what is known as the "tumor microenvironment."

12 Oct 2012

DBP ‘remains relevant’ in stroke risk assessment

A large study has shed light on the relationship of systolic and diastolic blood pressure with stroke risk as people age.

9 Oct 2012

PENTAX Medical to release new EPK-i7000 video processor and i10 series endoscopes

PENTAX Medical, a healthcare industry leader in endoscopic imaging, will release the next generation High Definition (HD+) EPK-i7000 video processor and i10 series endoscopes during the United European Gastroenterology week from October 20-24, 2012 in Amsterdam, The Netherlands.

From PENTAX Medical Company 9 Oct 2012

DBP ‘remains relevant’ in stroke risk assessment

A large study has shed light on the relationship of systolic and diastolic blood pressure with stroke risk as people age.

5 Oct 2012

Sublingual immunotherapy highly effective for chronic allergy and asthma sufferers

Could it be that those with allergic rhinitis (hay fever) and childhood nasal allergies can finally get a break from their allergies and their allergy shots? Chicago's leading allergy, asthma, and immunology expert, Dr. Brian Rotskoff, who treats a large number of Chicago pediatric allergy patients, is happy to say, "Yes!"

5 Oct 2012

Viewpoints: Romney's surprisingly strong defense of Mass. health plan; Challenger's 'pretend' proposal for the nation

The first debate between President Obama and Mitt Romney, so long anticipated, quickly sunk into an unenlightening recitation of tired talking points and mendacity. With few sparks and little clarity on the immense gulf that truly separates the two men and their policies, Wednesday's encounter provided little guidance for voters still trying to understand the choice in next month's election.

5 Oct 2012

Researchers identify genetic origins in 10% of aortic valve malformations

Researchers at the Sainte-Justine University Hospital Center and University of Montreal have identified genetic origins in 10% of an important form of congenital heart diseases by studying the genetic variability within families.

28 Sep 2012

BioLineRx’s BL-1020 safe and effective in treating schizophrenia

BioLineRx, a biopharmaceutical development company, announced today the publication of results from the Phase II EAGLE clinical trial for BL-1020, a first in class, orally available, GABA-enhanced antipsychotic for the treatment of schizophrenia, showing that BL-1020 is safe and effective in improving schizophrenia, in addition to improving cognitive impairment associated with this condition.

28 Sep 2012

The positive or negative impact of health law is in eye of beholder

Some businesses are taking advantage of the health law's requirements as states prepare to implement it.

24 Sep 2012

BioLineRx receives U.S. patent allowance for BL-1020 to treat schizophrenia

BioLineRx, a biopharmaceutical development company, announced today that a Notice of Allowance has been received from the United States Patent and Trademark Office (USPTO) claiming the crystalline form of BL-1020, a first-in-class orally available treatment for schizophrenia.

24 Sep 2012

Ethypharm, Ampio enter definitive agreement to manufacture Zertane

Ampio Pharmaceuticals, Inc. (AMPE), a clinical stage biopharmaceutical company, with repurposed drugs and new molecular entities (NMEs) that treat inflammatory diseases, including osteoarthritis, diabetic macular edema (DME) and sexual dysfunction announced today that it has entered into a definitive agreement with Ethypharm Ltd for the manufacturing of Zertane, Ampio's drug for the treatment of premature ejaculation.

12 Sep 2012

Tips for parents to recognize signs of childhood obstructive sleep apnea

With school days upon us, a good night's sleep should be on the top of each child's list of supplies. But for some children, getting the rest they need means more than an early bedtime. At Clarity Allergy Center in Chicago, allergy, asthma, and immunology expert, Dr. Brian Rotskoff, is helping parents recognize the signs of childhood obstructive sleep apnea by carefully monitoring childhood snoring and childhood nasal allergies.

31 Aug 2012

Viewpoints: Clarity needed on GOP health plan; Blaming the poor

As soon as he moves into the White House, Mitt Romney promises, he will demand that Congress repeal the health care reform law that is President Barack Obama's signature achievement. Far less clear is how Romney and Republicans in Congress would replace the Affordable Care Act. That is a critical question for Florida, which has nearly 4 million uninsured residents and has failed to develop its own solution.

30 Aug 2012

CLARITY News and Research

Further Reading

States wrestle with decisions regarding how to move forward on exchanges

New CAM2 method could improve sound perception for users of hearing aids

Scaling Up Nutrition Movement gaining momentum, but some countries still reluctant to join, IRIN reports

Proposing standards and guidelines for Rett syndrome research

BioLineRx intends to conduct interim analysis of BL-1020 Phase II/III trial for schizophrenia

Methylation provides clues to gastric cancer subtypes

Viewpoints: Debate provided 'meaty' political conversation; Looking for Obama's plan on Medicare

Bidirectional communication between breast cancer cells and nearby MSCs cause metastasis

DBP ‘remains relevant’ in stroke risk assessment

PENTAX Medical to release new EPK-i7000 video processor and i10 series endoscopes

DBP ‘remains relevant’ in stroke risk assessment

Sublingual immunotherapy highly effective for chronic allergy and asthma sufferers

Viewpoints: Romney's surprisingly strong defense of Mass. health plan; Challenger's 'pretend' proposal for the nation

Researchers identify genetic origins in 10% of aortic valve malformations

BioLineRx’s BL-1020 safe and effective in treating schizophrenia

The positive or negative impact of health law is in eye of beholder

BioLineRx receives U.S. patent allowance for BL-1020 to treat schizophrenia

Ethypharm, Ampio enter definitive agreement to manufacture Zertane

Tips for parents to recognize signs of childhood obstructive sleep apnea

Viewpoints: Clarity needed on GOP health plan; Blaming the poor

Latest eBooks

New horizons in drug discovery: High-throughput & target-to-therapy advances

A practical guide to lipid nanoparticle formulation and resizing

Editorial Focus eBook - Spatial and single-cell omics (1st edition)

Industry Focus eBook - Analytical Chemistry (3rd edition)

How Omics Technologies Are Transforming Biological Research and Drug Discovery

How microplastics and bacteria interact to drive antibiotic resistance

Single-cell proteomics: Revealing proteome diversity from cellular heterogeneity to non-canonical biology