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Antihistamines may offer hope for long COVID patients

Researchers offer hope that an inexpensive over-the-counter medication could improve long COVID symptoms for a large proportion of these patients.

14 Feb 2022

Study demonstrates associations between COVID-19 symptom presentation and antibody assay reactivity

Researchers tested convalescent sera from individuals who had recovered from SARS-CoV-2 infection to demonstrate an association between antibody response and reported COVID-19 symptoms.

14 Feb 2022

mRNA-1273 and mRNA-1273.529 Omicron-specific boosters highly effective in mouse model

In a study posted to the bioRxiv* preprint server, a team of researchers from the United States evaluated the protective effect of the preclinical version of the current Moderna Omicron-targeted mRNA-1273.529 vaccine against the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) B.1.1.529 Omicron infection in mice.

14 Feb 2022

Study examines the viral dynamics of Hong Kong's four SARS-CoV-2 waves

Researchers evaluate the efficiency of COVID-19 elimination strategies implemented in Hong Kong.

13 Feb 2022

Scientists identify multi-kinase inhibitors that can effectively block SARS-CoV-2-mediated cytokine release

Researchers investigated the efficacy of two multi-kinase inhibitors, olverembatinib and ponatinib, in inhibiting SARS-CoV-2 omicron-mediated cytokine release in human peripheral blood mononuclear cells.

10 Feb 2022

Protective efficacy of BNT162b2 and Ad26.COV2.S against SARS-CoV-2 Omicron challenge in nonhuman primates

The study highlights the significance of mix-and-match vaccine regimens to diversify the immune responses against highly mutated variants of SARS-CoV-2 such as Omicron.

10 Feb 2022

How SARS-CoV-2 infection progresses throughout the respiratory system

Researchers discuss the progression of SARS-CoV-2 infection throughout the respiratory epithelium.

9 Feb 2022

Impact of genetic changes in Omicron variant on an immunodominant T-cell epitope

Researchers describe the impact of changes in the Omicron variant on a uniquely immunodominant spike-encoded CD8+ T-cell epitope.

9 Feb 2022

Research lays the groundwork to better understand and treat Crohn's disease

A paper published this week in Immunity, a leading research journal highlighting discoveries in immunology by Cell Press, lays the groundwork to better understand and treat Crohn's disease, a type of Inflammatory Bowel Disease (IBD).

9 Feb 2022

Single-cell sequencing provides detailed insight into early SARS-CoV-2 infection in the lungs

What is going on at the single-cell level in the first days of SARS-CoV-2 infection in the lungs?

9 Feb 2022

Study explores inflammation of endothelial cells by exosomes from COVID-19 patients

In a new study, researchers revealed that the nucleotide-binding oligomerization domain-like receptors or NOD-like receptors family pyrin domain containing 3 (NLRP3) inflammasome is activated by the exosomes from plasma in COVID-19.

9 Feb 2022

Research reveals a possible strategy to prevent B-cell acute lymphoblastic leukemia

Short-term treatment with the drug ruxolitinib prevents B-cell acute lymphoblastic leukemia (B-ALL) in mice that have a genetic predisposition to the disease.

8 Feb 2022

SARS-CoV-2 cytokine storm inhibited by curcumin nanoparticles

In a recent study published in the journal ACS Applied Bio Materials, researchers demonstrated the inhibitory potential of curcumin-encapsulated polysaccharide nanoparticles (CUR−PS-NPs) against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike protein (CoV2-SP)-stimulated cytokine storm in lung and liver epithelial cells.

8 Feb 2022

Cytokine News and Research

Antihistamines may offer hope for long COVID patients

Study demonstrates associations between COVID-19 symptom presentation and antibody assay reactivity

mRNA-1273 and mRNA-1273.529 Omicron-specific boosters highly effective in mouse model

Study examines the viral dynamics of Hong Kong's four SARS-CoV-2 waves

Scientists identify multi-kinase inhibitors that can effectively block SARS-CoV-2-mediated cytokine release

Protective efficacy of BNT162b2 and Ad26.COV2.S against SARS-CoV-2 Omicron challenge in nonhuman primates

How SARS-CoV-2 infection progresses throughout the respiratory system

Impact of genetic changes in Omicron variant on an immunodominant T-cell epitope

Research lays the groundwork to better understand and treat Crohn's disease

Single-cell sequencing provides detailed insight into early SARS-CoV-2 infection in the lungs

Study explores inflammation of endothelial cells by exosomes from COVID-19 patients

Research reveals a possible strategy to prevent B-cell acute lymphoblastic leukemia

SARS-CoV-2 cytokine storm inhibited by curcumin nanoparticles

Study uncovers a series of natural products that can inhibit the main protease of SARS-CoV-2

Colchicine holds promise to reduce the risk of severe COVID-19

Investigating the immunology of COVID-19 infected children

Study links COVID-19 inflammatory manifestations in brain lysates to Alzheimer’s Disease markers

Innate immune processes involved in SARS-CoV-2 recognition and resultant inflammation

Scientists elucidate the structure of central cellular inflammatory switch

Researchers develop influenza virus-like particle-based hybrid vaccine for both influenza and SARS-CoV-2 viruses

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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