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C-Path receives FDA contract to develop clinical outcome assessments for pediatric asthma

The Critical Path Institute announced today it has been awarded a U.S. Food and Drug Administration contract in support of ongoing development of novel clinical outcome assessments for pediatric asthma.

21 Apr 2020

Study finds how metabolism regulates sleep in worms

Can staying up late make you fat? A growing body of research has suggested that poor sleep quality is linked to an increased risk of obesity by deregulating appetite, which in turn leads to more calorie consumption.

21 Apr 2020

A new, potential treatment for nonalcoholic steatohepatitis with fibrosis

In the 2020 April 21 issue of Journal of Hepatology, a research group from the Department of Hepatology in Osaka City University Graduate School of Medicine, Japan reported that a new insight into the pathophysiology of human nonalcoholic steatohepatitis (NASH) with fibrosis and suggested a possibility of the new therapy using cytoglobin (CYGB) inducer for clinical application.

21 Apr 2020

‘It hurts our soul’: Nursing home workers struggle with thankless position

In the months before county health officials ordered the evacuation of COVID-19-plagued Magnolia Rehabilitation & Nursing Center, the facility's employees complained of bounced checks.

21 Apr 2020

Study shows why MDS cells have a competitive advantage that supports disease progression

A powerful clue has emerged in a long-running mystery about how the cells of myelodysplastic syndrome (MDS) manage to outcompete normal blood cells to cause a disease state that often leads to leukemia, according to a study published online April 20, 2020, in Nature Immunology.

21 Apr 2020

COVID-19 and immunodeficiency

COVID-19 disease, caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), is a highly infectious disease. As of today, over 170,000 people worldwide have succumbed to the infection. Reports have shown that some comorbidities and illnesses raise the risk of getting infected and also influence the severity of the disease. Having a compromised immune system can also drastically raise the risk of getting COVID-19.

21 Apr 2020

Using genome-wide CRISPR technology to identify leukemia's weakness

A team of researchers at University of California San Diego School of Medicine and Moores Cancer Center used CRISPR technology to identify key regulators of aggressive chronic myeloid leukemia, a type of cancer that remains difficult to treat and is marked by frequent relapse.

20 Apr 2020

Hypertensive pregnancy disorders may lead to mental health conditions in children

Hypertensive pregnancy disorders, especially preeclampsia, a form of high blood pressure during pregnancy, may lead to adverse mental health conditions in children, according to new research published today in Hypertension, an American Heart Association journal.

20 Apr 2020

Male-female cardiac repair differences found in heart failure survival after heart attack

The short-term acute inflammatory response triggered to mend injured cardiac tissue following a heart attack can lead to weakening of the heart's pumping function if the inflammation remains active over the long-term.

20 Apr 2020

Study shows how interactions between microbiome and the immune system contribute to liver disease

A new study by researchers in the Quadram Institute has provided insights into how interactions between gut microbes and cells of the immune system contribute to cholestatic liver disease.

20 Apr 2020

FAU scientists win $1.7 million NIH grant for research on neuroinflammation

Anxiety, depression and cognitive decline are prominent psychopathologies that together affect more than 40 million people in the United States.

20 Apr 2020

Wind turbine noise has small but significant effect on dream sleep, shows study

Wind turbine noise (WTN) influences people's perception of the restorative effects of sleep, and also has a small but significant effect on dream sleep, otherwise known as REM (rapid eye movement) sleep, a study at the University of Gothenburg shows. A night of WTN resulted in delayed and shortened REM sleep.

20 Apr 2020

New tool predicts risk of admission to long-term care home and death for dementia patients

A new tool that predicts risk of death and admission to a long-term care facility for patients with dementia may help conversations between health care providers, patients and their families, according to new research in CMAJ.

20 Apr 2020

How climate change is putting doctors in the hot seat

A 4-year-old girl was rushed to the emergency room three times in one week for asthma attacks.

20 Apr 2020

Hypertensive pregnancy disorders may lead to mental health conditions in children

Hypertensive pregnancy disorders, especially preeclampsia, may lead to adverse mental health conditions in children.

20 Apr 2020

Smoking doubles risk of severe COVID-19 disease

The fatality rate among infected people increases among the elderly and those with underlying medical conditions. Now, a new study published as a pre-print on medXriv, links smoking to the progression of COVID-19 disease, suggesting that the odds of disease progression is more than double in smokers.

20 Apr 2020

Poorer regions in the Philippines have more COVID-19 cases

The coronavirus disease (COVID-19) has dramatically affected European countries and the United States, reporting the highest number of confirmed cases. In Asia, though the number of infections gradually increases, some countries have reported high death rates, including Indonesia and the Philippines.

20 Apr 2020

Scientists estimate fatality ratio across full spectrum of COVID-19 disease

A team of researchers from Imperial College London has conducted a study aimed at calculating a reasonably accurate case fatality ratio and infection fatality ratio, which is based on Chinese data as well as international reports. The research is published on the pre-print server MedRxiv.

19 Apr 2020

Hydroxychloroquine and azithromycin treatment in 80 COVID-19 patients: short-term outcomes

The COVID-19 pandemic is still spreading around the world and affecting nearly 2.4 million people, with over 164,000 dead so far. With neither vaccine nor proven therapeutic drug being available so far, the need of the hour is for effective treatment. Now, a new study reports the potential usefulness of a combination of hydroxychloroquine and azithromycin as a treatment in mild cases of COVID-19 infection and urges the need for further evaluation and widespread use if its findings are confirmed.

19 Apr 2020

Salk scientists uncover surprising role of tuft cells in pancreatitis

Persistent inflammation of the pancreas (chronic pancreatitis) is a known risk factor for developing pancreatic cancer, the third-deadliest cancer in the United States.

18 Apr 2020

Chronic News and Research

C-Path receives FDA contract to develop clinical outcome assessments for pediatric asthma

Study finds how metabolism regulates sleep in worms

A new, potential treatment for nonalcoholic steatohepatitis with fibrosis

‘It hurts our soul’: Nursing home workers struggle with thankless position

Study shows why MDS cells have a competitive advantage that supports disease progression

COVID-19 and immunodeficiency

Using genome-wide CRISPR technology to identify leukemia's weakness

Hypertensive pregnancy disorders may lead to mental health conditions in children

Male-female cardiac repair differences found in heart failure survival after heart attack

Study shows how interactions between microbiome and the immune system contribute to liver disease

FAU scientists win $1.7 million NIH grant for research on neuroinflammation

Wind turbine noise has small but significant effect on dream sleep, shows study

New tool predicts risk of admission to long-term care home and death for dementia patients

How climate change is putting doctors in the hot seat

Hypertensive pregnancy disorders may lead to mental health conditions in children

Smoking doubles risk of severe COVID-19 disease

Poorer regions in the Philippines have more COVID-19 cases

Scientists estimate fatality ratio across full spectrum of COVID-19 disease

Hydroxychloroquine and azithromycin treatment in 80 COVID-19 patients: short-term outcomes

Salk scientists uncover surprising role of tuft cells in pancreatitis

Improving healthcare sustainability through carbon data

A New Approach to Preventing Bladder Cancer Recurrence

Bringing real-time analytics to downstream bioprocess monitoring

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