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Findings may lead to potential therapeutic strategies for rare neurodevelopmental disorder

The brain undergoes dramatic change during the first years of life. Its circuits readily rewire as an infant and then child encounters new sights and sounds, taking in the world and learning to understand it.

9 Jan 2020

Researchers identify synergistic cellular pathways that considerably amplify lifespan

Scientists at the MDI Biological Laboratory, in collaboration with scientists from the Buck Institute for Research on Aging in Novato, Calif., and Nanjing University in China, have identified synergistic cellular pathways for longevity that amplify lifespan fivefold in C. elegans, a nematode worm used as a model in aging research.

9 Jan 2020

Researchers identify new mechanism associated with p53 mutation

More than half of cancer cases worldwide are associated with genetic mutations in p53, the protein responsible for protecting DNA from changes that can lead to cancer.

9 Jan 2020

Loss of stress hormone is a hallmark of pancreatitis, shows study

In work that could have clinical implications, UT Southwestern researchers find that humans and mice with pancreatitis are deficient in a stress hormone called FGF21.

9 Jan 2020

UC Riverside research team receives NIH grant to study breast cancer

A research team led by biochemists at the University of California, Riverside, has received a four-year grant from the National Institutes of Health, or NIH, to study breast cancer -- the most common cancer in women worldwide -- and the racial disparities in the treatment of the disease.

8 Jan 2020

Rapid correction of hyperkalemia reduces mortality by half

In a new study published in the American Journal of Emergency Medicine, Adam Singer, MD, et al reported that quickly correcting high potassium levels, a condition known as hyperkalemia, in emergency department patients cut mortality in that population by half.

8 Jan 2020

Post-mortem genetic testing used to find underlying cause of sudden deaths in Amish families

Researchers used post-mortem genetic testing to find the underlying cause of multiple sudden deaths in young people and sudden cardiac arrests in two large Amish families.

8 Jan 2020

Researchers study the effects of antidepressants to identify the least harmful drugs

About one in ten women in Québec will suffer from depression during pregnancy. Without treatment, the illness carries risks for both mother and child.

8 Jan 2020

Research adds definitive evidence about how the body's earliest immune cells are formed

One day the advance could lead to a patient's own skin cells being used to produce new cells for cancer immunotherapy or to test autoimmune disease interventions.

8 Jan 2020

New ACMG Points to Consider document on use of fetal exome sequencing in prenatal care

A new Points to Consider document from the ACMG aims to assist referring physicians, laboratory geneticists, genetic counselors and other medical professionals in understanding the complexity and implications of exome sequencing in prenatal care.

8 Jan 2020

Biodegradable nanoparticle can deliver 'suicide gene' to pediatric brain tumor cells in mice

Johns Hopkins researchers report that a type of biodegradable, lab-engineered nanoparticle they fashioned can successfully deliver a "suicide gene" to pediatric brain tumor cells implanted in the brains of mice.

8 Jan 2020

New nanotech technique fights advanced-stage sepsis

Scientists have found a novel approach using nanotechnology that can fight late-stage sepsis.

8 Jan 2020

New study analyzes how consumers use vapor and tobacco heating products

The way consumers use vapor and tobacco heating products can affect the levels of harmful and potentially harmful constituents they are exposed to, and a new study has analyzed how the use of these products compares with cigarette smoking.

8 Jan 2020

Bacterial exposure is a potential environmental risk factor in developing coeliac disease

Bacterial exposure has been identified as a potential environmental risk factor in developing coeliac disease, a hereditary autoimmune-like condition that affects about one in 70 Australians.

8 Jan 2020

UChicago expert sheds light on pancreatic neuroendocrine tumors

Pancreatic cancer has been in the national spotlight lately with "Jeopardy" host Alex Trebek revealing his diagnosis. For the majority of all pancreatic cancer cases, the cancer begins in the ducts of the pancreas.

7 Jan 2020

Mayo Clinic researchers seek radical new approach to treat cocaine addition

In a radical new approach to treat cocaine addition, researchers at the Mayo Clinic are seeking approval for first-in-human studies of a single-dose gene therapy.

7 Jan 2020

NYU Langone Health announces launch of a multidisciplinary Vaccine Center

Building on its illustrious landmark-achieving history in the field of immunology, NYU Langone Health announced today the launch of a Vaccine Center that combines basic research, clinical studies, and public health outreach to prevent the spread of infectious diseases and other immunological disorders.

7 Jan 2020