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Scientists explore role of IgG4 Abs in IgG4-related disease

Autoimmune diseases are a medical conundrum. In people with these conditions, the immune system of the body, the designated defense system, starts attacking the cells or organs of its own body, mistaking the self-cells for invading disease-causing cells. Often, the cause for this spontaneous dysfunction is not clear, and hence, treatment of these diseases presents a major and ongoing challenge.

18 Dec 2019

Worse long-term control of blood sugar increases risks in diabetic trauma patients

In trauma patients with diabetes, poorer long-term control of blood glucose levels is linked to a higher risk of death and trauma-related complications, reports a study in SHOCK: Injury, Inflammation, and Sepsis: Laboratory and Clinical Approaches, Official Journal of the Shock Society.

18 Dec 2019

Study provides insight into brain mechanisms underlying compulsive drinking

Compulsive drinking may be due to dysfunction in a specific brain pathway that normally helps keep drinking in check. The results are reported in the journal Biological Psychiatry.

18 Dec 2019

Scientists evaluate HIV/AIDS, diabetes and organ transplant drugs as possible therapies for Alzheimer's

More than ever before, Alzheimer's researchers understand that a variety of approaches will be needed - most likely used in combination - for effective treatment of the disease.

18 Dec 2019

High lipoprotein(A) levels in people with type 1 diabetes add to elevated risk of cardiovascular disease

High blood levels of the lipid lipoprotein(a) in people with type 1 diabetes add to the already elevated risk of developing cardiovascular disease, researchers from Karolinska Institutet in Sweden report in a paper published in the prestigious journal Diabetes Care.

18 Dec 2019

Bio-PAT cooperation network brings users together to develop bioprocess analytics

What do beer, many vaccines or treated wastewater have in common? Biotechnological processes are involved in the production of all these substances and must be monitored and controlled so that they can work optimally.

From KNAUER Wissenschaftliche Geräte GmbH 18 Dec 2019

U-M receives $20 million gift to support research and development of life-saving therapies

The University of Michigan has received a $20 million gift from the Maxine and Stuart Frankel Foundation of Bloomfield Hills, Michigan, to support the research and development of life-saving therapies at Michigan Medicine in collaboration with other institutions.

18 Dec 2019

Moffitt researchers develop efficient method for creating mouse models to study melanoma

Genetically engineered mouse models are often used by scientists to study how the addition, deletion or mutation of genes affects the development of disease and effects of drugs.

17 Dec 2019

Leukemia patients treated with common cancer drug have heightened risk of heart failure

Patients with acute lymphoblastic leukemia or acute myeloid leukemia who are treated with anthracyclines are at a heightened risk of heart failure- most often within one year of exposure to the chemotherapy treatment, according to a new study led by researchers at Penn Medicine.

17 Dec 2019

Researchers identify novel genetic signature with prognostic value for certain breast cancers

Researchers have identified a genetic signature with prognostic value for certain kinds of breast cancer. The discovery also contributes to a better understanding of the molecular mechanisms of pathological angiogenesis, the aberrant proliferation of blood vessels that occurs during cancer and other diseases.

17 Dec 2019

Brazilian researchers create hepatic organoids by 3D bioprinting

Using human blood cells, Brazilian researchers have succeeded in obtaining hepatic organoids ("mini-livers") that perform all of the liver's typical functions, such as producing vital proteins, storing vitamins, and secreting bile, among many others.

17 Dec 2019

Scientists reveal brain mechanisms and functional regions that underlie confirmation bias

An international research team comprising neuroscientists at Virginia Tech, University College London and the University of London revealed brain mechanisms and functional regions that underlie confirmation bias -- a phenomenon where people strongly favor information that reinforces their existing opinions over contradictory ones.

17 Dec 2019

Laboratory News and Research

Scientists explore role of IgG4 Abs in IgG4-related disease

Worse long-term control of blood sugar increases risks in diabetic trauma patients

Study provides insight into brain mechanisms underlying compulsive drinking

Scientists evaluate HIV/AIDS, diabetes and organ transplant drugs as possible therapies for Alzheimer's

High lipoprotein(A) levels in people with type 1 diabetes add to elevated risk of cardiovascular disease

Bio-PAT cooperation network brings users together to develop bioprocess analytics

U-M receives $20 million gift to support research and development of life-saving therapies

Moffitt researchers develop efficient method for creating mouse models to study melanoma

Leukemia patients treated with common cancer drug have heightened risk of heart failure

Researchers identify novel genetic signature with prognostic value for certain breast cancers

Brazilian researchers create hepatic organoids by 3D bioprinting

Scientists reveal brain mechanisms and functional regions that underlie confirmation bias

Study finds new drivers of destructive inflammation

Combination of two antibiotics eradicates latent tuberculosis in macaques

Study shows the effect of obesity on routine blood tests in children

Smart, nature-inspired system provides continuous information on patient’s health

Antioxidant in green tea plant could be key to fighting tuberculosis

Stroke drug improves stem cell therapy in rat spinal cord injury models

ELRIG UK and British Pharmacological Society form strategic alliance to improve education, drive drug discovery

Study shows nilotinib drug is safe and well tolerated in patients with Parkinson's disease

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