SARS News and Research

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Llama nanobodies block SARS-CoV-2 infection in vitro

Now, a team of scientists at the United Kingdom's Rosalind Franklin Institute may have a surprising solution for the coronavirus pandemic, which has killed more than 574,000 people worldwide.

14 Jul 2020

One in three young adults at a higher risk of severe COVID-19 due to smoking, vaping

Now, a new study shows that about one in three young adults may be at risk of severe COVID-19 due to smoking and vaping habits.

14 Jul 2020

Genome comparisons between SARS-CoV-2 and other betacoronaviruses yield applicable insights

Researchers from the Venezuelan Institute for Scientific Research and the Australian National University untangle the mutational and recombinational history of the SARS-2 lineage of betacoronaviruses and their metagenomes with the use of published genomic sequences. Their findings are currently available on the bioRxiv preprint server.

14 Jul 2020

Cold sensitivity of SARS-CoV-2 could impact vaccine studies

Researchers at Duke University in Durham, USA, have made an important discovery about the spike protein on severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that could have a broad impact on vaccine studies.

14 Jul 2020

Investigational antidepressant PT150 shows antiviral activity against SARS-CoV-2

In a recent bioRxiv study, an ad hoc multi-institutional research team from the US shows that a novel hormone receptor modulator PT150 has unique and possibly additive antiviral and immunomodulatory effects – highlighting its potential role in the treatment and prophylaxis of coronavirus disease (COVID-19).

14 Jul 2020

COVID-19 may have an impact on the central nervous system of patients

Depressed mood or anxiety exhibited in COVID-19 patients may possibly be a sign the virus affects the central nervous system, according to an international study led by a University of Cincinnati College of Medicine researcher.

14 Jul 2020

Tobacco smoking and vaping nicotine may exacerbate COVID-19 inflammation

Researchers in San Diego have conducted a study showing that both smoking and the use of e-cigarettes containing nicotine and flavorings may critically exacerbate inflammation in cases of coronavirus disease 2019 (COVID-19) and significantly worsen clinical outcomes.

14 Jul 2020

Keck Medicine of USC participates in clinical trial to evaluate antiviral drug as possible COVID-19 treatment

Keck Medicine of USC physicians are enrolling patients as part of an international clinical trial to evaluate the safety and efficacy of an antiviral drug, DAS181, as a possible treatment for hospitalized patients with severe COVID-19.

14 Jul 2020

Avacta and Integumen team up for detection of novel coronavirus in waste water

Avacta Group plc, the developer of Affimer® biotherapeutics and reagents, is pleased to announce that it has entered into a collaboration with Integumen plc (“Integumen”) to evaluate recently generated Affimer reagents that bind the SARS-COV-2 spike protein for the detection of the coronavirus in wastewater, to provide a real-time alert system to warn of localized COVID-19 outbreaks.

From Avacta Life Sciences Ltd. 14 Jul 2020

Absolute Antibody and University of Zurich partner to offer novel SARS-CoV-2 sybodies

Absolute Antibody Ltd., an industry-leading provider of recombinant antibody products and services, today announced a partnership with University of Zurich to offer synthetic nanobodies against the receptor binding domain (RBD) of SARS-CoV-2, the coronavirus that causes COVID-19.

From Absolute Antibody Ltd 14 Jul 2020

Saliva promising alternative to upper airway swabs for diagnosis of SARS-CoV-2

The standard diagnostic test for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection is the reverse transcriptase-polymerase chain reaction (RT-PCR) assay. Now, a new study published on the preprint server medRxiv* in July 2020 describes the use of saliva as a sample in RT-PCR for diagnosis in place of nasopharyngeal or oropharyngeal swabs.

14 Jul 2020

UTHealth physicians investigate blood pressure drug's effect on improving COVID-19 outcomes

An interventional therapy aimed at improving survival chances and reducing the need for critical care treatment due to COVID-19 is being investigated by physicians at The University of Texas Health Science Center at Houston.

14 Jul 2020

A new measles-based COVID-19 vaccine

Now, a new study by researchers from Germany's Paul Ehrlich Institute and published on the preprint server bioRxiv in July 2020 describes a potential vaccine based on the measles vaccine, which elicits both an antibody response and cellular immunity against the virus. This also protects against the measles virus. This could be a significant weapon in the fight against these two threats.

14 Jul 2020

Yoga and meditation are potential adjunctive treatments for COVID-19

The anti-inflammatory and other beneficial effects of meditation and yoga practices make them potential adjunctive treatments of COVID-19, according to the peer-reviewed journal JACM, The Journal of Alternative and Complementary Medicine.

14 Jul 2020

Researchers review scientific articles on the role of zinc in COVID-19 prevention

Researchers from Sechenov University in collaboration with colleagues from Germany, Greece and Russia reviewed scientific articles on the role of zinc in the prevention and treatment of viral infections and pneumonia, with projections on those caused by SARS-CoV-2. The results were published in the International Journal of Molecular Medicine.

14 Jul 2020

Current assays reflect non-neutralizing antibodies, finds study

Several serologic tests have been developed to help diagnose the presence of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), either currently or in the past. However, all of them are not equally effective.

14 Jul 2020

Researchers stabilize the closed SARS-CoV-2 spike trimer

Now, a new study by researchers at Janssen Vaccines & Prevention BV and Leiden University and published on the preprint server bioRxiv uses cryoEM to reveal the structure of this trimer, in order to support both vaccine development and diagnostic testing based on antibody production.

14 Jul 2020

People with accelerated biological age at increased risk of COVID-19 symptom severity and mortality

Now, a new study published on the preprint server medRxiv in July 2020 discusses the explanation in terms of the biological aging markers in patients with severe disease, rather than the chronological age.

13 Jul 2020

Coronavirus disease immunity fades within a few months, study finds

The coronavirus disease (COVID-19) has spread rapidly across the globe, with more than 13 million people infected. Of these, an estimated 7 million have recovered from the viral infection. However, it was unclear whether being exposed to the virus would provide long-lasting immunity. Now, a new study says that SARS-CoV-2 immunity may only last for months.

13 Jul 2020

New substance library established to accelerate the systematic development of drugs

In order to accelerate the systematic development of drugs, the MX team at the Helmholtz-Zentrum Berlin (HZB) and the Drug Design Group at the University of Marburg have established a new substance library.

13 Jul 2020

SARS News and Research

Llama nanobodies block SARS-CoV-2 infection in vitro

One in three young adults at a higher risk of severe COVID-19 due to smoking, vaping

Genome comparisons between SARS-CoV-2 and other betacoronaviruses yield applicable insights

Cold sensitivity of SARS-CoV-2 could impact vaccine studies

Investigational antidepressant PT150 shows antiviral activity against SARS-CoV-2

COVID-19 may have an impact on the central nervous system of patients

Tobacco smoking and vaping nicotine may exacerbate COVID-19 inflammation

Keck Medicine of USC participates in clinical trial to evaluate antiviral drug as possible COVID-19 treatment

Avacta and Integumen team up for detection of novel coronavirus in waste water

Absolute Antibody and University of Zurich partner to offer novel SARS-CoV-2 sybodies

Saliva promising alternative to upper airway swabs for diagnosis of SARS-CoV-2

UTHealth physicians investigate blood pressure drug's effect on improving COVID-19 outcomes

A new measles-based COVID-19 vaccine

Yoga and meditation are potential adjunctive treatments for COVID-19

Researchers review scientific articles on the role of zinc in COVID-19 prevention

Current assays reflect non-neutralizing antibodies, finds study

Researchers stabilize the closed SARS-CoV-2 spike trimer

People with accelerated biological age at increased risk of COVID-19 symptom severity and mortality

Coronavirus disease immunity fades within a few months, study finds

New substance library established to accelerate the systematic development of drugs

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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