Peripheral Artery Disease News and Research

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Peripheral arterial disease (PAD) occurs when leg arteries become narrowed or blocked by plaque. These blockages can result in severe pain for patients, limited physical mobility, and life-threatening non-healing leg ulcers. According to the American Heart Association, this condition affects approximately 8 to 12 million Americans. With only about 25 percent of PAD patients undergoing treatment, it is a disease that is largely under-diagnosed and under-treated. If left untreated, PAD can lead to critical leg ischemia, a condition where not enough blood is being delivered to the leg to keep the tissue alive. Total loss of circulation to the legs and feet can cause gangrene and lead to amputation.

Good hydration may slow down aging and prolong disease-free life

Adults who stay well-hydrated appear to be healthier, develop fewer chronic conditions, such as heart and lung disease, and live longer than those who may not get sufficient fluids, according to a National Institutes of Health study published in eBioMedicine.

2 Jan 2023

New scientific statement highlights the impact of telehealth in cardiovascular disease management

Telehealth is a proven and valuable option for people with cardiovascular disease, however, there are limitations to its use in rural and under-resourced communities, according to a new scientific statement from the American Heart Association, published today in the Association's flagship peer-reviewed journal Circulation.

14 Nov 2022

Restoring blood flow to the legs reduces pain, improves quality of life for people with peripheral artery disease

Restoring blood flow to the legs, whether through bypass surgery or a less invasive artery-opening procedure with a stent, reduced pain and improved quality of life for people with peripheral artery disease (PAD), according to preliminary, late-breaking research presented today at the American Heart Association's Scientific Sessions 2022.

7 Nov 2022

Bypass surgery linked to fewer amputations in people with severe peripheral artery disease

People with severe peripheral artery disease, or PAD, who received bypass surgery to improve blood flow to their legs and feet had 65 percent fewer repeat procedures and 27% fewer amputations than those who had minimally invasive procedures such as angioplasty and stenting, according to preliminary late-breaking research presented today at the American Heart Association's Scientific Sessions 2022.

7 Nov 2022

Open bypass surgery results in better outcomes for specific patients with severe form of peripheral artery disease

Performing open bypass surgery to restore circulation for people with a severe form of peripheral artery disease (PAD) – a condition that limits blood flow to the legs and feet – resulted in better outcomes for specific patients compared to a less-invasive procedure, a National Institutes of Health-supported clinical research trial has found.

7 Nov 2022

New approach provides better understanding of atherosclerosis in the leg arteries

Cardiovascular experts at UVA Health have found a new way to track peripheral artery disease (PAD), a serious medical condition involving atherosclerosis in the leg arteries that affects more than 200 million people worldwide.

26 Sep 2022

Research highlights the serious health implications of young-onset type 2 diabetes

Men and women who are diagnosed with type 2 diabetes (T2D) aged 40 or younger are far more likely to develop cardiovascular disease (CVD) and die prematurely than those under 40 in the general population, according to new research to be presented at this year's European Association for the Study of Diabetes (EASD) Annual Meeting in Stockholm, Sweden (19-23 Sept).

7 Sep 2022

What is the association between COVID-19 and thrombotic events?

In a new study, researchers assessed the association of COVID-19 and influenza with thrombotic events among patients.

18 Aug 2022

Exercise that induces leg pain seems to be beneficial for people with peripheral artery disease

Walking for exercise at a pace that induced pain or discomfort improved walking ability among people with peripheral artery disease, or PAD, according to new research published today in the Journal of the American Heart Association, an open access, peer-reviewed journal of the American Heart Association.

27 Jul 2022

Smoking increases risk of severe COVID-19 outcomes in hospitalized patients

New research assessed the association of smoking with COVID-19 complications.

20 Jul 2022

The past, present and future of aspirin in cardiovascular disease prevention

The International Aspirin Foundation A special edition issue of the Aspirin Summaries has been published '125 years of aspirin - the role of aspirin in CVD' issue 2022 .

29 Jun 2022

Study finds no difference in survival between patients treated with paclitaxel drug-coated devices and non-DCDs

New long-term data from the Safety Assessment of Femoropopliteal Endovascular Treatment With PAclitaxel-coated Devices (SAFE-PAD) study were presented today as late-breaking clinical research at the Society for Cardiovascular Angiography & Interventions (SCAI) 2022 Scientific Sessions.

20 May 2022

Insomnia common in heart disease patients and linked with subsequent cardiovascular events

Nearly half of heart disease patients have insomnia, according to research presented at ESC Preventive Cardiology 2022, a scientific congress of the European Society of Cardiology, and published in SLEEP Advances.

7 Apr 2022

Powerhouse-pruning protein may also help make energy rapidly available for growing new blood vessels

A protein that helps keep our cell powerhouses working at a premium appears to also help make energy rapidly available when it's time to make new blood vessels.

4 Apr 2022

Unusual partners are key to making more blood vessels

Insufficient oxygen to an area like the heart or legs, called hypoxia, is a cue to our bodies to make more blood vessels, and scientists have found some unusual partners are key to making that happen.

8 Mar 2022

Role of leptin in immune modulation and pathophysiology of COVID-19

A recent review paper in the journal Frontiers in Physiology discusses the role of leptins in infection with SARS-CoV-2 that triggered the ongoing COVID-19 pandemic.

13 Jan 2022

Environmental exposure to low-levels of toxic metals may increase risk of clogged arteries

Environmental exposure to low-levels of the toxic metals arsenic, cadmium and titanium appears to increase the risk of plaque buildup in arteries in the neck, heart and legs, according to new research published today in the American Heart Association's journal Arteriosclerosis, Thrombosis and Vascular Biology (ATVB).

9 Dec 2021

Hispanic adults with peripheral artery disease more likely to be admitted to the hospital through the ER

Hispanics adults hospitalized for treatment of symptoms of peripheral artery disease (PAD) were more likely to access this care by going to the emergency room (ER), and they experienced longer and more expensive hospitalizations than non-Hispanic white patients with PAD, according to preliminary research to be presented at the American Heart Association's Quality of Care and Outcomes (QCOR) Research Scientific Sessions 2021.

8 Nov 2021

Key protein in the blood could help identify patients at risk of severe peripheral artery disease

To track cardiovascular health, doctors measure blood pressure, cholesterol levels and blood sugar, among a number of other cardiovascular disease risk factors.

30 Sep 2021

BUSM assistant professor awarded $2.1 million for peripheral artery disease research

Peripheral artery disease (PAD) is a major cause of limb loss. It is estimated that PAD affects between 8.5 and 12 million Americans, with a prevalence that has increased by about 25 percent over the preceding decade.

21 Sep 2021

Peripheral Artery Disease News and Research

Good hydration may slow down aging and prolong disease-free life

New scientific statement highlights the impact of telehealth in cardiovascular disease management

Restoring blood flow to the legs reduces pain, improves quality of life for people with peripheral artery disease

Bypass surgery linked to fewer amputations in people with severe peripheral artery disease

Open bypass surgery results in better outcomes for specific patients with severe form of peripheral artery disease

New approach provides better understanding of atherosclerosis in the leg arteries

Research highlights the serious health implications of young-onset type 2 diabetes

What is the association between COVID-19 and thrombotic events?

Exercise that induces leg pain seems to be beneficial for people with peripheral artery disease

Smoking increases risk of severe COVID-19 outcomes in hospitalized patients

The past, present and future of aspirin in cardiovascular disease prevention

Study finds no difference in survival between patients treated with paclitaxel drug-coated devices and non-DCDs

Insomnia common in heart disease patients and linked with subsequent cardiovascular events

Powerhouse-pruning protein may also help make energy rapidly available for growing new blood vessels

Unusual partners are key to making more blood vessels

Role of leptin in immune modulation and pathophysiology of COVID-19

Environmental exposure to low-levels of toxic metals may increase risk of clogged arteries

Hispanic adults with peripheral artery disease more likely to be admitted to the hospital through the ER

Key protein in the blood could help identify patients at risk of severe peripheral artery disease

BUSM assistant professor awarded $2.1 million for peripheral artery disease research

Event guide: 4th Extra-Hepatic Lipid-Based Nanoparticles Delivery Summit eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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