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Study shows potential benefits of efgartigimod as a treatment for immune thrombocytopenia

Patients taking efgartigimod, a drug being studied for use to treat chronic primary immune thrombocytopenia (ITP), exhibited a significantly greater improvement in platelet counts which are essential to clotting and stopping bleeding, compared to those taking a placebo, according to results reported from the ADVANCE IV clinical trial, which was conducted globally, including at Georgetown University Medical Center.

12 Dec 2022

ASCOT trial pinpoints most efficient level of blood thinning treatment for hospitalized COVID-19 patients

The COVID-19 global pandemic remains a major public health challenge. ASCOT researchers aim to discover which treatments are most effective in patients hospitalized with COVID-19.

12 Dec 2022

Discovery of biomarkers lays the groundwork for predicting preeclampsia

A discovery by Stanford School of Medicine researchers of biomarkers in the blood and urine of women with a dangerous complication of pregnancy could lead to a low-cost test to predict the condition.

9 Dec 2022

Researchers seek to reduce Chikungunya virus-caused joint pain with new drug

Oregon Health & Science University researchers and partners are developing what could become the first-ever treatment against the debilitating joint pain that can last months or years after becoming infected with the emerging Chikungunya virus.

9 Dec 2022

An epigenetic modification improves the defense against infections, research shows

During infections, the hematopoietic system switches from normal to emergency mode. This improves the defense against the pathogens.

9 Dec 2022

Researchers discover a previously unknown mechanism that drives aging

Northwestern University researchers have discovered a previously unknown mechanism that drives aging.

9 Dec 2022

Study proposes a new concept for treating COVID-19 associated weight loss

Losing too much weight when infected with COVID-19 has been linked to worse outcomes. Now, researchers at Karolinska Institutet in Sweden have discovered that SARS-CoV-2 infection fuels blood vessel formation in fat tissues, thus revving up the body's thermogenic metabolism.

9 Dec 2022

What is the importance of vitamin B12 supplementation in plant-based diets?

Researchers emphasize the importance of vitamin B12 supplementation for individuals consuming a plant-based or vegan diet.

9 Dec 2022

UH researchers investigate how traumatic experiences affect mental and physical health of migrants

In a first of its kind study, University of Houston psychology researchers are investigating how the trauma experienced by migrants before and during the journey to the United States affects their mental and physical health.

8 Dec 2022

Complementary, alternative therapies for heart failure have some benefits and potential risks

There are some benefits and potentially serious risks when people with heart failure use complementary and alternative medicines (CAM), to manage symptoms, so involving the health care team is important for safety, according to a new American Heart Association scientific statement published today in the Association's flagship, peer-reviewed journal Circulation.

8 Dec 2022

Researchers develop a virtual molecular library of thousands of 'command sentences' for cells

Using new machine learning techniques, researchers at UC San Francisco (UCSF), in collaboration with a team at IBM Research, have developed a virtual molecular library of thousands of "command sentences" for cells, based on combinations of "words" that guided engineered immune cells to seek out and tirelessly kill cancer cells.

8 Dec 2022

Estrogen replacement therapy may be a tool to mitigate delirium

Delirium is common among women with urinary tract infections (UTIs) - especially those who have experienced menopause.

8 Dec 2022

Novel gene mutation linked to rare premature-aging syndrome

UT Southwestern researchers have discovered a new form of progeria, a rare premature-aging syndrome, in a man from Malaysia and traced its cause to a novel gene mutation.

8 Dec 2022

Antibodies against gentamicin associated with increased risk of type 1 diabetes in children

Antibodies produced against the commonly used antibiotic, gentamicin, appear to increase the risk of type 1 diabetes in children already genetically at risk, scientists say.

8 Dec 2022

Addition of yoga to regular exercise training supports cardiovascular health and wellbeing

A three-month pilot study of patients with hypertension appearing in the Canadian Journal of Cardiology, published by Elsevier, demonstrates that adding yoga to a regular exercise training regimen supports cardiovascular health and wellbeing and is more effective than stretching exercises.

8 Dec 2022

What are the associations of metabolome, microbiome, and immune perturbations with severe COVID-19?

In a new study, researchers observed that coronavirus disease 2019 (COVID-19) progression and inflammatory responses are associated with changes in the metabolome and microbiome.

8 Dec 2022

Adult females exhibit impaired muscle and pulmonary function after COVID-19 recovery

In a new study, researchers examined muscle and pulmonary dysfunction during moderate exercise in adult females who recovered from coronavirus disease 2019 (COVID-19).

8 Dec 2022

Booster COVID-19 mRNA vaccinations marginally increase the durability of neutralizing antibody responses

Researchers investigated the immunological mechanisms behind the decreasing efficacy of COVID-19 vaccines by evaluating the durability and magnitude of neutralizing antibodies and memory B and T cell responses to booster doses of mRNA COVID-19 vaccine.

8 Dec 2022

More states to consider extending postpartum Medicaid coverage beyond two months

For patients with sickle cell disease, fertility care is about reproductive justice

Teonna Woolford has always wanted six kids. Why six? "I don't know where that number came from. I just felt like four wasn't enough," said Woolford, a Baltimore resident. "Six is a good number."

8 Dec 2022

Blood News and Research

Study shows potential benefits of efgartigimod as a treatment for immune thrombocytopenia

ASCOT trial pinpoints most efficient level of blood thinning treatment for hospitalized COVID-19 patients

Discovery of biomarkers lays the groundwork for predicting preeclampsia

Researchers seek to reduce Chikungunya virus-caused joint pain with new drug

An epigenetic modification improves the defense against infections, research shows

Researchers discover a previously unknown mechanism that drives aging

Study proposes a new concept for treating COVID-19 associated weight loss

What is the importance of vitamin B12 supplementation in plant-based diets?

UH researchers investigate how traumatic experiences affect mental and physical health of migrants

Complementary, alternative therapies for heart failure have some benefits and potential risks

Researchers develop a virtual molecular library of thousands of 'command sentences' for cells

Estrogen replacement therapy may be a tool to mitigate delirium

Novel gene mutation linked to rare premature-aging syndrome

Antibodies against gentamicin associated with increased risk of type 1 diabetes in children

Addition of yoga to regular exercise training supports cardiovascular health and wellbeing

What are the associations of metabolome, microbiome, and immune perturbations with severe COVID-19?

Adult females exhibit impaired muscle and pulmonary function after COVID-19 recovery

Booster COVID-19 mRNA vaccinations marginally increase the durability of neutralizing antibody responses

More states to consider extending postpartum Medicaid coverage beyond two months

For patients with sickle cell disease, fertility care is about reproductive justice

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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