Neurodegeneration News and Research

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Neurodegeneration is the umbrella term for the progressive loss of structure or function of neurons, including death of neurons.

CZI announces over $51 million funding to fight neurodegenerative diseases

Today, the Chan Zuckerberg Initiative announced $64.25 million in funding and its selection of 17 early career investigators and nine collaborative science teams to launch the CZI Neurodegeneration Challenge Network

5 Dec 2018

Researchers uncover genes that lead to excessive tau in dementia

Researchers have identified two major groups of genes involved in the mutations that lead to excess production of tau, a protein involved in dementia.

3 Dec 2018

Study provides new insights into how prions enter the brain

The spread of prions to the brain does not occur by direct transmission across the blood-brain barrier, according to a study published November 29 in the open-access journal PLOS Pathogens by Annika Keller and Adriano Aguzzi of the University Hospital Zürich, and colleagues.

3 Dec 2018

National Institutes of Health awards grant to MSU professors for research on neurodegenerative disease

A research collaboration between three Montana State University faculty members recently received a grant to help fund their study on the connection between a rare genetic neurological disease and metabolism, the human gut microbiome and degeneration of the nervous system.

30 Nov 2018

New dye is a step towards personalized neuromedical prophylaxis of the future

Signs of neurodegenerative diseases, visible years before the emergence of clinical manifestations, can be detected during the examination of medical samples by means of fluorescence microscopy.

29 Nov 2018

Automating Data Capture and Image Analysis in Continuous Experiments

An interview with Lindy O’Clair, discussing the challenges of studying neuronal systems over time, and the development of an automated platform by Sartorius.

From Sartorius 19 Nov 2018

Inhibition of one protein clears toxic clumps seen in Parkinson's disease, study finds

A defining feature of Parkinson's disease is the clumps of alpha-synuclein protein that accumulate in the brain's motor control area, destroying dopamine-producing neurons.

14 Nov 2018

Advanced AI and big data methods to tackle dementia

Sports concussions, Parkinson's disease, and hormone therapy for cancer - all can have memory loss as symptoms. But do the biochemical processes of each type of memory loss have anything to reveal about the memory loss that is part of Alzheimer's disease?

13 Nov 2018

Salk researchers receive $19.2 million to unravel mysteries of age-related cognitive decline

A team of Salk Institute researchers led by President Rusty Gage has been awarded $19.2 million over eight years by the American Heart Association-Allen Initiative in Brain Health and Cognitive Impairment to investigate mechanisms underlying Alzheimer's disease and aging-related cognitive decline and uncover new therapies.

12 Nov 2018

Cardiovascular and Alzheimer's disease share common genetics in some individuals, study shows

Genetics may predispose some people to both Alzheimer's disease and high levels of blood lipids such as cholesterol, a common feature of cardiovascular disease, according to a new study by an international team of researchers led by scientists at UC San Francisco and Washington University School of Medicine in St. Louis.

9 Nov 2018

Interaction strength and time delays can change how synchronization appears and develops

In physical, biological and technological systems, the time that a system's components take to influence each other can affect the transition to synchronization, an important finding that improves understanding of how these systems function, according to a study led by Georgia State University.

8 Nov 2018

Scientists to discuss latest research on spatial cognition in aging and neurodegeneration

Scientists from Germany and abroad will be meeting in Magdeburg from 27 to 29 November 2018 to discuss latest research on spatial cognition in aging and neurodegeneration. The symposium is hosted by the German Center for Neurodegenerative Diseases.

7 Nov 2018

US businessman offers $5 million to UTSA College to incubate Alzheimer's challenge

To expand the understanding and explanation of Alzheimer's disease, United States businessman James Truchard has given a $5 million USD gift to The University of Texas at San Antonio College of Sciences to establish the Oskar Fischer Project.

5 Nov 2018

Genetic inhibition of SARM1 prevents axonal degeneration in nervous systems

Disarm Therapeutics, a biotechnology company creating a new class of disease-modifying therapeutics for patients with axonal degeneration, a central driver of neurological disease, today announced data demonstrating that genetic inhibition of SARM1 prevents axonal degeneration in the central, ocular and peripheral nervous systems.

5 Nov 2018

New form of therapy may stop or reverse progressive vision loss

A new form of therapy may halt or even reverse a form of progressive vision loss that, until now, has inevitably led to blindness.

1 Nov 2018

Potential new biomarkers may aid early detection of glaucoma

Researchers at Ruhr-Universität Bochum have identified new potential biomarkers that may facilitate early detection of glaucoma in patients. Moreover, they ascertained that the mutation of a certain gene in mice causes intraocular pressure elevation.

25 Oct 2018

Modeling Alzheimer’s Disease Using Microfluidics

An interview with Dr. Joseph Park, the incorporation of astrocytes into the Alzheimer’s-in-a-dish culture system and it's applications in drug development.

24 Oct 2018

Scientists develop new class of compounds for treatment of progressive neurodegenerative disorder

St. Jude Children's Research Hospital investigators have developed a new class of compounds that extended the lives and eased symptoms of mice with a progressive neurodegenerative human disorder.

23 Oct 2018

Study: Atg2 tethers pre-autophagosomal membrane to endoplasmic reticulum during autophagosome formation

Postdoctoral Researcher Tetsuya Kotani, Associate Professor Hitoshi Nakatogawa, Honorary Professor Yoshinori Ohsumi and colleagues at Tokyo Institute of Technology have analyzed the Atg protein Atg2, whose function had been completely unknown, and have discovered that Atg2 tethers the pre-autophagosomal membrane to the endoplasmic reticulum during autophagosome formation.