Laboratory News and Research

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Robust replication model of human noroviruses may pave way for effective therapeutics

Zebrafish larvae can serve as a robust replication model of human noroviruses, according to a study published September 19 in the open-access journal PLOS Pathogens by Joana Rocha-Pereira, Peter de Witte and Johan Neyts, of KU Leuven in Belgium, and colleagues.

From PLOS ONE 25 Sep 2019

Space-based investigation helps address challenges involved in learning more about the human brain

Researchers studying neurological diseases face several daunting challenges. For one thing, these conditions may take years or even decades to develop.

25 Sep 2019

TUM researchers reveal how chaperones detect immature immune signaling proteins

The cells of our immune system constantly communicate with one another by exchanging complex protein molecules.

24 Sep 2019

'Report card' on American diet: Adults consuming more low-quality carbs and fat than recommended

Despite years of steady advice and guidance on healthy eating, a 'report card' on the American diet shows adults are still consuming too many low-quality carbohydrates and more saturated fat than recommended, according to researchers at the Friedman School of Nutrition Science and Policy at Tufts University and the Harvard T.H. Chan School of Public Health.

24 Sep 2019

Wistar awarded more than $12 million to study opioid use in HIV-infected people

The Wistar Institute was awarded two major grants totaling more than $12 million from the National Institute on Drug Abuse, part of the National Institutes of Health, to fund an international multidisciplinary clinical research consortium spearheaded by Wistar's HIV Research Program.

24 Sep 2019

Ear's tiny outer hair cells regulate sound sensitivity, study shows

The ear’s tiny outer hair cells adjust the sensitivity of neighboring inner hair cells to sound levels rather than acting like an amplifier, suggests a new study published today in eLife.

24 Sep 2019

Bath researchers identify promising prostate cancer drug candidates

Cancer researchers from the University of Bath have identified some promising drug candidates by using high-throughput screening methods to test tens of thousands of molecules.

24 Sep 2019

Mice also fidget like humans while making decisions

Almost everyone fidgets, said Cold Spring Harbor Laboratory Associate Professor Anne Churchland. She referred to a collage of videos she compiled of different people rocking back and forth in their chairs, clicking a pen, shaking their legs.

24 Sep 2019

Non-viral gene delivery method more effective and safer than standard viral approaches

The non-viral, bio-inspired gene delivery method developed by researchers at RMIT University has proven effective in laboratory tests and is safer than standard viral approaches.

24 Sep 2019

$Deep brain stimulation found to be safe, effective in the treatment of refractory severe tinnitus$

Deep brain stimulation found to be safe, effective in the treatment of refractory severe tinnitus

Researchers from the University of California San Francisco and Veterans Affairs Health Care System, San Francisco investigated the safety and efficacy of deep brain stimulation in the treatment of refractory severe tinnitus in a small group of patients.

24 Sep 2019

Penn State scientists receive AHA grant, propose new way to prevent thrombosis

Two Penn State biomedical engineering faculty members have received a two-year, $200,000 grant from the American Heart Association (AHA) to explore potential solutions to thrombosis, or blood clot formation, a prevalent issue with blood-contacting medical devices such as heart valves, blood pumps and cardiac stents.

24 Sep 2019

New AGA guideline on evaluation of chronic diarrhea released

Diagnosing patients with chronic watery diarrhea can be difficult for health care providers, since several causes with specific therapies, such as inflammatory bowel disease (IBD), microscopic colitis and chronic infection, need to be ruled out.

23 Sep 2019

Ruthenium probes shed new light on cause of Alzheimer's disease

Rice University researchers have found a way to track the formation of soluble amyloid beta peptide aggregates implicated in the onset of Alzheimer's disease.

23 Sep 2019

Study sheds light on mechanisms behind correlated electrical activity in neurons

"Like a book in which the single pages are not all different but carry small portions of common text, or like a group of people who whistle a very similar tune": this is how our brain cells work, say scientists. It is the phenomenon of "co-relation", in which individual neurons do not always act as independent units in receiving and transmitting information but as a group of individuals with similar and simultaneous actions.

23 Sep 2019

Version of an antibiotic drug extends survival in mice with lethal pediatric brain tumors

Versions of an antibiotic drug called DON first isolated from soil bacteria more than 60 years ago have shown promising signs of extending survival in mice models of especially lethal pediatric brain tumors marked by the high expression of a cancer-causing gene known as the MYC oncogene, according to results of two studies from researchers at the Johns Hopkins Kimmel Cancer Center.

23 Sep 2019

U-M and Karmanos receive NCI grant to find new solutions for prostate cancer

Michigan's two elite cancer programs are joining forces to find new solutions for prostate cancer. The University of Michigan Rogel Cancer and the Barbara Ann Karmanos Cancer Institute have received a prestigious $9.2 million grant from the National Cancer Institute.

23 Sep 2019

Tanzania keeping Ebola under wraps

Ebola could be already on the prowl in Tanzania, but the government is keeping it a secret. This is the official position of the World Health Organization (WHO), who says multiple cases have been secretly reported to it.

23 Sep 2019

African bacterium resists almost all drugs

It looks like it’s time to pay the piper. The first extensively drug-resistant (XDR) strain of Salmonella typhimurium, called ST313 sublineage II.1, has cropped up in the Democratic Republic of Congo (DRC). This fails to respond to any of the antibiotics that are commonly used in the DRC, except for ciprofloxacin. And to make things worse, one sample has been isolated that shows incomplete response even to this last drug.

22 Sep 2019

Mutations in specific protein make dengue virus resistant to vaccines and therapeutics

Dengue virus infects about 400 million people annually around the world, with a high prevalence in tropical and sub-tropical regions.

20 Sep 2019

NIH awards research grants to develop learning health care system for early psychosis treatment

The National Institutes of Health awarded six research grants for studies to develop a learning health care system for the treatment of early psychosis.

20 Sep 2019

Laboratory News and Research

Robust replication model of human noroviruses may pave way for effective therapeutics

Space-based investigation helps address challenges involved in learning more about the human brain

TUM researchers reveal how chaperones detect immature immune signaling proteins

'Report card' on American diet: Adults consuming more low-quality carbs and fat than recommended

Wistar awarded more than $12 million to study opioid use in HIV-infected people

Ear's tiny outer hair cells regulate sound sensitivity, study shows

Bath researchers identify promising prostate cancer drug candidates

Mice also fidget like humans while making decisions

Non-viral gene delivery method more effective and safer than standard viral approaches

Deep brain stimulation found to be safe, effective in the treatment of refractory severe tinnitus

Penn State scientists receive AHA grant, propose new way to prevent thrombosis

New AGA guideline on evaluation of chronic diarrhea released

Ruthenium probes shed new light on cause of Alzheimer's disease

Study sheds light on mechanisms behind correlated electrical activity in neurons

Version of an antibiotic drug extends survival in mice with lethal pediatric brain tumors

U-M and Karmanos receive NCI grant to find new solutions for prostate cancer

Tanzania keeping Ebola under wraps

African bacterium resists almost all drugs

Mutations in specific protein make dengue virus resistant to vaccines and therapeutics

NIH awards research grants to develop learning health care system for early psychosis treatment

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