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Cambridge scientists use synthetic biology approach to destroy SARS-CoV-2 virus

Cambridge scientists have used synthetic biology to create artificial enzymes programmed to target the genetic code of SARS-CoV-2 and destroy the virus, an approach that could be used to develop a new generation of antiviral drugs.

16 Nov 2022

Whole-genome sequencing reveals five new subgroups of chronic lymphocytic leukemia

A collaborative study led by the University of Oxford as part of the UK's 100,000 Genomes Project, published in Nature Genetics today, has defined five new subgroups of the most common type of blood cancer, chronic lymphocytic leukemia (CLL) and associated these with clinical outcomes.

16 Nov 2022

Research findings could bolster the effectiveness of immune-checkpoint therapy

Immune checkpoint inhibitors such as Keytruda and Opdivo work by unleashing the immune system's T cells to attack tumor cells.

16 Nov 2022

Research reveals new treatment avenue for pediatric high grade gliomas harboring a genetic mutation

Researchers at the University of Michigan Rogel Cancer Center have identified a novel treatment approach to an aggressive type of pediatric brain cancer, using therapies already approved to treat cancer.

16 Nov 2022

Research in young rats shows how hormonal contraceptives may affect the brain

Reproductive health experts consider hormonal contraceptives good choices for adolescents because they're safe and highly effective at preventing pregnancy, but one aspect of their effect on the teenage body remains a mystery – whether and how they modify the developing brain.

16 Nov 2022

Researchers are developing calculator that weighs risk and benefit of taking osteoporosis drugs

Osteoporosis is a major, worsening public health problem and bisphosphonates which help restore a healthier balance of bone production and resorption, have been a relatively inexpensive, successful treatment, particularly for those at highest risk for fractures.

16 Nov 2022

COVID-19 mRNA boosters induce robust but non-durable immune response in the elderly

A study published in the journal Frontiers in Immunology describes that the third booster dose of coronavirus disease 2019 (COVID-19) effectively induces an immune response against immunologically more fit variants of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). However, the immunity induced by the booster vaccination is transient and gradually declines over time.

15 Nov 2022

Vitamin D can reduce severity and spread of COVID-19

In a recent study published in the Scientific Reports journal, researchers in the United States assessed the relationship between supplementation with vitamin D and coronavirus disease 2019 (COVID-19) and related mortality.

15 Nov 2022

Researchers make first bone marrow 'organoids' to capture key features of human bone marrow

Scientists from Oxford University and the University of Birmingham have made the first bone marrow 'organoids' that capture the key features of human bone marrow.

15 Nov 2022

Development of a potent, broadly protective vaccine against all SARS-CoV-2 variants

In a recent study published in the journal npj Vaccines, researchers in China designed, produced, and evaluated the neutralization efficacy of a recombinant coronavirus disease 2019 (COVID-19) vaccine containing four hot-spot substitution mutations based on a prefusion-stabilized severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike protein (S) trimer.

15 Nov 2022

Unique cellular signature can accurately detect obstructive sleep apnea in children

Researchers from the University of Missouri School of Medicine have discovered how obstructive sleep apnea (OSA) changes the profiles of immune cells in the blood, leading to a unique cellular signature that can accurately detect obstructive sleep apnea in children.

15 Nov 2022

Utilizing marine sources to extract DHA to treat Alzheimer’s

The anti-neurodegenerative effects of docosahexaenoic acid (DHA) and DHA-rich phospholipids (DH-PL) derived from fisheries and aquaculture byproducts.

15 Nov 2022

Study explores the links between childhood adversity and cardiovascular disease in early adulthood

Children who experience adversity, including serious family illness or death, poverty, neglect, or dysfunctional and stressful family relationships, are at increased risk of developing diseases of the heart or blood vessels in early adulthood.

15 Nov 2022

1 in 10 new moms diagnosed with high blood pressure in the year after childbirth

In an analysis of more than 2,400 women, about 1 in 10 without a history of blood pressure issues were diagnosed with high blood pressure in the year after childbirth, according to a research article published today in Hypertension, an American Heart Association journal.

15 Nov 2022

Pancreas transplant more beneficial than other treatments for people with diabetes

Results of pancreas transplantation continue to improve and up to 90% of recipients with diabetes enjoy freedom from both insulin therapy and the need for close glucose monitoring following the procedure, according to a new paper published in the Endocrine Society's Journal of Clinical Endocrinology & Metabolism.

15 Nov 2022

Polyphenols in Mediterranean diet may modulate COVID-19 inflammation

Researchers discuss the beneficial role of polyphenolic plant compounds in the Mediterranean diet in the prevention and treatment of COVID-19.

15 Nov 2022

Lipid screening and dyslipidemia intervention in adolescence may stop atherosclerosis progression

Consistently elevated lipids and dyslipidemia in early life were associated with worsening subclinical atherosclerosis, but simulated lipid treatment in late adolescence stopped atherosclerosis progression, a paper published in Atherosclerosis concludes.

15 Nov 2022

Researchers identify 35 genes that are highly expressed in patients with long-term Lyme disease

Researchers at the Icahn School of Medicine at Mount Sinai in New York have identified 35 genes that are particularly highly expressed in people with long-term Lyme disease.

15 Nov 2022

Parasites associated with leprosy may have the ability to regenerate livers

Leprosy is one of the world's oldest and most persistent diseases but the bacteria that cause it may also have the surprising ability to grow and regenerate a vital organ.

15 Nov 2022

Early mobility contributes to higher survival rates for COVID-19 patients receiving ECMO

A Texas cardiac subspecialty hospital with seven years of experience with extracorporeal membrane oxygenation (ECMO) changed its treatment paradigm during the COVID-19 pandemic, finding that progressive mobility and a more aggressive application of rehabilitation therapies contributed to significantly higher survival rates for its patients with COVID-19 receiving ECMO.

15 Nov 2022

Blood News and Research

Cambridge scientists use synthetic biology approach to destroy SARS-CoV-2 virus

Whole-genome sequencing reveals five new subgroups of chronic lymphocytic leukemia

Research findings could bolster the effectiveness of immune-checkpoint therapy

Research reveals new treatment avenue for pediatric high grade gliomas harboring a genetic mutation

Research in young rats shows how hormonal contraceptives may affect the brain

Researchers are developing calculator that weighs risk and benefit of taking osteoporosis drugs

COVID-19 mRNA boosters induce robust but non-durable immune response in the elderly

Vitamin D can reduce severity and spread of COVID-19

Researchers make first bone marrow 'organoids' to capture key features of human bone marrow

Development of a potent, broadly protective vaccine against all SARS-CoV-2 variants

Unique cellular signature can accurately detect obstructive sleep apnea in children

Utilizing marine sources to extract DHA to treat Alzheimer’s

Study explores the links between childhood adversity and cardiovascular disease in early adulthood

1 in 10 new moms diagnosed with high blood pressure in the year after childbirth

Pancreas transplant more beneficial than other treatments for people with diabetes

Polyphenols in Mediterranean diet may modulate COVID-19 inflammation

Lipid screening and dyslipidemia intervention in adolescence may stop atherosclerosis progression

Researchers identify 35 genes that are highly expressed in patients with long-term Lyme disease

Parasites associated with leprosy may have the ability to regenerate livers

Early mobility contributes to higher survival rates for COVID-19 patients receiving ECMO

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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